IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i5p2261-d505451.html
   My bibliography  Save this article

Association between Urinary Phthalate Metabolite Concentration and Atopic Dermatitis in Korean Adolescents Participating in the Third Korean National Environmental Health Survey, 2015–2017

Author

Listed:
  • Sang-Woo Kim

    (Department of Occupational and Environmental Medicine, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul 04401, Korea)

  • Jeongho Lee

    (Department of Pediatrics, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul 04401, Korea)

  • Soon-Chan Kwon

    (Department of Occupational and Environmental Medicine, Soonchunhyang University Cheonan Hospital, 31 Suncheonhyang 6-gil, Dongnam-gu, Cheonan-si 31151, Korea)

  • June-Hee Lee

    (Department of Occupational and Environmental Medicine, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul 04401, Korea)

Abstract

Previous studies have highlighted the potential health effects of phthalate exposure, such as atopic dermatitis and asthma. However, evidence supporting the association between phthalate exposure and atopic dermatitis is limited and based on data collected from Western populations. This study aimed to analyze the association between phthalate exposure and atopic dermatitis in Korean adolescents aged 12–17 years using a nationally representative dataset. We conducted a cross-sectional study using a publicly available dataset from the third Korean National Environmental Health Survey ( n = 797). We divided the study participants into four quartiles according to urinary phthalate metabolite concentrations. The odds ratio of having atopic dermatitis was calculated using the first quartile as the reference group in binary logistic regression. We found that in the logistic regression model, both the urinary Mono-(2-ethyl-5-carboxypentyl) phthalate (MECCP; OR: 1.81; CI: 1.01–3.25) and Mono-benzyl phthalate (MBzP; OR: 1.81; CI: 1.01–3.25) concentrations in the highest quartile were positively associated with atopic dermatitis. The atopic dermatitis group had a significantly higher mean urinary MECCP and MBzP concentration. In the future, longitudinal studies involving repeated measurements are warranted to analyze the long-term effects of phthalate.

Suggested Citation

  • Sang-Woo Kim & Jeongho Lee & Soon-Chan Kwon & June-Hee Lee, 2021. "Association between Urinary Phthalate Metabolite Concentration and Atopic Dermatitis in Korean Adolescents Participating in the Third Korean National Environmental Health Survey, 2015–2017," IJERPH, MDPI, vol. 18(5), pages 1-10, February.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2261-:d:505451
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/5/2261/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/5/2261/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Matthias Wormuth & Martin Scheringer & Meret Vollenweider & Konrad Hungerbühler, 2006. "What Are the Sources of Exposure to Eight Frequently Used Phthalic Acid Esters in Europeans?," Risk Analysis, John Wiley & Sons, vol. 26(3), pages 803-824, June.
    2. Jaakkola, J.J.K. & Parise, H. & Kislitsin, V. & Lebedeva, N.I. & Spengler, J.D., 2004. "Asthma, Wheezing, and Allergies in Russian Schoolchildren in Relation to New Surface Materials in the Home," American Journal of Public Health, American Public Health Association, vol. 94(4), pages 560-562.
    3. Jaakkola, J.J.K. & Øie, L. & Nafstad, P. & Botten, G. & Samuelsen, S.O. & Magnus, P., 1999. "Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway," American Journal of Public Health, American Public Health Association, vol. 89(2), pages 188-192.
    4. Jaakkola, J.J.K. & Verkasalo, P.K. & Jaakkola, N., 2000. "Plastic wall materials in the home and respiratory health in young children," American Journal of Public Health, American Public Health Association, vol. 90(5), pages 797-799.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. W. S. Kwan & D. Nikezic & Vellaisamy A. L. Roy & K. N. Yu, 2020. "Multiple Stressor Effects of Radon and Phthalates in Children: Background Information and Future Research," IJERPH, MDPI, vol. 17(8), pages 1-27, April.
    2. Hyunok Choi & Norbert Schmidbauer & John Spengler & Carl-Gustaf Bornehag, 2010. "Sources of Propylene Glycol and Glycol Ethers in Air at Home," IJERPH, MDPI, vol. 7(12), pages 1-25, December.
    3. Branislav Kolena & Ida Petrovicova & Tomas Pilka & Zuzana Pucherova & Michal Munk & Bohumil Matula & Viera Vankova & Peter Petlus & Zita Jenisova & Zdenka Rozova & Sona Wimmerova & Tomas Trnovec, 2014. "Phthalate Exposure and Health-Related Outcomes in Specific Types of Work Environment," IJERPH, MDPI, vol. 11(6), pages 1-12, May.
    4. Jing Zhao & Yukari Nagai & Wei Gao & Tao Shen & Youming Fan, 2023. "The Effects of Interior Materials on the Restorativeness of Home Environments," IJERPH, MDPI, vol. 20(14), pages 1-11, July.
    5. Samantha E. Serrano & Catherine J. Karr & Noah S. Seixas & Ruby H. N. Nguyen & Emily S. Barrett & Sarah Janssen & Bruce Redmon & Shanna H. Swan & Sheela Sathyanarayana, 2014. "Dietary Phthalate Exposure in Pregnant Women and the Impact of Consumer Practices," IJERPH, MDPI, vol. 11(6), pages 1-23, June.
    6. Mehzabeen Mannan & Sami G. Al-Ghamdi, 2021. "Indoor Air Quality in Buildings: A Comprehensive Review on the Factors Influencing Air Pollution in Residential and Commercial Structure," IJERPH, MDPI, vol. 18(6), pages 1-25, March.
    7. Barend L. van Drooge & Ioar Rivas & Xavier Querol & Jordi Sunyer & Joan O. Grimalt, 2020. "Organic Air Quality Markers of Indoor and Outdoor PM 2.5 Aerosols in Primary Schools from Barcelona," IJERPH, MDPI, vol. 17(10), pages 1-16, May.
    8. Cong Liu & Zhe Liu & John C Little & Yinping Zhang, 2013. "Convenient, Rapid and Accurate Measurement of SVOC Emission Characteristics in Experimental Chambers," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-9, August.
    9. Sibylle Hildenbrand & Thomas Gabrio & Gerhard Volland, 2019. "Inter-Day Variability of Metabolites of DEHP and DnBP in Human Urine—Comparability of the Results of Longitudinal Studies with a Cross-Sectional Study," IJERPH, MDPI, vol. 16(6), pages 1-15, March.
    10. Te Liu & Yiyang Jia & Liting Zhou & Qi Wang & Di Sun & Jin Xu & Juan Wu & Huaiji Chen & Feng Xu & Lin Ye, 2016. "Effects of Di-(2-ethylhexyl) Phthalate on the Hypothalamus–Uterus in Pubertal Female Rats," IJERPH, MDPI, vol. 13(11), pages 1-15, November.
    11. Jiahui Wang & Zefei Xu & Jingyu Yao & Maochao Hu & Yuewen Sun & Cong Dong & Zhongming Bu, 2022. "Identification of Phthalates from Artificial Products in Chinese Kindergarten Classrooms and the Implications for Preschool Children’s Exposure Assessments," IJERPH, MDPI, vol. 19(13), pages 1-12, June.
    12. A. Jarosova & J. Harazim & P. Suchy & L. Kratka & V. Stancova, 2009. "The distribution and accumulation of phthalates in the organs and tissues of chicks after the administration of feedstuffs with different phthalate concentrations," Veterinární medicína, Czech Academy of Agricultural Sciences, vol. 54(9), pages 427-434.
    13. Cécile Marie & Sophie Cabut & Françoise Vendittelli & Marie-Pierre Sauvant-Rochat, 2016. "Changes in Cosmetics Use during Pregnancy and Risk Perception by Women," IJERPH, MDPI, vol. 13(4), pages 1-16, March.
    14. Maryam Zare Jeddi & Mohamad Eshaghi Gorji & Ivonne M. C. M. Rietjens & Jochem Louisse & Yuri Bruinen de Bruin & Roman Liska, 2018. "Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents," IJERPH, MDPI, vol. 15(11), pages 1-22, October.
    15. Subin Park & Bung-Nyun Kim & Soo-Churl Cho & Yeni Kim & Jae-Won Kim & Ju-Young Lee & Soon-Beom Hong & Min-Sup Shin & Hee Jeong Yoo & Hosub Im & Jae Hoon Cheong & Doug Hyun Han, 2014. "Association between Urine Phthalate Levels and Poor Attentional Performance in Children with Attention-Deficit Hyperactivity Disorder with Evidence of Dopamine Gene-Phthalate Interaction," IJERPH, MDPI, vol. 11(7), pages 1-14, June.
    16. Rune Becher & Johan Øvrevik & Per E. Schwarze & Steinar Nilsen & Jan K. Hongslo & Jan Vilhelm Bakke, 2018. "Do Carpets Impair Indoor Air Quality and Cause Adverse Health Outcomes: A Review," IJERPH, MDPI, vol. 15(2), pages 1-14, January.
    17. Fiorella Lucarini & Marc Blanchard & Tropoja Krasniqi & Nicolas Duda & Gaëlle Bailat Rosset & Alessandro Ceschi & Nicolas Roth & Nancy B. Hopf & Marie-Christine Broillet & Davide Staedler, 2021. "Concentrations of Seven Phthalate Monoesters in Infants and Toddlers Quantified in Urine Extracted from Diapers," IJERPH, MDPI, vol. 18(13), pages 1-14, June.
    18. Maria Dickson‐Spillmann & Michael Siegrist & Carmen Keller & Matthias Wormuth, 2009. "Phthalate Exposure Through Food and Consumers’ Risk Perception of Chemicals in Food," Risk Analysis, John Wiley & Sons, vol. 29(8), pages 1170-1181, August.
    19. Constantin C. Bungau & Codruta Bendea & Tudor Bungau & Andrei-Flavius Radu & Marcela Florina Prada & Ioana Francesca Hanga-Farcas & Cosmin Mihai Vesa, 2024. "The Relationship between the Parameters That Characterize a Built Living Space and the Health Status of Its Inhabitants," Sustainability, MDPI, vol. 16(5), pages 1-35, February.
    20. Yun-Jung Yang & Taehyen Kim & Yeon-Pyo Hong, 2021. "Urinary Phthalate Levels Associated with the Risk of Nonalcoholic Fatty Liver Disease in Adults: The Korean National Environmental Health Survey (KoNEHS) 2012–2014," IJERPH, MDPI, vol. 18(11), pages 1-9, June.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2261-:d:505451. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.