IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v11y2014i6p5628-5639d36467.html
   My bibliography  Save this article

Phthalate Exposure and Health-Related Outcomes in Specific Types of Work Environment

Author

Listed:
  • Branislav Kolena

    (Department of Zoology and Anthropology, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia
    These authors contributed equally to this work.)

  • Ida Petrovicova

    (Department of Zoology and Anthropology, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia
    These authors contributed equally to this work.)

  • Tomas Pilka

    (Department of Zoology and Anthropology, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Zuzana Pucherova

    (Department of Ecology and Environmentalistics, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Michal Munk

    (Department of Informatics, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Bohumil Matula

    (Specialized Hospital of St. Zoerardus Zobor, 949 88 Nitra, Slovakia)

  • Viera Vankova

    (Department of Ecology and Environmentalistics, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Peter Petlus

    (Department of Ecology and Environmentalistics, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Zita Jenisova

    (Department of Chemistry, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Zdenka Rozova

    (Department of Ecology and Environmentalistics, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia)

  • Sona Wimmerova

    (Institute of Biophysics, Informatics and Biostatistics, Slovak Medical University, 833 03 Bratislava, Slovakia)

  • Tomas Trnovec

    (Department of Environmental Medicine, Slovak Medical University, 833 03 Bratislava, Slovakia)

Abstract

Many toxic substances in the workplace can modify human health and quality of life and there is still insufficient data on respiratory outcomes in adults exposed to phthalates. The aim of this work was to assess in waste management workers from the Nitra region of Slovakia ( n = 30) the extent of exposure to phthalates and health-related outcomes. Four urinary phthalate metabolites mono(2-ethylhexyl) phthalate (MEHP), monobutyl phthalate (MnBP), monoethyl phthalate (MEP) and monoisononyl phthalate (MiNP) were determined by high-performance liquid chromatography with mass spectrometry (HPLC-MS/MS). Urinary concentration of MEHP was positively associated with ratio of forced expiratory volume in 1 s to forced vital capacity % (FEV 1 /FVC) ( r = 0.431; p = 0.018) and MiNP with fat free mass index (FFMI) ( r = 0.439; p = 0.015). The strongest predictor of pulmonary function was the pack/year index as smoking history that predicted a decrease of pulmonary parameters, the FEV 1 /FVC, % of predicted values of peak expiratory flow (PEF % of PV) and FEV 1 % of PV. Unexpectedly, urinary MEHP and MINP were positively associated with pulmonary function expressed as PEF % of PV and FEV 1 /FVC. We hypothesize that occupational exposure to phthalates estimated from urinary metabolites (MEHP, MiNP) can modify pulmonary function on top of lifestyle factors.

Suggested Citation

  • Branislav Kolena & Ida Petrovicova & Tomas Pilka & Zuzana Pucherova & Michal Munk & Bohumil Matula & Viera Vankova & Peter Petlus & Zita Jenisova & Zdenka Rozova & Sona Wimmerova & Tomas Trnovec, 2014. "Phthalate Exposure and Health-Related Outcomes in Specific Types of Work Environment," IJERPH, MDPI, vol. 11(6), pages 1-12, May.
    • Handle: RePEc:gam:jijerp:v:11:y:2014:i:6:p:5628-5639:d:36467
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/11/6/5628/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/11/6/5628/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jaakkola, J.J.K. & Øie, L. & Nafstad, P. & Botten, G. & Samuelsen, S.O. & Magnus, P., 1999. "Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway," American Journal of Public Health, American Public Health Association, vol. 89(2), pages 188-192.
    2. Jaakkola, J.J.K. & Verkasalo, P.K. & Jaakkola, N., 2000. "Plastic wall materials in the home and respiratory health in young children," American Journal of Public Health, American Public Health Association, vol. 90(5), pages 797-799.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Branislav Kolena & Ida Petrovičová & Miroslava Šidlovská & Henrieta Hlisníková & Lenka Bystričanová & Soňa Wimmerová & Tomáš Trnovec, 2020. "Occupational Hazards and Risks Associated with Phthalates among Slovakian Firefighters," IJERPH, MDPI, vol. 17(7), pages 1-15, April.
    2. Simo P. Porras & Minna Hartonen & Jani Koponen & Katriina Ylinen & Kyösti Louhelainen & Jarkko Tornaeus & Hannu Kiviranta & Tiina Santonen, 2020. "Occupational Exposure of Plastics Workers to Diisononyl Phthalate (DiNP) and Di(2-propylheptyl) Phthalate (DPHP) in Finland," IJERPH, MDPI, vol. 17(6), pages 1-12, March.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Sang-Woo Kim & Jeongho Lee & Soon-Chan Kwon & June-Hee Lee, 2021. "Association between Urinary Phthalate Metabolite Concentration and Atopic Dermatitis in Korean Adolescents Participating in the Third Korean National Environmental Health Survey, 2015–2017," IJERPH, MDPI, vol. 18(5), pages 1-10, February.
    2. W. S. Kwan & D. Nikezic & Vellaisamy A. L. Roy & K. N. Yu, 2020. "Multiple Stressor Effects of Radon and Phthalates in Children: Background Information and Future Research," IJERPH, MDPI, vol. 17(8), pages 1-27, April.
    3. Jing Zhao & Yukari Nagai & Wei Gao & Tao Shen & Youming Fan, 2023. "The Effects of Interior Materials on the Restorativeness of Home Environments," IJERPH, MDPI, vol. 20(14), pages 1-11, July.
    4. Mehzabeen Mannan & Sami G. Al-Ghamdi, 2021. "Indoor Air Quality in Buildings: A Comprehensive Review on the Factors Influencing Air Pollution in Residential and Commercial Structure," IJERPH, MDPI, vol. 18(6), pages 1-25, March.
    5. Hyunok Choi & Norbert Schmidbauer & John Spengler & Carl-Gustaf Bornehag, 2010. "Sources of Propylene Glycol and Glycol Ethers in Air at Home," IJERPH, MDPI, vol. 7(12), pages 1-25, December.
    6. Tin-Tin Win-Shwe & Rie Yanagisawa & Eiko Koike & Hirohisa Takano, 2019. "Memory Function, Neurological, and Immunological Biomarkers in Allergic Asthmatic Mice Intratracheally Exposed to Bisphenol A," IJERPH, MDPI, vol. 16(19), pages 1-16, October.
    7. Constantin C. Bungau & Codruta Bendea & Tudor Bungau & Andrei-Flavius Radu & Marcela Florina Prada & Ioana Francesca Hanga-Farcas & Cosmin Mihai Vesa, 2024. "The Relationship between the Parameters That Characterize a Built Living Space and the Health Status of Its Inhabitants," Sustainability, MDPI, vol. 16(5), pages 1-35, February.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:11:y:2014:i:6:p:5628-5639:d:36467. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.