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Assessment of the Risk of Oral Cancer Incidence in A High-Risk Population and Establishment of A Predictive Model for Oral Cancer Incidence Using A Population-Based Cohort in Taiwan

Author

Listed:
  • Li-Chen Hung

    (Department of Public Health, China Medical University, Taichung 40402, Taiwan
    Department of Healthcare Management, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan
    Authors contributed equally to this work.)

  • Pei-Tseng Kung

    (Department of Healthcare Administration, Asia University, Taichung 41354, Taiwan
    Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan
    Authors contributed equally to this work.)

  • Chi-Hsuan Lung

    (Department of Social Work, National Quemoy University, Quemoy 892, Taiwan)

  • Ming-Hsui Tsai

    (Department of Otolaryngology, China Medical University Hospital, Taichung 40447, Taiwan)

  • Shih-An Liu

    (Department of ENT, Taichung Veterans General Hospital, Taichung 40705, Taiwan)

  • Li-Ting Chiu

    (Department of Health Services Administration, China Medical University, Taichung 40402, Taiwan)

  • Kuang-Hua Huang

    (Department of Health Services Administration, China Medical University, Taichung 40402, Taiwan
    Authors contributed equally to this work.)

  • Wen-Chen Tsai

    (Department of Health Services Administration, China Medical University, Taichung 40402, Taiwan
    Authors contributed equally to this work.)

Abstract

We aimed to assess the risk of oral cancer incidence in a high-risk population, establish a predictive model for oral cancer among these high-risk individuals, and assess the predictive ability of the constructed model. Individuals aged ≥30 years who had a habit of smoking or betel nut chewing and had undergone oral cancer screening in 2010 or 2011 were selected as study subjects. The incidence of oral cancer among the subjects at the end of 2014 was determined. The annual oral cancer incidence among individuals with a positive screening result was 624 per 100,000 persons, which was 6.5 times that of the annual oral cancer incidence among all individuals screened. Male sex, aged 45–64 years, divorce, low educational level, presence of diabetes, presence of other cancers, high comorbidity severity, a habit of smoking or betel nut chewing, and low monthly salary were high-risk factors for oral cancer incidence ( p < 0.05). The area under the curve of the predictive model for oral cancer incidence was 0.73, which indicated a good predictive ability. Therefore, the oral cancer screening policy for the high-risk population with a habit of smoking and/or betel nut chewing is beneficial for the early diagnosis of oral cancer.

Suggested Citation

  • Li-Chen Hung & Pei-Tseng Kung & Chi-Hsuan Lung & Ming-Hsui Tsai & Shih-An Liu & Li-Ting Chiu & Kuang-Hua Huang & Wen-Chen Tsai, 2020. "Assessment of the Risk of Oral Cancer Incidence in A High-Risk Population and Establishment of A Predictive Model for Oral Cancer Incidence Using A Population-Based Cohort in Taiwan," IJERPH, MDPI, vol. 17(2), pages 1-15, January.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:2:p:665-:d:310940
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    References listed on IDEAS

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    1. Oron Vanunu & Oded Magger & Eytan Ruppin & Tomer Shlomi & Roded Sharan, 2010. "Associating Genes and Protein Complexes with Disease via Network Propagation," PLOS Computational Biology, Public Library of Science, vol. 6(1), pages 1-9, January.
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    Cited by:

    1. Muhammad Ikbal & Yen-Wen Shen & Wen-Miin Liang & Trong-Neng Wu & Jui-Ting Hsu & Lih-Jyh Fuh, 2022. "Outpatient Dental Treatment Expenditure for Patients with Oromaxillofacial Cancer: A Cohort Study in Taiwan," IJERPH, MDPI, vol. 19(3), pages 1-12, January.
    2. Ying-Cheng Chen & Cheng-Hsun Chuang & Ming-Hong Hsieh & Han-Wei Yeh & Shun-Fa Yang & Chiao-Wen Lin & Ying-Tung Yeh & Jing-Yang Huang & Pei-Lun Liao & Chi-Ho Chan & Chao-Bin Yeh, 2021. "Risk of Mortality and Readmission among Patients with Pelvic Fracture and Urinary Tract Infection: A Population-Based Cohort Study," IJERPH, MDPI, vol. 18(9), pages 1-10, May.
    3. Parvaneh Badri & Hollis Lai & Seema Ganatra & Vickie Baracos & Maryam Amin, 2022. "Factors Associated with Oral Cancerous and Precancerous Lesions in an Underserved Community: A Cross-Sectional Study," IJERPH, MDPI, vol. 19(3), pages 1-12, January.
    4. Shih-Yung Su, 2022. "Evaluation of Nationwide Oral Mucosal Screening Program for Oral Cancer Mortality among Men in Taiwan," IJERPH, MDPI, vol. 19(21), pages 1-12, November.

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