IDEAS home Printed from https://ideas.repec.org/a/eee/rensus/v152y2021ics1364032121008856.html
   My bibliography  Save this article

Powerful tools for productivity improvements in microalgal production

Author

Listed:
  • Sun, Han
  • Wu, Tao
  • Chen, Stephenie Hiu Yuet
  • Ren, Yuanyuan
  • Yang, Shufang
  • Huang, Junchao
  • Mou, Haijin
  • Chen, Feng

Abstract

Technology for microalgae cultivation has potential to maximize biomass generation to production process and economic viability of microalgal production. Powerful tools that increase the production and value of microalgae are therefore of great significance. In this review, valid approaches involved in strain screening, microalgal cultivation, cell harvesting and disruption are discussed with regards to productivity improvements and energy efficiency. Particularly, current research in kinetic models, metabolic flux analysis and genetic tools are considered. Kinetic models of nutrient, light, temperature and cell quota to increase the biomass concentration and targeted products are discussed. Metabolic flux analysis, especially GC–MS-based 13C-metabolic flux analysis is discussed to describe how the central carbon flux to targeted products can be precisely and rapidly engineered. This approach is exemplified by Chromochloris zofingiensis under batch and fed-batch cultures. Molecular approaches including gene silencing methods and CRISPR–Cas9 are also discussed as these provide powerful tools for enhanced production of biomass and associated lipids and carotenoids. Finally, the huge potential of combined applications of the described tools are discussed. A better understanding of cell behavior in response to these tools will provide the means to improve microalgal production at a competitive cost.

Suggested Citation

  • Sun, Han & Wu, Tao & Chen, Stephenie Hiu Yuet & Ren, Yuanyuan & Yang, Shufang & Huang, Junchao & Mou, Haijin & Chen, Feng, 2021. "Powerful tools for productivity improvements in microalgal production," Renewable and Sustainable Energy Reviews, Elsevier, vol. 152(C).
    • Handle: RePEc:eee:rensus:v:152:y:2021:i:c:s1364032121008856
    DOI: 10.1016/j.rser.2021.111609
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S1364032121008856
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.rser.2021.111609?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Esakkimuthu, Sivakumar & Krishnamurthy, Venkatesan & Wang, Shuang & Hu, Xun & K, Swaminathan & Abomohra, Abd El-Fatah, 2020. "Application of p-coumaric acid for extraordinary lipid production in Tetradesmus obliquus: A sustainable approach towards enhanced biodiesel production," Renewable Energy, Elsevier, vol. 157(C), pages 368-376.
    2. Chen, Hui & Wang, Jie & Zheng, Yanli & Zhan, Jiao & He, Chenliu & Wang, Qiang, 2018. "Algal biofuel production coupled bioremediation of biomass power plant wastes based on Chlorella sp. C2 cultivation," Applied Energy, Elsevier, vol. 211(C), pages 296-305.
    3. Li, Pengfei & Sun, Xin & Sun, Zhe & Huang, Feng & Wei, Wenqian & Liu, Xingshe & Liu, Yongjun & Deng, Linyu & Cheng, Zhiwen, 2021. "Biochemical and genetic changes revealing the enhanced lipid accumulation in Desmodesmus sp. mutated by atmospheric and room temperature plasma," Renewable Energy, Elsevier, vol. 172(C), pages 368-381.
    4. Halim, Ronald & Harun, Razif & Danquah, Michael K. & Webley, Paul A., 2012. "Microalgal cell disruption for biofuel development," Applied Energy, Elsevier, vol. 91(1), pages 116-121.
    5. Randor Radakovits & Robert E. Jinkerson & Susan I. Fuerstenberg & Hongseok Tae & Robert E. Settlage & Jeffrey L. Boore & Matthew C. Posewitz, 2012. "Draft genome sequence and genetic transformation of the oleaginous alga Nannochloropsis gaditana," Nature Communications, Nature, vol. 3(1), pages 1-11, January.
    6. Mata, Teresa M. & Martins, António A. & Caetano, Nidia. S., 2010. "Microalgae for biodiesel production and other applications: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 14(1), pages 217-232, January.
    7. Zheng, Yubin & Li, Tingting & Yu, Xiaochen & Bates, Philip D. & Dong, Tao & Chen, Shulin, 2013. "High-density fed-batch culture of a thermotolerant microalga Chlorella sorokiniana for biofuel production," Applied Energy, Elsevier, vol. 108(C), pages 281-287.
    8. Yuan, Shuo & Zhou, Xinping & Chen, Ranchi & Song, Bao, 2014. "Study on modelling microalgae growth in nitrogen-limited culture system for estimating biomass productivity," Renewable and Sustainable Energy Reviews, Elsevier, vol. 34(C), pages 525-535.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Goh, Brandon Han Hoe & Ong, Hwai Chyuan & Cheah, Mei Yee & Chen, Wei-Hsin & Yu, Kai Ling & Mahlia, Teuku Meurah Indra, 2019. "Sustainability of direct biodiesel synthesis from microalgae biomass: A critical review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 107(C), pages 59-74.
    2. Yuan, Shuo & Hu, Jinrun & Liu, Zhiyuan & Hong, Yuanzhuo & Wang, Xianyong, 2020. "Modeling microalgae growth in continuous culture: Parameters analysis and temperature dependence," Energy, Elsevier, vol. 195(C).
    3. Ayesha Aslam & Sumaira Rasul & Ali Bahadar & Nazia Hossain & Muhammad Saleem & Sabir Hussain & Lubna Rasool & Hamid Manzoor, 2021. "Effect of Micronutrient and Hormone on Microalgae Growth Assessment for Biofuel Feedstock," Sustainability, MDPI, vol. 13(9), pages 1-20, April.
    4. Saddam H. Al-lwayzy & Talal Yusaf & Raed A. Al-Juboori, 2014. "Biofuels from the Fresh Water Microalgae Chlorella vulgaris (FWM-CV) for Diesel Engines," Energies, MDPI, vol. 7(3), pages 1-23, March.
    5. D’Alessandro, Emmanuel B. & Antoniosi Filho, Nelson R., 2016. "Concepts and studies on lipid and pigments of microalgae: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 58(C), pages 832-841.
    6. Islam, Muhammad Aminul & Heimann, Kirsten & Brown, Richard J., 2017. "Microalgae biodiesel: Current status and future needs for engine performance and emissions," Renewable and Sustainable Energy Reviews, Elsevier, vol. 79(C), pages 1160-1170.
    7. Wang, Songmei & Zhu, Johnny & Dai, Lingmei & Zhao, Xuebing & Liu, Dehua & Du, Wei, 2016. "A novel process on lipid extraction from microalgae for biodiesel production," Energy, Elsevier, vol. 115(P1), pages 963-968.
    8. Masoud Derakhshandeh & Tahir Atici & Umran Tezcan UN, 2019. "Lipid extraction from microalgae Chlorella and Synechocystis sp. using glass microparticles as disruption enhancer," Energy & Environment, , vol. 30(8), pages 1341-1355, December.
    9. Adeniyi, Oladapo Martins & Azimov, Ulugbek & Burluka, Alexey, 2018. "Algae biofuel: Current status and future applications," Renewable and Sustainable Energy Reviews, Elsevier, vol. 90(C), pages 316-335.
    10. Marwa G. Saad & Noura S. Dosoky & Mohamed S. Zoromba & Hesham M. Shafik, 2019. "Algal Biofuels: Current Status and Key Challenges," Energies, MDPI, vol. 12(10), pages 1-22, May.
    11. Dong, Tao & Knoshaug, Eric P. & Pienkos, Philip T. & Laurens, Lieve M.L., 2016. "Lipid recovery from wet oleaginous microbial biomass for biofuel production: A critical review," Applied Energy, Elsevier, vol. 177(C), pages 879-895.
    12. Menegazzo, Mariana Lara & Fonseca, Gustavo Graciano, 2019. "Biomass recovery and lipid extraction processes for microalgae biofuels production: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 107(C), pages 87-107.
    13. Zhang, Yi & Kong, Xiaoying & Wang, Zhongming & Sun, Yongming & Zhu, Shunni & Li, Lianhua & Lv, Pengmei, 2018. "Optimization of enzymatic hydrolysis for effective lipid extraction from microalgae Scenedesmus sp," Renewable Energy, Elsevier, vol. 125(C), pages 1049-1057.
    14. Darvehei, Pooya & Bahri, Parisa A. & Moheimani, Navid R., 2018. "Model development for the growth of microalgae: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 97(C), pages 233-258.
    15. de Jesus, Sérgio S. & Ferreira, Gabriela F. & Moreira, Larissa S. & Filho, Rubens Maciel, 2020. "Biodiesel production from microalgae by direct transesterification using green solvents," Renewable Energy, Elsevier, vol. 160(C), pages 1283-1294.
    16. Terigar, Beatrice G. & Theegala, Chandra S., 2014. "Investigating the interdependence between cell density, biomass productivity, and lipid productivity to maximize biofuel feedstock production from outdoor microalgal cultures," Renewable Energy, Elsevier, vol. 64(C), pages 238-243.
    17. Baudry, Gino & Delrue, Florian & Legrand, Jack & Pruvost, Jérémy & Vallée, Thomas, 2017. "The challenge of measuring biofuel sustainability: A stakeholder-driven approach applied to the French case," Renewable and Sustainable Energy Reviews, Elsevier, vol. 69(C), pages 933-947.
    18. Maity, Jyoti Prakash & Hou, Chia-Peng & Majumder, Dip & Bundschuh, Jochen & Kulp, Thomas R. & Chen, Chien-Yen & Chuang, Lu-Te & Nathan Chen, Ching-Nen & Jean, Jiin-Shuh & Yang, Tsui-Chu & Chen, Chien-, 2014. "The production of biofuel and bioelectricity associated with wastewater treatment by green algae," Energy, Elsevier, vol. 78(C), pages 94-103.
    19. Patel, Akash & Gami, Bharat & Patel, Pankaj & Patel, Beena, 2017. "Microalgae: Antiquity to era of integrated technology," Renewable and Sustainable Energy Reviews, Elsevier, vol. 71(C), pages 535-547.
    20. Bergthorson, Jeffrey M. & Thomson, Murray J., 2015. "A review of the combustion and emissions properties of advanced transportation biofuels and their impact on existing and future engines," Renewable and Sustainable Energy Reviews, Elsevier, vol. 42(C), pages 1393-1417.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:rensus:v:152:y:2021:i:c:s1364032121008856. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/wps/find/journaldescription.cws_home/600126/description#description .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.