IDEAS home Printed from https://ideas.repec.org/a/eee/phsmap/v626y2023ics037843712300626x.html
   My bibliography  Save this article

Mathematical and informational tools for classifying blood glucose signals - a pilot study

Author

Listed:
  • Amadio, Ariel
  • Rey, Andrea
  • Legnani, Walter
  • Blesa, Manuel García
  • Bonini, Cristian
  • Otero, Dino

Abstract

A survey campaign was carried out on the dynamics of blood glucose measured through interstitial sensors of relative recent diffusion in the market. These sensors generated time series that were labeled according to medical diagnosis in diabetics and non-diabetics, and that constituted the data core of the classification models. Based on the calculation of the distribution of ordinal patterns of the time series, the corresponding points in the entropy-complexity causal plane were located. Moreover, the transition matrices of these ordinal patterns (OPTMs) were calculated in order to find the proximity using the Manhattan distance of every OPTM with respect to the mean of each group, associating the corresponding signal to each class. On the other hand, the Frobenius norm of every OPTM and the norm of its stationary vector were computed given different values for the considered classes. The effect of repeated values in a signal was also analyzed. Notable differences were obtained in the properties of the OPTMs of each class. In another sense, it is shown that diabetes is a disease that reduces the entropy of the temporal evolution of blood glucose in well-defined time periods and presents values of complexity significantly higher than those obtained in subjects without diabetes. The selected alternatives coincide in detecting patients positively diagnosed with Type II Diabetes Mellitus. The calculations on the OPTMs show the correlation among patterns of the signals. At the same time, in the entropy-complexity plane, the considered groups were located in well-defined regions showing the differentiating power of these information measures and indicating variations in the dynamics of the biological system when diabetes is present. With the four mathematical tools selected and the dynamical characterization given by the causal plane, it was possible to define an index that clearly differentiates the classes under study.

Suggested Citation

  • Amadio, Ariel & Rey, Andrea & Legnani, Walter & Blesa, Manuel García & Bonini, Cristian & Otero, Dino, 2023. "Mathematical and informational tools for classifying blood glucose signals - a pilot study," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 626(C).
    • Handle: RePEc:eee:phsmap:v:626:y:2023:i:c:s037843712300626x
    DOI: 10.1016/j.physa.2023.129071
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S037843712300626X
    Download Restriction: Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000
    File URL: https://libkey.io/10.1016/j.physa.2023.129071?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Osvaldo Rosso & Felipe Olivares & Luciano Zunino & Luciana Micco & André Aquino & Angelo Plastino & Hilda Larrondo, 2013. "Characterization of chaotic maps using the permutation Bandt-Pompe probability distribution," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 86(4), pages 1-13, April.
    2. Mateos, Diego M. & Gómez-Ramírez, Jaime & Rosso, Osvaldo A., 2021. "Using time causal quantifiers to characterize sleep stages," Chaos, Solitons & Fractals, Elsevier, vol. 146(C).
    3. Martin, M.T. & Plastino, A. & Rosso, O.A., 2006. "Generalized statistical complexity measures: Geometrical and analytical properties," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 369(2), pages 439-462.
    4. Borges, João B. & Ramos, Heitor S. & Mini, Raquel A.F. & Rosso, Osvaldo A. & Frery, Alejandro C. & Loureiro, Antonio A.F., 2019. "Learning and distinguishing time series dynamics via ordinal patterns transition graphs," Applied Mathematics and Computation, Elsevier, vol. 362(C), pages 1-1.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mateos, Diego M. & Zozor, Steeve & Olivares, Felipe, 2020. "Contrasting stochasticity with chaos in a permutation Lempel–Ziv complexity — Shannon entropy plane," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 554(C).
    2. Eduarda T. C. Chagas & Marcelo Queiroz‐Oliveira & Osvaldo A. Rosso & Heitor S. Ramos & Cristopher G. S. Freitas & Alejandro C. Frery, 2022. "White Noise Test from Ordinal Patterns in the Entropy–Complexity Plane," International Statistical Review, International Statistical Institute, vol. 90(2), pages 374-396, August.
    3. Aquino, Andre L.L. & Ramos, Heitor S. & Frery, Alejandro C. & Viana, Leonardo P. & Cavalcante, Tamer S.G. & Rosso, Osvaldo A., 2017. "Characterization of electric load with Information Theory quantifiers," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 465(C), pages 277-284.
    4. Bariviera, Aurelio F. & Font-Ferrer, Alejandro & Sorrosal-Forradellas, M. Teresa & Rosso, Osvaldo A., 2019. "An information theory perspective on the informational efficiency of gold price," The North American Journal of Economics and Finance, Elsevier, vol. 50(C).
    5. Fernandes, Leonardo H.S. & de Araujo, Fernando H.A. & Tabak, Benjamin M., 2021. "Insights from the (in)efficiency of Chinese sectoral indices during COVID-19," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 578(C).
    6. Aurelio F. Bariviera & Luciano Zunino & Osvaldo A. Rosso, 2016. "Crude Oil Market And Geopolitical Events: An Analysis Based On Information-Theory-Based Quantifiers," Fuzzy Economic Review, International Association for Fuzzy-set Management and Economy (SIGEF), vol. 21(1), pages 41-51, May.
    7. Mastroeni, Loretta & Mazzoccoli, Alessandro & Vellucci, Pierluigi, 2024. "Wavelet entropy and complexity–entropy curves approach for energy commodity price predictability amid the transition to alternative energy sources," Chaos, Solitons & Fractals, Elsevier, vol. 184(C).
    8. Gonçalves, Bruna Amin & Carpi, Laura & Rosso, Osvaldo A. & Ravetti, Martín G., 2016. "Time series characterization via horizontal visibility graph and Information Theory," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 464(C), pages 93-102.
    9. Montani, Fernando & Deleglise, Emilia B. & Rosso, Osvaldo A., 2014. "Efficiency characterization of a large neuronal network: A causal information approach," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 401(C), pages 58-70.
    10. F. J. Alonso & M. C. Bueso & J. M. Angulo, 2016. "Dependence Assessment Based on Generalized Relative Complexity: Application to Sampling Network Design," Methodology and Computing in Applied Probability, Springer, vol. 18(3), pages 921-933, September.
    11. Katchanov, Yurij L. & Markova, Yulia V., 2022. "Dynamics of senses of new physics discourse: Co-keywords analysis," Journal of Informetrics, Elsevier, vol. 16(1).
    12. Spichak, David & Kupetsky, Audrey & Aragoneses, Andrés, 2021. "Characterizing complexity of non-invertible chaotic maps in the Shannon–Fisher information plane with ordinal patterns," Chaos, Solitons & Fractals, Elsevier, vol. 142(C).
    13. Calbet, Xavier & López-Ruiz, Ricardo, 2007. "Extremum complexity distribution of a monodimensional ideal gas out of equilibrium," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 382(2), pages 523-530.
    14. Fernandes, Leonardo H.S. & de Araújo, Fernando H.A. & Silva, Igor E.M. & Neto, Jusie S.P., 2021. "Macroeconophysics indicator of economic efficiency," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 573(C).
    15. Gu, Danlei & Lin, Aijing & Lin, Guancen, 2022. "Sleep and cardiac signal processing using improved multivariate partial compensated transfer entropy based on non-uniform embedding," Chaos, Solitons & Fractals, Elsevier, vol. 159(C).
    16. Aurelio Fernandez Bariviera & María Belén Guercio & Lisana B. Martinez & Osvaldo A. Rosso, 2015. "The (in)visible hand in the Libor market: an information theory approach," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 88(8), pages 1-9, August.
    17. Araújo, Felipe & Bastos, Lucas & Medeiros, Iago & Rosso, Osvaldo A. & Aquino, Andre L.L. & Rosário, Denis & Cerqueira, Eduardo, 2023. "Characterization of human mobility based on Information Theory quantifiers," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 609(C).
    18. Mao, Xuegeng & Shang, Pengjian & Xu, Meng & Peng, Chung-Kang, 2020. "Measuring time series based on multiscale dispersion Lempel–Ziv complexity and dispersion entropy plane," Chaos, Solitons & Fractals, Elsevier, vol. 137(C).
    19. Bariviera, Aurelio F. & Guercio, M. Belén & Martinez, Lisana B. & Rosso, Osvaldo A., 2016. "Libor at crossroads: Stochastic switching detection using information theory quantifiers," Chaos, Solitons & Fractals, Elsevier, vol. 88(C), pages 172-182.
    20. Xu, Meng & Shang, Pengjian & Zhang, Sheng, 2021. "Multiscale Rényi cumulative residual distribution entropy: Reliability analysis of financial time series," Chaos, Solitons & Fractals, Elsevier, vol. 143(C).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:phsmap:v:626:y:2023:i:c:s037843712300626x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/physica-a-statistical-mechpplications/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.