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Entropy generation approach to cell systems

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  • Lucia, Umberto

Abstract

Cells can be regarded as engines that execute a series of chemical reactions. A malignant cell, that is, a cancerous cell, can be described as an open complex dynamic and self-organising system. The entropy generation approach has been used to evaluate the stationary states for cells in relation to the global results of the cell biophysical and biochemical processes. Then, an entropy generation approach can been used to evaluate malignant behaviour in terms of thermal, chemical and transport processes. A numerical evaluation of the mean value of the entropy generation for cancer is developed. A possible therapy against cancer has been suggested by using molecular thermalisation.

Suggested Citation

  • Lucia, Umberto, 2014. "Entropy generation approach to cell systems," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 406(C), pages 1-11.
    • Handle: RePEc:eee:phsmap:v:406:y:2014:i:c:p:1-11
    DOI: 10.1016/j.physa.2014.03.050
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    References listed on IDEAS

    as
    1. Lucia, Umberto, 2014. "Entropy generation: Minimum inside and maximum outside," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 396(C), pages 61-65.
    2. Lucia, Umberto, 2013. "Stationary open systems: A brief review on contemporary theories on irreversibility," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(5), pages 1051-1062.
    3. Lucia, Umberto, 2013. "Thermodynamic paths and stochastic order in open systems," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(18), pages 3912-3919.
    4. Jarungthammachote, Sompop, 2010. "Entropy generation analysis for fully developed laminar convection in hexagonal duct subjected to constant heat flux," Energy, Elsevier, vol. 35(12), pages 5374-5379.
    5. Hajmohammadi, M.R. & Eskandari, H. & Saffar-Avval, M. & Campo, A., 2013. "A new configuration of bend tubes for compound optimization of heat and fluid flow," Energy, Elsevier, vol. 62(C), pages 418-424.
    6. Lucia, Umberto, 2013. "Carnot efficiency: Why?," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(17), pages 3513-3517.
    7. Lucia, Umberto, 2007. "Irreversible entropy variation and the problem of the trend to equilibrium," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 376(C), pages 289-292.
    8. Lucia, U. & Maino, G., 2002. "Thermodynamical analysis of the dynamics of tumor interaction with the host immune system," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 313(3), pages 569-577.
    9. Lucia, Umberto, 2012. "Irreversibility in biophysical and biochemical engineering," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 391(23), pages 5997-6007.
    10. Lucia, Umberto, 2009. "Irreversibility, entropy and incomplete information," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 388(19), pages 4025-4033.
    11. Lucia, Umberto, 2013. "Thermodynamics and cancer stationary states," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(17), pages 3648-3653.
    12. Lucia, U., 2012. "Maximum or minimum entropy generation for open systems?," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 391(12), pages 3392-3398.
    13. Lucia, Umberto, 2010. "Maximum entropy generation and κ-exponential model," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 389(21), pages 4558-4563.
    14. Lucia, Umberto, 2008. "Statistical approach of the irreversible entropy variation," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 387(14), pages 3454-3460.
    15. Lucia, Umberto, 2014. "Entropy generation and the Fokker–Planck equation," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 393(C), pages 256-260.
    16. Lucia, Umberto, 2014. "Overview on fuel cells," Renewable and Sustainable Energy Reviews, Elsevier, vol. 30(C), pages 164-169.
    17. Wei, Shuhuan & Chen, Lingen & Sun, Fengrui, 2009. "The area-point constructal optimization for discrete variable cross-section conducting path," Applied Energy, Elsevier, vol. 86(7-8), pages 1111-1118, July.
    18. Lucia, Umberto & Sciubba, Enrico, 2013. "From Lotka to the entropy generation approach," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(17), pages 3634-3639.
    19. Lucia, Umberto, 2013. "Entropy and exergy in irreversible renewable energy systems," Renewable and Sustainable Energy Reviews, Elsevier, vol. 20(C), pages 559-564.
    20. Lucia, Umberto, 2014. "Transport processes in biological systems: Tumoral cells and human brain," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 393(C), pages 327-336.
    21. Lucia, Umberto, 2013. "Exergy flows as bases of constructal law," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(24), pages 6284-6287.
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    1. Lucia, Umberto, 2014. "Thermodynamic approach to nano-properties of cell membrane," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 407(C), pages 185-191.
    2. Lucia, Umberto, 2014. "Entropy generation and cell growth with comments for a thermodynamic anticancer approach," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 406(C), pages 107-118.
    3. Lucia, Umberto & Ponzetto, Antonio & Deisboeck, Thomas S., 2015. "A thermodynamic approach to the ‘mitosis/apoptosis’ ratio in cancer," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 436(C), pages 246-255.
    4. González-Solís, José Luis & Guizar-Ruiz, Juan Ignacio & Martínez-Espinosa, Juan Carlos & Martínez-Zerega, Brenda Esmeralda & Juárez-López, Héctor Alfonso & Vargas-Rodríguez, Héctor & Gallegos-Infante,, 2016. "Cancer detection based on Raman spectra super-paramagnetic clustering," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 455(C), pages 52-64.
    5. Lucia, Umberto & Ponzetto, Antonio, 2017. "Some thermodynamic considerations on low frequency electromagnetic waves effects on cancer invasion and metastasis," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 467(C), pages 289-295.
    6. Umberto Lucia & Giulia Grisolia, 2018. "Cyanobacteria and Microalgae : Thermoeconomic Considerations in Biofuel Production," Energies, MDPI, vol. 11(1), pages 1-16, January.
    7. Umberto Lucia, 2014. "The Gouy-Stodola Theorem in Bioenergetic Analysis of Living Systems (Irreversibility in Bioenergetics of Living Systems)," Energies, MDPI, vol. 7(9), pages 1-23, September.
    8. Lucia, Umberto & Ponzetto, Antonio & Deisboeck, Thomas S., 2016. "Investigating the impact of electromagnetic fields on human cells: A thermodynamic perspective," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 443(C), pages 42-48.
    9. Lucia, Umberto, 2016. "Considerations on non equilibrium thermodynamics of interactions," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 447(C), pages 314-319.

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