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Change point models for cognitive tests using semi-parametric maximum likelihood

Author

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  • van den Hout, Ardo
  • Muniz-Terrera, Graciela
  • Matthews, Fiona E.

Abstract

Random-effects change point models are formulated for longitudinal data obtained from cognitive tests. The conditional distribution of the response variable in a change point model is often assumed to be normal even if the response variable is discrete and shows ceiling effects. For the sum score of a cognitive test, the binomial and the beta-binomial distributions are presented as alternatives to the normal distribution. Smooth shapes for the change point models are imposed. Estimation is by marginal maximum likelihood where a parametric population distribution for the random change point is combined with a non-parametric mixing distribution for other random effects. An extension to latent class modelling is possible in case some individuals do not experience a change in cognitive ability. The approach is illustrated using data from a longitudinal study of Swedish octogenarians and nonagenarians that began in 1991. Change point models are applied to investigate cognitive change in the years before death.

Suggested Citation

  • van den Hout, Ardo & Muniz-Terrera, Graciela & Matthews, Fiona E., 2013. "Change point models for cognitive tests using semi-parametric maximum likelihood," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 684-698.
  • Handle: RePEc:eee:csdana:v:57:y:2013:i:1:p:684-698
    DOI: 10.1016/j.csda.2012.07.024
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    References listed on IDEAS

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    2. Chenghao Chu & Ying Zhang & Wanzhu Tu, 2020. "Stochastic functional estimates in longitudinal models with interval‐censored anchoring events," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 47(3), pages 638-661, September.

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