IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v170y2022ics0167947322000184.html
   My bibliography  Save this article

A fast approximate EM algorithm for joint models of survival and multivariate longitudinal data

Author

Listed:
  • Murray, James
  • Philipson, Pete

Abstract

Joint models are an increasingly popular way to characterise the relationship between one or more longitudinal responses and an event of interest. However, for multivariate joint models the increased dimensionality and complexity of random effects present in the model specification are commensurate with increased computing time, hampering the implementation of many classic approaches. An approximate EM algorithm which ameliorates the so-called ‘curse of dimensionality’ is developed. The scaleability and accuracy of the proposed method are demonstrated via two simulation studies and applied to data arising from two clinical trials in the disease areas of cirrhosis and Alzheimer's disease, each with three biomarkers.

Suggested Citation

  • Murray, James & Philipson, Pete, 2022. "A fast approximate EM algorithm for joint models of survival and multivariate longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 170(C).
  • Handle: RePEc:eee:csdana:v:170:y:2022:i:c:s0167947322000184
    DOI: 10.1016/j.csda.2022.107438
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167947322000184
    Download Restriction: Full text for ScienceDirect subscribers only.

    File URL: https://libkey.io/10.1016/j.csda.2022.107438?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Rizopoulos, Dimitris, 2016. "The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data Using MCMC," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 72(i07).
    2. Philipson, Pete & Hickey, Graeme L. & Crowther, Michael J. & Kolamunnage-Dona, Ruwanthi, 2020. "Faster Monte Carlo estimation of joint models for time-to-event and multivariate longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 151(C).
    3. Hongsheng Dai & Jianxin Pan, 2018. "Joint Modelling of Survival and Longitudinal Data with Informative Observation Times," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 45(3), pages 571-589, September.
    4. Bernhardt, Paul W. & Zhang, Daowen & Wang, Huixia Judy, 2015. "A fast EM algorithm for fitting joint models of a binary response and multiple longitudinal covariates subject to detection limits," Computational Statistics & Data Analysis, Elsevier, vol. 85(C), pages 37-53.
    5. Bates, Douglas & Mächler, Martin & Bolker, Ben & Walker, Steve, 2015. "Fitting Linear Mixed-Effects Models Using lme4," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 67(i01).
    6. Yue Wang & Joseph G. Ibrahim & Hongtu Zhu, 2020. "Partial least squares for functional joint models with applications to the Alzheimer's disease neuroimaging initiative study," Biometrics, The International Biometric Society, vol. 76(4), pages 1109-1119, December.
    7. Peng, Mengjiao & Xiang, Liming & Wang, Shanshan, 2018. "Semiparametric regression analysis of clustered survival data with semi-competing risks," Computational Statistics & Data Analysis, Elsevier, vol. 124(C), pages 53-70.
    8. Allison K.C. Furgal & Ananda Sen & Jeremy M.G. Taylor, 2019. "Review and Comparison of Computational Approaches for Joint Longitudinal and Time‐to‐Event Models," International Statistical Review, International Statistical Institute, vol. 87(2), pages 393-418, August.
    9. Rizopoulos, Dimitris, 2012. "Fast fitting of joint models for longitudinal and event time data using a pseudo-adaptive Gaussian quadrature rule," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 491-501.
    10. Baghishani, Hossein & Mohammadzadeh, Mohsen, 2012. "Asymptotic normality of posterior distributions for generalized linear mixed models," Journal of Multivariate Analysis, Elsevier, vol. 111(C), pages 66-77.
    11. Lisa M. McCrink & Adele H. Marshall & Karen J. Cairns, 2013. "Advances in Joint Modelling: A Review of Recent Developments with Application to the Survival of End Stage Renal Disease Patients," International Statistical Review, International Statistical Institute, vol. 81(2), pages 249-269, August.
    12. Dimitris Rizopoulos & Geert Verbeke & Emmanuel Lesaffre, 2009. "Fully exponential Laplace approximations for the joint modelling of survival and longitudinal data," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 71(3), pages 637-654, June.
    13. Khurshid Alam & Arnab Maity & Sanjoy K. Sinha & Dimitris Rizopoulos & Abdus Sattar, 2021. "Joint modeling of longitudinal continuous, longitudinal ordinal, and time-to-event outcomes," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(1), pages 64-90, January.
    14. Hwang, Yi-Ting & Tsai, Hao-Yun & Chang, Yeu-Jhy & Kuo, Hsun-Chih & Wang, Chun-Chao, 2011. "The joint model of the logistic model and linear random effect model -- An application to predict orthostatic hypertension for subacute stroke patients," Computational Statistics & Data Analysis, Elsevier, vol. 55(1), pages 914-923, January.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Murray, James & Philipson, Pete, 2023. "Fast estimation for generalised multivariate joint models using an approximate EM algorithm," Computational Statistics & Data Analysis, Elsevier, vol. 187(C).
    2. Zhang, Zili & Charalambous, Christiana & Foster, Peter, 2023. "A Gaussian copula joint model for longitudinal and time-to-event data with random effects," Computational Statistics & Data Analysis, Elsevier, vol. 181(C).
    3. Zhang, Cuihong & Ning, Jing & Cai, Jianwen & Squires, James E. & Belle, Steven H. & Li, Ruosha, 2024. "Dynamic risk score modeling for multiple longitudinal risk factors and survival," Computational Statistics & Data Analysis, Elsevier, vol. 189(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Murray, James & Philipson, Pete, 2023. "Fast estimation for generalised multivariate joint models using an approximate EM algorithm," Computational Statistics & Data Analysis, Elsevier, vol. 187(C).
    2. Zhang, Zili & Charalambous, Christiana & Foster, Peter, 2023. "A Gaussian copula joint model for longitudinal and time-to-event data with random effects," Computational Statistics & Data Analysis, Elsevier, vol. 181(C).
    3. Zhang, Cuihong & Ning, Jing & Cai, Jianwen & Squires, James E. & Belle, Steven H. & Li, Ruosha, 2024. "Dynamic risk score modeling for multiple longitudinal risk factors and survival," Computational Statistics & Data Analysis, Elsevier, vol. 189(C).
    4. Philipson, Pete & Hickey, Graeme L. & Crowther, Michael J. & Kolamunnage-Dona, Ruwanthi, 2020. "Faster Monte Carlo estimation of joint models for time-to-event and multivariate longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 151(C).
    5. Bernhardt, Paul W. & Zhang, Daowen & Wang, Huixia Judy, 2015. "A fast EM algorithm for fitting joint models of a binary response and multiple longitudinal covariates subject to detection limits," Computational Statistics & Data Analysis, Elsevier, vol. 85(C), pages 37-53.
    6. Toshihiro Misumi, 2022. "Joint modeling for longitudinal covariate and binary outcome via h-likelihood," Statistical Methods & Applications, Springer;Società Italiana di Statistica, vol. 31(5), pages 1225-1243, December.
    7. JANSSENS, Jochen & DE CORTE, Annelies & SÖRENSEN, Kenneth, 2016. "Water distribution network design optimisation with respect to reliability," Working Papers 2016007, University of Antwerp, Faculty of Business and Economics.
    8. Raymond Hernandez & Elizabeth A. Pyatak & Cheryl L. P. Vigen & Haomiao Jin & Stefan Schneider & Donna Spruijt-Metz & Shawn C. Roll, 2021. "Understanding Worker Well-Being Relative to High-Workload and Recovery Activities across a Whole Day: Pilot Testing an Ecological Momentary Assessment Technique," IJERPH, MDPI, vol. 18(19), pages 1-17, October.
    9. Christopher Hassall & Michael Nisbet & Evan Norcliffe & He Wang, 2024. "The Potential Health Benefits of Urban Tree Planting Suggested through Immersive Environments," Land, MDPI, vol. 13(3), pages 1-12, February.
    10. Jie Zhao & Ji Chen & Damien Beillouin & Hans Lambers & Yadong Yang & Pete Smith & Zhaohai Zeng & Jørgen E. Olesen & Huadong Zang, 2022. "Global systematic review with meta-analysis reveals yield advantage of legume-based rotations and its drivers," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    11. Elisabeth Beckmann & Lukas Olbrich & Joseph Sakshaug, 2024. "Multivariate assessment of interviewer-related errors in a cross-national economic survey (Lukas Olbrich, Elisabeth Beckmann, Joseph W. Sakshaug)," Working Papers 253, Oesterreichische Nationalbank (Austrian Central Bank).
    12. F J Heather & D Z Childs & A M Darnaude & J L Blanchard, 2018. "Using an integral projection model to assess the effect of temperature on the growth of gilthead seabream Sparus aurata," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-19, May.
    13. Valentina Krenz & Arjen Alink & Tobias Sommer & Benno Roozendaal & Lars Schwabe, 2023. "Time-dependent memory transformation in hippocampus and neocortex is semantic in nature," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    14. Morán-Ordóñez, Alejandra & Ameztegui, Aitor & De Cáceres, Miquel & de-Miguel, Sergio & Lefèvre, François & Brotons, Lluís & Coll, Lluís, 2020. "Future trade-offs and synergies among ecosystem services in Mediterranean forests under global change scenarios," Ecosystem Services, Elsevier, vol. 45(C).
    15. Maire, Florian & Moulines, Eric & Lefebvre, Sidonie, 2017. "Online EM for functional data," Computational Statistics & Data Analysis, Elsevier, vol. 111(C), pages 27-47.
    16. Jack McDonnell & Thomas McKenna & Kathryn A. Yurkonis & Deirdre Hennessy & Rafael Andrade Moral & Caroline Brophy, 2023. "A Mixed Model for Assessing the Effect of Numerous Plant Species Interactions on Grassland Biodiversity and Ecosystem Function Relationships," Journal of Agricultural, Biological and Environmental Statistics, Springer;The International Biometric Society;American Statistical Association, vol. 28(1), pages 1-19, March.
    17. Zhang, Danjie & Chen, Ming-Hui & Ibrahim, Joseph G. & Boye, Mark E. & Shen, Wei, 2016. "JMFit: A SAS Macro for Joint Models of Longitudinal and Survival Data," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 71(i03).
    18. Ana Pinto & Tong Yin & Marion Reichenbach & Raghavendra Bhatta & Pradeep Kumar Malik & Eva Schlecht & Sven König, 2020. "Enteric Methane Emissions of Dairy Cattle Considering Breed Composition, Pasture Management, Housing Conditions and Feeding Characteristics along a Rural-Urban Gradient in a Rising Megacity," Agriculture, MDPI, vol. 10(12), pages 1-18, December.
    19. Damian M. Herz & Manuel Bange & Gabriel Gonzalez-Escamilla & Miriam Auer & Keyoumars Ashkan & Petra Fischer & Huiling Tan & Rafal Bogacz & Muthuraman Muthuraman & Sergiu Groppa & Peter Brown, 2022. "Dynamic control of decision and movement speed in the human basal ganglia," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    20. Kathrin Stenchly & Marc Victor Hansen & Katharina Stein & Andreas Buerkert & Wilhelm Loewenstein, 2018. "Income Vulnerability of West African Farming Households to Losses in Pollination Services: A Case Study from Ouagadougou, Burkina Faso," Sustainability, MDPI, vol. 10(11), pages 1-12, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:170:y:2022:i:c:s0167947322000184. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.