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Genetic Predictors of Cognitive Decline and Labor Market Exit

Author

Listed:
  • Borgbjerg, Anne Katrine

    (Aarhus University)

  • Agerbo, Esben

    (Aarhus University)

  • Datta Gupta, Nabanita

    (Aarhus University)

  • Halliday, Timothy J.

    (University of Hawaii at Manoa)

Abstract

We analyze administrative and genetic data from over 200,000 Danes to study the effects of genetic risk for Alzheimer's Disease (AD) on labor market outcomes. Higher AD genetic risk increases dementia diagnoses and GP visits for both genders. Among women aged 45–65, it reduces labor participation and raises disability pension uptake, especially near retirement. These effects weaken for women with high polygenic scores for education. For men, AD genetic risk shows no employment impact. These gender differences align with evidence that AD genetic markers are more predictive in women.

Suggested Citation

  • Borgbjerg, Anne Katrine & Agerbo, Esben & Datta Gupta, Nabanita & Halliday, Timothy J., 2025. "Genetic Predictors of Cognitive Decline and Labor Market Exit," IZA Discussion Papers 17714, Institute of Labor Economics (IZA).
    • Handle: RePEc:iza:izadps:dp17714
    as

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    References listed on IDEAS

    as
    1. Laura Spinney, 2014. "Alzheimer's disease: The forgetting gene," Nature, Nature, vol. 510(7503), pages 26-28, June.
    2. Michael Grossman, 1972. "The Demand for Health: A Theoretical and Empirical Investigation," NBER Books, National Bureau of Economic Research, Inc, number gros72-1, June.
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    More about this item

    Keywords

    Alzheimer's Disease; labor supply; genoeconomics;
    All these keywords.

    JEL classification:

    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • J14 - Labor and Demographic Economics - - Demographic Economics - - - Economics of the Elderly; Economics of the Handicapped; Non-Labor Market Discrimination
    • J22 - Labor and Demographic Economics - - Demand and Supply of Labor - - - Time Allocation and Labor Supply

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