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Exploring Differences in Intraoperative Medication Use Between African American and Non-Hispanic White Patients During General Anesthesia: Retrospective Observational Cohort Study

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  • Hideyo Tsumura
  • Wei Pan
  • Debra Brandon

Abstract

This study aimed to explore whether differences exist in anesthesia care providers’ use of intraoperative medication between African American and non-Hispanic White patients in adult surgical patients who underwent noncardiothoracic nonobstetric surgeries with general anesthesia. A retrospective observational cohort study used electronic health records between January 1, 2018 and August 31, 2019 at a large academic health system in the southeastern United States. To evaluate the isolated impact of race on intraoperative medication use, inverse probability of treatment weighting using the propensity scores was used to balance the covariates between African American and non-Hispanic White patients. Regression analyses were then performed to evaluate the impact of race on the total dose of opioid analgesia administered, and the use of midazolam, sugammadex, antihypotensive drugs, and antihypertensive drugs. Of the 31,790 patients included in the sample, 58.9% were non-Hispanic Whites and 13.6% were African American patients. After adjusting for significant covariates, African American patients were more likely to receive midazolam premedication ( p  

Suggested Citation

  • Hideyo Tsumura & Wei Pan & Debra Brandon, 2024. "Exploring Differences in Intraoperative Medication Use Between African American and Non-Hispanic White Patients During General Anesthesia: Retrospective Observational Cohort Study," Clinical Nursing Research, , vol. 33(6), pages 470-480, July.
    • Handle: RePEc:sae:clnure:v:33:y:2024:i:6:p:470-480
    DOI: 10.1177/10547738241253652
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