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Computer-based cognitive interventions in acquired brain injury: A systematic review and meta-analysis of randomized controlled trials

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  • Rodrigo Fernández López
  • Adoración Antolí

Abstract

Introduction: Acquired brain injury (ABI) leads to cognitive deficits in a great variety of cognitive functions. Interventions aimed at reducing such deficits include the use of computer-based cognitive interventions. The present work synthetizes and quantitively analyses the effect of computer-based cognitive interventions in ABI. Methods: PubMed, Scopus, Web of Science, ProQuest and Ovid databases were searched for randomized controlled trials (RCT) addressing this issue. A total number of 8 randomized-controlled trials were included for systematic review and meta-analysis. Univariate meta-analyses were conducted for every cognitive function, producing aggregates when a study contributed more than one effect size per cognitive domain. Results: Random-effects meta-analyses showed an improvement of Visual and Verbal working memory, while other domains like Attention, Processing speed, Executive functions and Memory were not benefited by the interventions. Conclusions: Computer-based cognitive interventions might be a beneficial intervention for ABI population to improve Visual and Verbal working memory, although no effect was found in other cognitive domains. Implications and possible future directions of the research are discussed.

Suggested Citation

  • Rodrigo Fernández López & Adoración Antolí, 2020. "Computer-based cognitive interventions in acquired brain injury: A systematic review and meta-analysis of randomized controlled trials," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-14, July.
  • Handle: RePEc:plo:pone00:0235510
    DOI: 10.1371/journal.pone.0235510
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    References listed on IDEAS

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    1. Amit Lampit & Harry Hallock & Michael Valenzuela, 2014. "Computerized Cognitive Training in Cognitively Healthy Older Adults: A Systematic Review and Meta-Analysis of Effect Modifiers," PLOS Medicine, Public Library of Science, vol. 11(11), pages 1-18, November.
    2. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    3. Megan Spencer-Smith & Torkel Klingberg, 2015. "Benefits of a Working Memory Training Program for Inattention in Daily Life: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-18, March.
    4. Viechtbauer, Wolfgang, 2010. "Conducting Meta-Analyses in R with the metafor Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 36(i03).
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