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Association of functional and structural social support with medication adherence among individuals treated for coronary heart disease risk factors: Findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study

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  • Favel L Mondesir
  • April P Carson
  • Raegan W Durant
  • Marquita W Lewis
  • Monika M Safford
  • Emily B Levitan

Abstract

Background: Functional social support has a stronger association with medical treatment adherence than structural social support in several populations and disease conditions. Using a contemporary U.S. population of adults treated with medications for coronary heart disease (CHD) risk factors, the association between social support and medication adherence was examined. Methods: We included 17,113 black and white men and women with CHD or CHD risk factors aged ≥45 years recruited 2003–2007 from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. Participants reported their perceived social support (structural social support: being partnered, number of close friends, number of close relatives, and number of other adults in household; functional social support: having a caregiver in case of sickness or disability; combination of structural and functional social support: number of close friends or relatives seen at least monthly). Medication adherence was assessed using a 4-item scale. Multi-variable adjusted Poisson regression models were used to calculate prevalence ratios (PR) for the association between social support and medication adherence. Results: Prevalence of medication adherence was 68.9%. Participants who saw >10 close friends or relatives at least monthly had higher prevalence of medication adherence (PR = 1.06; 95% CI: 1.00, 1.11) than those who saw ≤3 per month. Having a caregiver in case of sickness or disability, being partnered, number of close friends, number of close relatives, and number of other adults in household were not associated with medication adherence after adjusting for covariates. Conclusions: Seeing multiple friends and relatives was associated with better medication adherence among individuals with CHD risk factors. Increasing social support with combined structural and functional components may help support medication adherence.

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  • Favel L Mondesir & April P Carson & Raegan W Durant & Marquita W Lewis & Monika M Safford & Emily B Levitan, 2018. "Association of functional and structural social support with medication adherence among individuals treated for coronary heart disease risk factors: Findings from the REasons for Geographic and Racial," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-13, June.
    • Handle: RePEc:plo:pone00:0198578
    DOI: 10.1371/journal.pone.0198578
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    References listed on IDEAS

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    1. Favel L. Mondesir & Kellee White & Angela D. Liese & Alexander C. McLain, 2016. "Gender, Illness-Related Diabetes Social Support, and Glycemic Control Among Middle-Aged and Older Adults," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 71(6), pages 1081-1088.
    2. Royston, Patrick & White, Ian R., 2011. "Multiple Imputation by Chained Equations (MICE): Implementation in Stata," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 45(i04).
    3. Williams, Holly Ann, 1993. "A comparison of social support and social networks of black parents and white parents with chronically ill children," Social Science & Medicine, Elsevier, vol. 37(12), pages 1509-1520, December.
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    1. Amanual Getnet Mersha & Michelle Kennedy & Parivash Eftekhari & Gillian Sandra Gould, 2021. "Predictors of Adherence to Smoking Cessation Medications among Current and Ex-Smokers in Australia: Findings from a National Cross-Sectional Survey," IJERPH, MDPI, vol. 18(22), pages 1-14, November.
    2. Cristina M Lozano-Hernández & Juan A López-Rodríguez & Francisca Leiva-Fernández & Amaia Calderón-Larrañaga & Jaime Barrio-Cortes & Luis A Gimeno-Feliu & Beatriz Poblador-Plou & Isabel del Cura-Gonzál, 2020. "Social support, social context and nonadherence to treatment in young senior patients with multimorbidity and polypharmacy followed-up in primary care. MULTIPAP Study," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-15, June.

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