Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-024-53451-7
Download full text from publisher
References listed on IDEAS
- Robert Vander Velde & Nara Yoon & Viktoriya Marusyk & Arda Durmaz & Andrew Dhawan & Daria Miroshnychenko & Diego Lozano-Peral & Bina Desai & Olena Balynska & Jan Poleszhuk & Liu Kenian & Mingxiang Ten, 2020. "Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Anna C. Obenauf & Yilong Zou & Andrew L. Ji & Sakari Vanharanta & Weiping Shu & Hubing Shi & Xiangju Kong & Marcus C. Bosenberg & Thomas Wiesner & Neal Rosen & Roger S. Lo & Joan Massagué, 2015. "Therapy-induced tumour secretomes promote resistance and tumour progression," Nature, Nature, vol. 520(7547), pages 368-372, April.
- Ravid Straussman & Teppei Morikawa & Kevin Shee & Michal Barzily-Rokni & Zhi Rong Qian & Jinyan Du & Ashli Davis & Margaret M. Mongare & Joshua Gould & Dennie T. Frederick & Zachary A. Cooper & Paul B, 2012. "Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion," Nature, Nature, vol. 487(7408), pages 500-504, July.
- Timothy R. Wilson & Jane Fridlyand & Yibing Yan & Elicia Penuel & Luciana Burton & Emily Chan & Jing Peng & Eva Lin & Yulei Wang & Jeff Sosman & Antoni Ribas & Jiang Li & John Moffat & Daniel P. Suthe, 2012. "Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors," Nature, Nature, vol. 487(7408), pages 505-509, July.
- Anirudh Prahallad & Chong Sun & Sidong Huang & Federica Di Nicolantonio & Ramon Salazar & Davide Zecchin & Roderick L. Beijersbergen & Alberto Bardelli & René Bernards, 2012. "Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR," Nature, Nature, vol. 483(7387), pages 100-103, March.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Daniel E Carlin & Barry Demchak & Dexter Pratt & Eric Sage & Trey Ideker, 2017. "Network propagation in the cytoscape cyberinfrastructure," PLOS Computational Biology, Public Library of Science, vol. 13(10), pages 1-9, October.
- Jiaxin Liang & Deyang Yu & Chi Luo & Christopher Bennett & Mark Jedrychowski & Steve P. Gygi & Hans R. Widlund & Pere Puigserver, 2023. "Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
- Ke Gong & Gao Guo & Nicole A. Beckley & Xiaoyao Yang & Yue Zhang & David E. Gerber & John D. Minna & Sandeep Burma & Dawen Zhao & Esra A. Akbay & Amyn A. Habib, 2021. "Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
- Mathurin Dorel & Bertram Klinger & Tommaso Mari & Joern Toedling & Eric Blanc & Clemens Messerschmidt & Michal Nadler-Holly & Matthias Ziehm & Anja Sieber & Falk Hertwig & Dieter Beule & Angelika Egge, 2021. "Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance," PLOS Computational Biology, Public Library of Science, vol. 17(11), pages 1-26, November.
- Jin Jin & Qianying Liu & Wei Zheng & Zhenming Shun & Tun Tun Lin & Lei Gao & Yingwen Dong, 2020. "A Bayesian Method for the Detection of Proof of Concept in Early Phase Oncology Studies with a Basket Design," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 12(2), pages 167-179, July.
- Gholamreza Safaee Ardekani & Seyed Mehdi Jafarnejad & Larry Tan & Ardavan Saeedi & Gang Li, 2012. "The Prognostic Value of BRAF Mutation in Colorectal Cancer and Melanoma: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-10, October.
- Francesca Menghi & Edison T. Liu, 2022. "Functional genomics of complex cancer genomes," Nature Communications, Nature, vol. 13(1), pages 1-4, December.
- Josefine Radke & Elisa Schumann & Julia Onken & Randi Koll & Güliz Acker & Bohdan Bodnar & Carolin Senger & Sascha Tierling & Markus Möbs & Peter Vajkoczy & Anna Vidal & Sandra Högler & Petra Kodajova, 2022. "Decoding molecular programs in melanoma brain metastases," Nature Communications, Nature, vol. 13(1), pages 1-24, December.
- Victoria O. Shender & Ksenia S. Anufrieva & Polina V. Shnaider & Georgij P. Arapidi & Marat S. Pavlyukov & Olga M. Ivanova & Irina K. Malyants & Grigory A. Stepanov & Evgenii Zhuravlev & Rustam H. Zig, 2024. "Therapy-induced secretion of spliceosomal components mediates pro-survival crosstalk between ovarian cancer cells," Nature Communications, Nature, vol. 15(1), pages 1-26, December.
- Ryan T. Bishop & Anna K. Miller & Matthew Froid & Niveditha Nerlakanti & Tao Li & Jeremy S. Frieling & Mostafa M. Nasr & Karl J. Nyman & Praneeth R. Sudalagunta & Rafael R. Canevarolo & Ariosto Siquei, 2024. "The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Karin Schmelz & Joern Toedling & Matt Huska & Maja C. Cwikla & Louisa-Marie Kruetzfeldt & Jutta Proba & Peter F. Ambros & Inge M. Ambros & Sengül Boral & Marco Lodrini & Celine Y. Chen & Martin Burker, 2021. "Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
- Naomi Kawashima & Yuichi Ishikawa & Jeong Hui Kim & Yoko Ushijima & Akimi Akashi & Yohei Yamaguchi & Hikaru Hattori & Marie Nakashima & Seara Ikeno & Rika Kihara & Takahiro Nishiyama & Takanobu Morish, 2022. "Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-53451-7. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.