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Genomic evidence of two-staged transmission of the early seventh cholera pandemic

Author

Listed:
  • Yun Luo

    (University of New South Wales)

  • Michael Payne

    (University of New South Wales)

  • Sandeep Kaur

    (University of New South Wales)

  • Sophie Octavia

    (University of New South Wales)

  • Ruiting Lan

    (University of New South Wales)

Abstract

The seventh cholera pandemic started in 1961 in Indonesia and spread across the world in three waves in the decades that followed. Here, we utilised genomic evidence to detail the first wave of the seventh pandemic. Genomes of 22 seventh pandemic Vibrio cholerae isolates from 1961 to 1979 were completely sequenced. Together with 152 publicly available genomes from the same period, they fell into seven phylogenetic clusters (CL1–CL7). By multilevel genome typing (MGT), all were assigned to MGT2 ST1 (Wave 1) except three isolates in CL7 which were typed as MGT2 ST2 (Wave 2). The Wave 1 seventh pandemic expanded in two stages, with Stage 1 (CL1–CL5) spread across Asia and Stage 2 (CL6 and CL7) spread to the Middle East and Africa. Three non-synonymous mutations, one each, in three regulatory genes, csrD (global regulator), acfB (chemotaxis), and luxO (quorum sensing) may have critically contributed to its pandemicity. The three MGT2 ST2 isolates in CL7 were the progenitors of Wave 2 and evolved from within Wave 1 with acquisition of a novel IncA/C plasmid. Our findings provide new insight into the evolution and transmission of the early seventh pandemic, which may aid future cholera prevention and control.

Suggested Citation

  • Yun Luo & Michael Payne & Sandeep Kaur & Sophie Octavia & Ruiting Lan, 2024. "Genomic evidence of two-staged transmission of the early seventh cholera pandemic," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52800-w
    DOI: 10.1038/s41467-024-52800-w
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    1. François-Xavier Weill & Daryl Domman & Elisabeth Njamkepo & Abdullrahman A. Almesbahi & Mona Naji & Samar Saeed Nasher & Ankur Rakesh & Abdullah M. Assiri & Naresh Chand Sharma & Samuel Kariuki & Moha, 2019. "Genomic insights into the 2016–2017 cholera epidemic in Yemen," Nature, Nature, vol. 565(7738), pages 230-233, January.
    2. Ankur Mutreja & Dong Wook Kim & Nicholas R. Thomson & Thomas R. Connor & Je Hee Lee & Samuel Kariuki & Nicholas J. Croucher & Seon Young Choi & Simon R. Harris & Michael Lebens & Swapan Kumar Niyogi &, 2011. "Evidence for several waves of global transmission in the seventh cholera pandemic," Nature, Nature, vol. 477(7365), pages 462-465, September.
    3. Md Mamun Monir & Mohammad Tarequl Islam & Razib Mazumder & Dinesh Mondal & Kazi Sumaita Nahar & Marzia Sultana & Masatomo Morita & Makoto Ohnishi & Anwar Huq & Haruo Watanabe & Firdausi Qadri & Mustaf, 2023. "Genomic attributes of Vibrio cholerae O1 responsible for 2022 massive cholera outbreak in Bangladesh," Nature Communications, Nature, vol. 14(1), pages 1-8, December.
    4. Mihaela Oprea & Elisabeth Njamkepo & Daniela Cristea & Anna Zhukova & Clifford G. Clark & Anatoly N. Kravetz & Elena Monakhova & Adriana S. Ciontea & Radu Cojocaru & Jean Rauzier & Maria Damian & Oliv, 2020. "The seventh pandemic of cholera in Europe revisited by microbial genomics," Nature Communications, Nature, vol. 11(1), pages 1-10, December.
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