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A bioabsorbable mechanoelectric fiber as electrical stimulation suture

Author

Listed:
  • Zhouquan Sun

    (Donghua University)

  • Yuefan Jin

    (Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)

  • Jiabei Luo

    (Donghua University)

  • Linpeng Li

    (Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)

  • Yue Ding

    (Tongji University Medical School)

  • Yu Luo

    (School of Chemistry and Chemical Engineering Shanghai University of Engineering Science)

  • Yan Qi

    (Tongji University School of Medicine)

  • Yaogang Li

    (Donghua University)

  • Qinghong Zhang

    (Donghua University)

  • Kerui Li

    (Donghua University)

  • Haibo Shi

    (Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)

  • Shankai Yin

    (Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)

  • Hongzhi Wang

    (Donghua University)

  • Hui Wang

    (Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine)

  • Chengyi Hou

    (Donghua University)

Abstract

In surgical medicine, suturing is the standard treatment for large incisions, yet traditional sutures are limited in functionality. Electrical stimulation is a non-pharmacological therapy that promotes wound healing. In this context, we designed a passive and biodegradable mechanoelectric suture. The suture consists of multi-layer coaxial structure composed of (poly(lactic-co-glycolic acid), polycaprolactone) and magnesium to allow safe degradation. In addition to the excellent mechanical properties, the mechanoelectrical nature of the suture grants the generation of electric fields in response to movement and stretching. This is shown to speed up wound healing by 50% and reduce the risk of infection. This work presents an evolution of the conventional wound closure procedures, using a safe and degradable device ready to be translated into clinical practice.

Suggested Citation

  • Zhouquan Sun & Yuefan Jin & Jiabei Luo & Linpeng Li & Yue Ding & Yu Luo & Yan Qi & Yaogang Li & Qinghong Zhang & Kerui Li & Haibo Shi & Shankai Yin & Hongzhi Wang & Hui Wang & Chengyi Hou, 2024. "A bioabsorbable mechanoelectric fiber as electrical stimulation suture," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52354-x
    DOI: 10.1038/s41467-024-52354-x
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    References listed on IDEAS

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