IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v15y2024i1d10.1038_s41467-024-52186-9.html
   My bibliography  Save this article

The morphospace of the brain-cognition organisation

Author

Listed:
  • Valentina Pacella

    (Scuola Universitaria Superiore IUSS
    University of Bordeaux
    Brain Connectivity and Behaviour Laboratory)

  • Victor Nozais

    (University of Bordeaux
    Brain Connectivity and Behaviour Laboratory)

  • Lia Talozzi

    (University of Bordeaux
    Brain Connectivity and Behaviour Laboratory
    Stanford)

  • Majd Abdallah

    (University of Bordeaux
    Brain Connectivity and Behaviour Laboratory
    1 Rue Honoré d’Estienne d’Orves
    Gif-sur-Yvette)

  • Demian Wassermann

    (1 Rue Honoré d’Estienne d’Orves
    Gif-sur-Yvette)

  • Stephanie J. Forkel

    (Brain Connectivity and Behaviour Laboratory
    Thomas van Aquinostraat 4
    King’s College London
    Max Planck Institute for Psycholinguistics)

  • Michel Thiebaut de Schotten

    (University of Bordeaux
    Brain Connectivity and Behaviour Laboratory)

Abstract

Over the past three decades, functional neuroimaging has amassed abundant evidence of the intricate interplay between brain structure and function. However, the potential anatomical and experimental overlap, independence, granularity, and gaps between functions remain poorly understood. Here, we show the latent structure of the current brain-cognition knowledge and its organisation. Our approach utilises the most comprehensive meta-analytic fMRI database (Neurosynth) to compute a three-dimensional embedding space–morphospace capturing the relationship between brain functions as we currently understand them. The space structure enables us to statistically test the relationship between functions expressed as the degree to which the characteristics of each functional map can be anticipated based on its similarities with others–the predictability index. The morphospace can also predict the activation pattern of new, unseen functions and decode thoughts and inner states during movie watching. The framework defined by the morphospace will spur the investigation of novel functions and guide the exploration of the fabric of human cognition.

Suggested Citation

  • Valentina Pacella & Victor Nozais & Lia Talozzi & Majd Abdallah & Demian Wassermann & Stephanie J. Forkel & Michel Thiebaut de Schotten, 2024. "The morphospace of the brain-cognition organisation," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52186-9
    DOI: 10.1038/s41467-024-52186-9
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-024-52186-9
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-024-52186-9?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Janet M. Box-Steffensmeier & Jean Burgess & Maurizio Corbetta & Kate Crawford & Esther Duflo & Laurel Fogarty & Alison Gopnik & Sari Hanafi & Mario Herrero & Ying-yi Hong & Yasuko Kameyama & Tatia M. , 2022. "The future of human behaviour research," Nature Human Behaviour, Nature, vol. 6(1), pages 15-24, January.
    2. Scott Marek & Brenden Tervo-Clemmens & Finnegan J. Calabro & David F. Montez & Benjamin P. Kay & Alexander S. Hatoum & Meghan Rose Donohue & William Foran & Ryland L. Miller & Timothy J. Hendrickson &, 2022. "Reproducible brain-wide association studies require thousands of individuals," Nature, Nature, vol. 603(7902), pages 654-660, March.
    3. Vyacheslav R. Karolis & Maurizio Corbetta & Michel Thiebaut de Schotten, 2019. "The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain," Nature Communications, Nature, vol. 10(1), pages 1-9, December.
    4. Mishkin, Frederic S., 1981. "The real interest rate: An empirical investigation," Carnegie-Rochester Conference Series on Public Policy, Elsevier, vol. 15(1), pages 151-200, January.
    5. Jonathan D. Cohen & William M. Perlstein & Todd S. Braver & Leigh E. Nystrom & Douglas C. Noll & John Jonides & Edward E. Smith, 1997. "Temporal dynamics of brain activation during a working memory task," Nature, Nature, vol. 386(6625), pages 604-608, April.
    6. Kartik K. Iyer & Kai Hwang & Luke J. Hearne & Eli Muller & Mark D’Esposito & James M. Shine & Luca Cocchi, 2022. "Focal neural perturbations reshape low-dimensional trajectories of brain activity supporting cognitive performance," Nature Communications, Nature, vol. 13(1), pages 1-8, December.
    7. Matthew F. Glasser & Timothy S. Coalson & Emma C. Robinson & Carl D. Hacker & John Harwell & Essa Yacoub & Kamil Ugurbil & Jesper Andersson & Christian F. Beckmann & Mark Jenkinson & Stephen M. Smith , 2016. "A multi-modal parcellation of human cerebral cortex," Nature, Nature, vol. 536(7615), pages 171-178, August.
    8. Zarnowitz, Victor, 1985. "Rational Expectations and Macroeconomic Forecasts," Journal of Business & Economic Statistics, American Statistical Association, vol. 3(4), pages 293-311, October.
    9. Rodrigo P. Rocha & Loren Koçillari & Samir Suweis & Michele Filippo De Grazia & Michel Thiebaut Schotten & Marco Zorzi & Maurizio Corbetta, 2022. "Recovery of neural dynamics criticality in personalized whole-brain models of stroke," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Dardo Tomasi & Nora D. Volkow, 2024. "Associations between handedness and brain functional connectivity patterns in children," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    2. Crockett, Jean A., 1998. "Rational expectations, inflation and the nominal interest rate," Journal of Econometrics, Elsevier, vol. 83(1-2), pages 349-363.
    3. Golia Shafiei & Ben D. Fulcher & Bradley Voytek & Theodore D. Satterthwaite & Sylvain Baillet & Bratislav Misic, 2023. "Neurophysiological signatures of cortical micro-architecture," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    4. Mohamed Abdelhack & Peter Zhukovsky & Milos Milic & Shreyas Harita & Michael Wainberg & Shreejoy J. Tripathy & John D. Griffiths & Sean L. Hill & Daniel Felsky, 2023. "Opposing brain signatures of sleep in task-based and resting-state conditions," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    5. Andrew D. Grotzinger & Travis T. Mallard & Zhaowen Liu & Jakob Seidlitz & Tian Ge & Jordan W. Smoller, 2023. "Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    6. Meike D. Hettwer & Lena Dorfschmidt & Lara M. C. Puhlmann & Linda M. Jacob & Casey Paquola & Richard A. I. Bethlehem & Edward T. Bullmore & Simon B. Eickhoff & Sofie L. Valk, 2024. "Longitudinal variation in resilient psychosocial functioning is associated with ongoing cortical myelination and functional reorganization during adolescence," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    7. Audrey C. Luo & Valerie J. Sydnor & Adam Pines & Bart Larsen & Aaron F. Alexander-Bloch & Matthew Cieslak & Sydney Covitz & Andrew A. Chen & Nathalia Bianchini Esper & Eric Feczko & Alexandre R. Franc, 2024. "Functional connectivity development along the sensorimotor-association axis enhances the cortical hierarchy," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    8. Benjamin Lahner & Kshitij Dwivedi & Polina Iamshchinina & Monika Graumann & Alex Lascelles & Gemma Roig & Alessandro Thomas Gifford & Bowen Pan & SouYoung Jin & N. Apurva Ratan Murty & Kendrick Kay & , 2024. "Modeling short visual events through the BOLD moments video fMRI dataset and metadata," Nature Communications, Nature, vol. 15(1), pages 1-26, December.
    9. Loïc Labache & Tian Ge & B. T. Thomas Yeo & Avram J. Holmes, 2023. "Language network lateralization is reflected throughout the macroscale functional organization of cortex," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    10. Arielle S. Keller & Adam R. Pines & Sheila Shanmugan & Valerie J. Sydnor & Zaixu Cui & Maxwell A. Bertolero & Ran Barzilay & Aaron F. Alexander-Bloch & Nora Byington & Andrew Chen & Gregory M. Conan &, 2023. "Personalized functional brain network topography is associated with individual differences in youth cognition," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    11. Graham Elliott & Ivana Komunjer & Allan Timmermann, 2008. "Biases in Macroeconomic Forecasts: Irrationality or Asymmetric Loss?," Journal of the European Economic Association, MIT Press, vol. 6(1), pages 122-157, March.
    12. Sirichand, Kavita & Vivian, Andrew & Wohar, Mark E., 2015. "Examining real interest parity: Which component reverts quickest and in which regime?," International Review of Financial Analysis, Elsevier, vol. 39(C), pages 72-83.
    13. Max Korbmacher & Dennis Meer & Dani Beck & Ann-Marie G. de Lange & Eli Eikefjord & Arvid Lundervold & Ole A. Andreassen & Lars T. Westlye & Ivan I. Maximov, 2024. "Brain asymmetries from mid- to late life and hemispheric brain age," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    14. Hakan Berument & Nildag Basak Ceylan & Hasan Olgun, 2007. "Inflation uncertainty and interest rates: is the Fisher relation universal?," Applied Economics, Taylor & Francis Journals, vol. 39(1), pages 53-68.
    15. Bob Bramson & Sjoerd Meijer & Annelies Nuland & Ivan Toni & Karin Roelofs, 2023. "Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
    16. Kanas, Angelos, 2008. "On real interest rate dynamics and regime switching," Journal of Banking & Finance, Elsevier, vol. 32(10), pages 2089-2098, October.
    17. Matthew Rosenblatt & Link Tejavibulya & Rongtao Jiang & Stephanie Noble & Dustin Scheinost, 2024. "Data leakage inflates prediction performance in connectome-based machine learning models," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    18. Alisdair McKay, "undated". "Idiosyncratic risk, insurance, and aggregate consumption dynamics: a likelihood perspective," Boston University - Department of Economics - Working Papers Series 2013-013, Boston University - Department of Economics.
    19. Christina D. Romer & David H. Romer, 1994. "What Ends Recessions?," NBER Chapters, in: NBER Macroeconomics Annual 1994, Volume 9, pages 13-80, National Bureau of Economic Research, Inc.
    20. Thomas Mayer, 1998. "Indexed Bonds And Heterogeneous Agents," Contemporary Economic Policy, Western Economic Association International, vol. 16(1), pages 77-84, January.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52186-9. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.