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Associations between handedness and brain functional connectivity patterns in children

Author

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  • Dardo Tomasi

    (National Institute on Alcohol Abuse and Alcoholism)

  • Nora D. Volkow

    (National Institute on Alcohol Abuse and Alcoholism)

Abstract

Handedness develops early in life, but the structural and functional brain connectivity patterns associated with it remains unknown. Here we investigate associations between handedness and the asymmetry of brain connectivity in 9- to 10-years old children from the Adolescent Brain Cognitive Development (ABCD) study. Compared to right-handers, left-handers had increased global functional connectivity density in the left-hand motor area and decreased it in the right-hand motor area. A connectivity-based index of handedness provided a sharper differentiation between right- and left-handers. The laterality of hand-motor connectivity varied as a function of handedness in unimodal sensorimotor cortices, heteromodal areas, and cerebellum (P

Suggested Citation

  • Dardo Tomasi & Nora D. Volkow, 2024. "Associations between handedness and brain functional connectivity patterns in children," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-46690-1
    DOI: 10.1038/s41467-024-46690-1
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