Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization
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DOI: 10.1038/s41467-024-50548-x
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- Antoine Koehl & Hongli Hu & Dan Feng & Bingfa Sun & Yan Zhang & Michael J. Robertson & Matthew Chu & Tong Sun Kobilka & Toon Laeremans & Jan Steyaert & Jeffrey Tarrasch & Somnath Dutta & Rasmus Fonsec, 2019. "Author Correction: Structural insights into the activation of metabotropic glutamate receptors," Nature, Nature, vol. 567(7747), pages 10-10, March.
- Arun K. Shukla & Gerwin H. Westfield & Kunhong Xiao & Rosana I. Reis & Li-Yin Huang & Prachi Tripathi-Shukla & Jiang Qian & Sheng Li & Adi Blanc & Austin N. Oleskie & Anne M. Dosey & Min Su & Cui-Rong, 2014. "Visualization of arrestin recruitment by a G-protein-coupled receptor," Nature, Nature, vol. 512(7513), pages 218-222, August.
- Antoine Koehl & Hongli Hu & Dan Feng & Bingfa Sun & Yan Zhang & Michael J. Robertson & Matthew Chu & Tong Sun Kobilka & Toon Laeremans & Jan Steyaert & Jeffrey Tarrasch & Somnath Dutta & Rasmus Fonsec, 2019. "Structural insights into the activation of metabotropic glutamate receptors," Nature, Nature, vol. 566(7742), pages 79-84, February.
- Weijiao Huang & Matthieu Masureel & Qianhui Qu & John Janetzko & Asuka Inoue & Hideaki E. Kato & Michael J. Robertson & Khanh C. Nguyen & Jeffrey S. Glenn & Georgios Skiniotis & Brian K. Kobilka, 2020. "Structure of the neurotensin receptor 1 in complex with β-arrestin 1," Nature, Nature, vol. 579(7798), pages 303-308, March.
- Hamidreza Shaye & Andrii Ishchenko & Jordy Homing Lam & Gye Won Han & Li Xue & Philippe Rondard & Jean-Philippe Pin & Vsevolod Katritch & Cornelius Gati & Vadim Cherezov, 2020. "Structural basis of the activation of a metabotropic GABA receptor," Nature, Nature, vol. 584(7820), pages 298-303, August.
- Linnea Olofsson & Suren Felekyan & Etienne Doumazane & Pauline Scholler & Ludovic Fabre & Jurriaan M. Zwier & Philippe Rondard & Claus A. M. Seidel & Jean-Philippe Pin & Emmanuel Margeat, 2014. "Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy," Nature Communications, Nature, vol. 5(1), pages 1-12, December.
- Chris H. Habrian & Joshua Levitz & Vojtech Vyklicky & Zhu Fu & Adam Hoagland & Isabelle McCort-Tranchepain & Francine Acher & Ehud Y. Isacoff, 2019. "Conformational pathway provides unique sensitivity to a synaptic mGluR," Nature Communications, Nature, vol. 10(1), pages 1-13, December.
- Alpay B. Seven & Ximena Barros-Álvarez & Marine Lapeyrière & Makaía M. Papasergi-Scott & Michael J. Robertson & Chensong Zhang & Robert M. Nwokonko & Yang Gao & Justin G. Meyerowitz & Jean-Philippe Ro, 2021. "G-protein activation by a metabotropic glutamate receptor," Nature, Nature, vol. 595(7867), pages 450-454, July.
- Yang Gao & Michael J. Robertson & Sabrina N. Rahman & Alpay B. Seven & Chensong Zhang & Justin G. Meyerowitz & Ouliana Panova & Fadil M. Hannan & Rajesh V. Thakker & Hans Bräuner-Osborne & Jesper M. M, 2021. "Asymmetric activation of the calcium-sensing receptor homodimer," Nature, Nature, vol. 595(7867), pages 455-459, July.
- Jinseo Park & Ziao Fu & Aurel Frangaj & Jonathan Liu & Lidia Mosyak & Tong Shen & Vesna N. Slavkovich & Kimberly M. Ray & Jaume Taura & Baohua Cao & Yong Geng & Hao Zuo & Yongjun Kou & Robert Grassucc, 2020. "Structure of human GABAB receptor in an inactive state," Nature, Nature, vol. 584(7820), pages 304-309, August.
- Makaía M. Papasergi-Scott & Michael J. Robertson & Alpay B. Seven & Ouliana Panova & Jesper M. Mathiesen & Georgios Skiniotis, 2020. "Structures of metabotropic GABAB receptor," Nature, Nature, vol. 584(7820), pages 310-314, August.
- Reza Vafabakhsh & Joshua Levitz & Ehud Y. Isacoff, 2015. "Conformational dynamics of a class C G-protein-coupled receptor," Nature, Nature, vol. 524(7566), pages 497-501, August.
- Juan Du & Dejian Wang & Hongcheng Fan & Chanjuan Xu & Linhua Tai & Shuling Lin & Shuo Han & Qiuxiang Tan & Xinwei Wang & Tuo Xu & Hui Zhang & Xiaojing Chu & Cuiying Yi & Peng Liu & Xiaomei Wang & Yu Z, 2021. "Structures of human mGlu2 and mGlu7 homo- and heterodimers," Nature, Nature, vol. 594(7864), pages 589-593, June.
- Jinseo Park & Ziao Fu & Aurel Frangaj & Jonathan Liu & Lidia Mosyak & Tong Shen & Vesna N. Slavkovich & Kimberly M. Ray & Jaume Taura & Baohua Cao & Yong Geng & Hao Zuo & Yongjun Kou & Robert Grassucc, 2020. "Author Correction: Structure of human GABAB receptor in an inactive state," Nature, Nature, vol. 583(7818), pages 29-29, July.
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