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Neural representational geometries reflect behavioral differences in monkeys and recurrent neural networks

Author

Listed:
  • Valeria Fascianelli

    (Columbia University
    Columbia University)

  • Aldo Battista

    (New York University)

  • Fabio Stefanini

    (Columbia University
    Columbia University)

  • Satoshi Tsujimoto

    (SixthFactor Pte. Ltd)

  • Aldo Genovesio

    (Sapienza University of Rome)

  • Stefano Fusi

    (Columbia University
    Columbia University
    Columbia University Irving Medical Center
    Columbia University)

Abstract

Animals likely use a variety of strategies to solve laboratory tasks. Traditionally, combined analysis of behavioral and neural recording data across subjects employing different strategies may obscure important signals and give confusing results. Hence, it is essential to develop techniques that can infer strategy at the single-subject level. We analyzed an experiment in which two male monkeys performed a visually cued rule-based task. The analysis of their performance shows no indication that they used a different strategy. However, when we examined the geometry of stimulus representations in the state space of the neural activities recorded in dorsolateral prefrontal cortex, we found striking differences between the two monkeys. Our purely neural results induced us to reanalyze the behavior. The new analysis showed that the differences in representational geometry are associated with differences in the reaction times, revealing behavioral differences we were unaware of. All these analyses suggest that the monkeys are using different strategies. Finally, using recurrent neural network models trained to perform the same task, we show that these strategies correlate with the amount of training, suggesting a possible explanation for the observed neural and behavioral differences.

Suggested Citation

  • Valeria Fascianelli & Aldo Battista & Fabio Stefanini & Satoshi Tsujimoto & Aldo Genovesio & Stefano Fusi, 2024. "Neural representational geometries reflect behavioral differences in monkeys and recurrent neural networks," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-50503-w
    DOI: 10.1038/s41467-024-50503-w
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    References listed on IDEAS

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