mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism
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DOI: 10.1038/s41467-024-48386-y
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- Ilaria Elia & Dorien Broekaert & Stefan Christen & Ruben Boon & Enrico Radaelli & Martin F. Orth & Catherine Verfaillie & Thomas G. P. Grünewald & Sarah-Maria Fendt, 2017. "Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells," Nature Communications, Nature, vol. 8(1), pages 1-11, August.
- Andrew C. Hsieh & Yi Liu & Merritt P. Edlind & Nicholas T. Ingolia & Matthew R. Janes & Annie Sher & Evan Y. Shi & Craig R. Stumpf & Carly Christensen & Michael J. Bonham & Shunyou Wang & Pingda Ren &, 2012. "The translational landscape of mTOR signalling steers cancer initiation and metastasis," Nature, Nature, vol. 485(7396), pages 55-61, May.
- Zachary T. Schafer & Alexandra R. Grassian & Loling Song & Zhenyang Jiang & Zachary Gerhart-Hines & Hanna Y. Irie & Sizhen Gao & Pere Puigserver & Joan S. Brugge, 2009. "Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment," Nature, Nature, vol. 461(7260), pages 109-113, September.
- Carson C. Thoreen & Lynne Chantranupong & Heather R. Keys & Tim Wang & Nathanael S. Gray & David M. Sabatini, 2012. "A unifying model for mTORC1-mediated regulation of mRNA translation," Nature, Nature, vol. 485(7396), pages 109-113, May.
- Sang-Min Jeon & Navdeep S. Chandel & Nissim Hay, 2012. "AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress," Nature, Nature, vol. 485(7400), pages 661-665, May.
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