IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v485y2012i7400d10.1038_nature11066.html
   My bibliography  Save this article

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

Author

Listed:
  • Sang-Min Jeon

    (College of Medicine, University of Illinois at Chicago
    Present address: Research Oncology, Genentech, South San Francisco, California 94080, USA)

  • Navdeep S. Chandel

    (Northwestern University Medical School)

  • Nissim Hay

    (College of Medicine, University of Illinois at Chicago)

Abstract

A mechanism is suggested that helps tumour cells survive energy stress conditions during early stages of tumorigenesis.

Suggested Citation

  • Sang-Min Jeon & Navdeep S. Chandel & Nissim Hay, 2012. "AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress," Nature, Nature, vol. 485(7400), pages 661-665, May.
    • Handle: RePEc:nat:nature:v:485:y:2012:i:7400:d:10.1038_nature11066
    DOI: 10.1038/nature11066
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature11066
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature11066?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Rongli Sun & Meng Cao & Juan Zhang & Wenwen Yang & Haiyan Wei & Xing Meng & Lihong Yin & Yuepu Pu, 2016. "Benzene Exposure Alters Expression of Enzymes Involved in Fatty Acid β-Oxidation in Male C3H/He Mice," IJERPH, MDPI, vol. 13(11), pages 1-11, October.
    2. Ipshita Nandi & Linjia Ji & Harvey W. Smith & Daina Avizonis & Vasilios Papavasiliou & Cynthia Lavoie & Alain Pacis & Sherif Attalla & Virginie Sanguin-Gendreau & William J. Muller, 2024. "Targeting fatty acid oxidation enhances response to HER2-targeted therapy," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    3. Ji-Man Park & Da-Hye Lee & Do-Hyung Kim, 2023. "Redefining the role of AMPK in autophagy and the energy stress response," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    4. Jayaraman, K. & Paramasivan, Lavinsaa & Kiumarsi, Shaian, 2017. "Reasons for low penetration on the purchase of photovoltaic (PV) panel system among Malaysian landed property owners," Renewable and Sustainable Energy Reviews, Elsevier, vol. 80(C), pages 562-571.
    5. Tal Levy & Kai Voeltzke & Laura Hruby & Khawla Alasad & Zuelal Bas & Marteinn Snaebjörnsson & Ran Marciano & Katerina Scharov & Mélanie Planque & Kim Vriens & Stefan Christen & Cornelius M. Funk & Chr, 2024. "mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    6. Héctor García Martín & Vinay Satish Kumar & Daniel Weaver & Amit Ghosh & Victor Chubukov & Aindrila Mukhopadhyay & Adam Arkin & Jay D Keasling, 2015. "A Method to Constrain Genome-Scale Models with 13C Labeling Data," PLOS Computational Biology, Public Library of Science, vol. 11(9), pages 1-34, September.
    7. Wei Liu & Hongchao Cao & Jing Wang & Areeg Elmusrati & Bing Han & Wei Chen & Ping Zhou & Xiyao Li & Stephen Keysar & Antonio Jimeno & Cun-Yu Wang, 2024. "Histone-methyltransferase KMT2D deficiency impairs the Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous cell carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-18, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:485:y:2012:i:7400:d:10.1038_nature11066. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.