AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-024-44772-8
Download full text from publisher
References listed on IDEAS
- Jaekyoung Son & Costas A. Lyssiotis & Haoqiang Ying & Xiaoxu Wang & Sujun Hua & Matteo Ligorio & Rushika M. Perera & Cristina R. Ferrone & Edouard Mullarky & Ng Shyh-Chang & Ya’an Kang & Jason B. Flem, 2013. "Correction: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway," Nature, Nature, vol. 499(7459), pages 504-504, July.
- Peng Jiang & Wenjing Du & Anthony Mancuso & Kathryn E. Wellen & Xiaolu Yang, 2013. "Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence," Nature, Nature, vol. 493(7434), pages 689-693, January.
- Jaekyoung Son & Costas A. Lyssiotis & Haoqiang Ying & Xiaoxu Wang & Sujun Hua & Matteo Ligorio & Rushika M. Perera & Cristina R. Ferrone & Edouard Mullarky & Ng Shyh-Chang & Ya’an Kang & Jason B. Flem, 2013. "Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway," Nature, Nature, vol. 496(7443), pages 101-105, April.
- Prasenjit Dey & Joelle Baddour & Florian Muller & Chia Chin Wu & Huamin Wang & Wen-Ting Liao & Zangdao Lan & Alina Chen & Tony Gutschner & Yaan Kang & Jason Fleming & Nikunj Satani & Di Zhao & Abhinav, 2017. "Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer," Nature, Nature, vol. 542(7639), pages 119-123, February.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- C. Megan Young & Laurent Beziaud & Pierre Dessen & Angela Madurga Alonso & Albert Santamaria-Martínez & Joerg Huelsken, 2023. "Metabolic dependencies of metastasis-initiating cells in female breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Kimberley McGrail & Paula Granado-Martínez & Rosaura Esteve-Puig & Sara García-Ortega & Yuxin Ding & Sara Sánchez-Redondo & Berta Ferrer & Javier Hernandez-Losa & Francesc Canals & Anna Manzano & Aura, 2022. "BRAF activation by metabolic stress promotes glycolysis sensitizing NRASQ61-mutated melanomas to targeted therapy," Nature Communications, Nature, vol. 13(1), pages 1-22, December.
- Mahmoud A. Bassal & Saumya E. Samaraweera & Kelly Lim & Brooks A. Benard & Sheree Bailey & Satinder Kaur & Paul Leo & John Toubia & Chloe Thompson-Peach & Tran Nguyen & Kyaw Ze Ya Maung & Debora A. Ca, 2022. "Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Yimiao Feng & Yahui Long & He Wang & Yang Ouyang & Quan Li & Min Wu & Jie Zheng, 2024. "Benchmarking machine learning methods for synthetic lethality prediction in cancer," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Alon Stern & Mariam Fokra & Boris Sarvin & Ahmad Abed Alrahem & Won Dong Lee & Elina Aizenshtein & Nikita Sarvin & Tomer Shlomi, 2023. "Inferring mitochondrial and cytosolic metabolism by coupling isotope tracing and deconvolution," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- Matthieu Lacroix & Laetitia K. Linares & Natalia Rueda-Rincon & Katarzyna Bloch & Michela Di Michele & Carlo De Blasio & Caroline Fau & Laurie Gayte & Emilie Blanchet & Aline Mairal & Rita Derua & Fer, 2021. "The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
- Qiming Zhou & Yao Peng & Fenfen Ji & Huarong Chen & Wei Kang & Lam-Shing Chan & Hongyan Gou & Yufeng Lin & Pingmei Huang & Danyu Chen & Qinyao Wei & Hao Su & Cong Liang & Xiang Zhang & Jun Yu & Chi Ch, 2023. "Targeting of SLC25A22 boosts the immunotherapeutic response in KRAS-mutant colorectal cancer," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Nazanin Esmaeili Anvar & Chenchu Lin & Xingdi Ma & Lori L. Wilson & Ryan Steger & Annabel K. Sangree & Medina Colic & Sidney H. Wang & John G. Doench & Traver Hart, 2024. "Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-44772-8. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.