p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
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DOI: 10.1038/s41467-022-33945-y
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- B. Colom & A. Herms & M. W. J. Hall & S. C. Dentro & C. King & R. K. Sood & M. P. Alcolea & G. Piedrafita & D. Fernandez-Antoran & S. H. Ong & J. C. Fowler & K. T. Mahbubani & K. Saeb-Parsy & M. Gerst, 2021. "Mutant clones in normal epithelium outcompete and eliminate emerging tumours," Nature, Nature, vol. 598(7881), pages 510-514, October.
- Akira Yokoyama & Nobuyuki Kakiuchi & Tetsuichi Yoshizato & Yasuhito Nannya & Hiromichi Suzuki & Yasuhide Takeuchi & Yusuke Shiozawa & Yusuke Sato & Kosuke Aoki & Soo Ki Kim & Yoichi Fujii & Kenichi Yo, 2019. "Age-related remodelling of oesophageal epithelia by mutated cancer drivers," Nature, Nature, vol. 565(7739), pages 312-317, January.
- Kenichi Yoshida & Kate H. C. Gowers & Henry Lee-Six & Deepak P. Chandrasekharan & Tim Coorens & Elizabeth F. Maughan & Kathryn Beal & Andrew Menzies & Fraser R. Millar & Elizabeth Anderson & Sarah E. , 2020. "Tobacco smoking and somatic mutations in human bronchial epithelium," Nature, Nature, vol. 578(7794), pages 266-272, February.
- Henry Lee-Six & Sigurgeir Olafsson & Peter Ellis & Robert J. Osborne & Mathijs A. Sanders & Luiza Moore & Nikitas Georgakopoulos & Franco Torrente & Ayesha Noorani & Martin Goddard & Philip Robinson &, 2019. "The landscape of somatic mutation in normal colorectal epithelial cells," Nature, Nature, vol. 574(7779), pages 532-537, October.
- Luiza Moore & Daniel Leongamornlert & Tim H. H. Coorens & Mathijs A. Sanders & Peter Ellis & Stefan C. Dentro & Kevin J. Dawson & Tim Butler & Raheleh Rahbari & Thomas J. Mitchell & Francesco Maura & , 2020. "The mutational landscape of normal human endometrial epithelium," Nature, Nature, vol. 580(7805), pages 640-646, April.
- Xi-Xi Chen & Qian Zhong & Yang Liu & Shu-Mei Yan & Zhang-Hua Chen & Shan-Zhao Jin & Tian-Liang Xia & Ruo-Yan Li & Ai-Jun Zhou & Zhe Su & Yu-Hua Huang & Qi-Tao Huang & Li-Yun Huang & Xing Zhang & Yan-N, 2017. "Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing," Nature Communications, Nature, vol. 8(1), pages 1-12, December.
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- Jiaqi Liu & Lijun Dai & Qiang Wang & Chenghao Li & Zhichao Liu & Tongyang Gong & Hengyi Xu & Ziqi Jia & Wanyuan Sun & Xinyu Wang & Minyi Lu & Tongxuan Shang & Ning Zhao & Jiahui Cai & Zhigang Li & Hon, 2024. "Multimodal analysis of cfDNA methylomes for early detecting esophageal squamous cell carcinoma and precancerous lesions," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
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