Mutational landscape of normal epithelial cells in Lynch Syndrome patients
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DOI: 10.1038/s41467-022-29920-2
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- Henry Lee-Six & Sigurgeir Olafsson & Peter Ellis & Robert J. Osborne & Mathijs A. Sanders & Luiza Moore & Nikitas Georgakopoulos & Franco Torrente & Ayesha Noorani & Martin Goddard & Philip Robinson &, 2019. "The landscape of somatic mutation in normal colorectal epithelial cells," Nature, Nature, vol. 574(7779), pages 532-537, October.
- Luiza Moore & Daniel Leongamornlert & Tim H. H. Coorens & Mathijs A. Sanders & Peter Ellis & Stefan C. Dentro & Kevin J. Dawson & Tim Butler & Raheleh Rahbari & Thomas J. Mitchell & Francesco Maura & , 2020. "The mutational landscape of normal human endometrial epithelium," Nature, Nature, vol. 580(7805), pages 640-646, April.
- Sharon Christensen & Bastiaan Roest & Nicolle Besselink & Roel Janssen & Sander Boymans & John W. M. Martens & Marie-Laure Yaspo & Peter Priestley & Ewart Kuijk & Edwin Cuppen & Arne Van Hoeck, 2019. "5-Fluorouracil treatment induces characteristic T>G mutations in human cancer," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
- Francis Blokzijl & Joep de Ligt & Myrthe Jager & Valentina Sasselli & Sophie Roerink & Nobuo Sasaki & Meritxell Huch & Sander Boymans & Ewart Kuijk & Pjotr Prins & Isaac J. Nijman & Inigo Martincorena, 2016. "Tissue-specific mutation accumulation in human adult stem cells during life," Nature, Nature, vol. 538(7624), pages 260-264, October.
- Teh, Yee Whye & Jordan, Michael I. & Beal, Matthew J. & Blei, David M., 2006. "Hierarchical Dirichlet Processes," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 1566-1581, December.
- Ludmil B. Alexandrov & Serena Nik-Zainal & David C. Wedge & Samuel A. J. R. Aparicio & Sam Behjati & Andrew V. Biankin & Graham R. Bignell & Niccolò Bolli & Ake Borg & Anne-Lise Børresen-Dale & Sandri, 2013. "Correction: Corrigendum: Signatures of mutational processes in human cancer," Nature, Nature, vol. 502(7470), pages 258-258, October.
- Ludmil B. Alexandrov & Serena Nik-Zainal & David C. Wedge & Samuel A. J. R. Aparicio & Sam Behjati & Andrew V. Biankin & Graham R. Bignell & Niccolò Bolli & Ake Borg & Anne-Lise Børresen-Dale & Sandri, 2013. "Signatures of mutational processes in human cancer," Nature, Nature, vol. 500(7463), pages 415-421, August.
- Cayetano Pleguezuelos-Manzano & Jens Puschhof & Axel Rosendahl Huber & Arne van Hoeck & Henry M. Wood & Jason Nomburg & Carino Gurjao & Freek Manders & Guillaume Dalmasso & Paul B. Stege & Fernanda L., 2020. "Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli," Nature, Nature, vol. 580(7802), pages 269-273, April.
- Ludmil B. Alexandrov & Jaegil Kim & Nicholas J. Haradhvala & Mi Ni Huang & Alvin Wei Tian Ng & Yang Wu & Arnoud Boot & Kyle R. Covington & Dmitry A. Gordenin & Erik N. Bergstrom & S. M. Ashiqul Islam , 2020. "The repertoire of mutational signatures in human cancer," Nature, Nature, vol. 578(7793), pages 94-101, February.
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