IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v13y2022i1d10.1038_s41467-022-33661-7.html
   My bibliography  Save this article

Bottom-up assembly of viral replication cycles

Author

Listed:
  • Oskar Staufer

    (University of Bristol
    University of Oxford
    Max Planck School Matter to Life)

  • Gösta Gantner

    (Max Planck School Matter to Life
    Heidelberg University)

  • Ilia Platzman

    (University of Bristol
    Max Planck Institute for Medical Research
    University of Heidelberg)

  • Klaus Tanner

    (Max Planck School Matter to Life
    Heidelberg University)

  • Imre Berger

    (University of Bristol
    University of Bristol
    University of Bristol)

  • Joachim P. Spatz

    (University of Bristol
    Max Planck School Matter to Life
    Max Planck Institute for Medical Research
    University of Heidelberg)

Abstract

Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.

Suggested Citation

  • Oskar Staufer & Gösta Gantner & Ilia Platzman & Klaus Tanner & Imre Berger & Joachim P. Spatz, 2022. "Bottom-up assembly of viral replication cycles," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33661-7
    DOI: 10.1038/s41467-022-33661-7
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-022-33661-7
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-022-33661-7?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Omer Adir & Mia R. Albalak & Ravit Abel & Lucien E. Weiss & Gal Chen & Amit Gruber & Oskar Staufer & Yaniv Kurman & Ido Kaminer & Jeny Shklover & Janna Shainsky-Roitman & Ilia Platzman & Lior Gepstein, 2022. "Synthetic cells with self-activating optogenetic proteins communicate with natural cells," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    2. Sara Reardon, 2014. "US suspends risky disease research," Nature, Nature, vol. 514(7523), pages 411-412, October.
    3. Tran Thao & Fabien Labroussaa & Nadine Ebert & Philip V’kovski & Hanspeter Stalder & Jasmine Portmann & Jenna Kelly & Silvio Steiner & Melle Holwerda & Annika Kratzel & Mitra Gultom & Kimberly Schmied, 2020. "Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform," Nature, Nature, vol. 582(7813), pages 561-565, June.
    4. Masaki Imai & Tokiko Watanabe & Masato Hatta & Subash C. Das & Makoto Ozawa & Kyoko Shinya & Gongxun Zhong & Anthony Hanson & Hiroaki Katsura & Shinji Watanabe & Chengjun Li & Eiryo Kawakami & Shinya , 2012. "Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets," Nature, Nature, vol. 486(7403), pages 420-428, June.
    5. Oskar Staufer & Kapil Gupta & Jochen Estebano Hernandez Bücher & Fabian Kohler & Christian Sigl & Gunjita Singh & Kate Vasileiou & Ana Yagüe Relimpio & Meline Macher & Sebastian Fabritz & Hendrik Diet, 2022. "Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    6. Carolina Villarroya-Beltri & Cristina Gutiérrez-Vázquez & Fátima Sánchez-Cabo & Daniel Pérez-Hernández & Jesús Vázquez & Noa Martin-Cofreces & Dannys Jorge Martinez-Herrera & Alberto Pascual-Montano &, 2013. "Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs," Nature Communications, Nature, vol. 4(1), pages 1-10, December.
    7. Tina Wiegand & Marta Fratini & Felix Frey & Klaus Yserentant & Yang Liu & Eva Weber & Kornelia Galior & Julia Ohmes & Felix Braun & Dirk-Peter Herten & Steeve Boulant & Ulrich S. Schwarz & Khalid Sala, 2020. "Forces during cellular uptake of viruses and nanoparticles at the ventral side," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
    8. Steffen Foss Hansen & Martin Krayer von Krauss & Joel A. Tickner, 2008. "The precautionary principle and risk-risk tradeoffs," Journal of Risk Research, Taylor & Francis Journals, vol. 11(4), pages 423-464, June.
    9. Thomas A. Dixon & Paul S. Freemont & Richard A. Johnson & Isak S. Pretorius, 2022. "A global forum on synthetic biology: the need for international engagement," Nature Communications, Nature, vol. 13(1), pages 1-5, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ahmed Kandeil & Christopher Patton & Jeremy C. Jones & Trushar Jeevan & Walter N. Harrington & Sanja Trifkovic & Jon P. Seiler & Thomas Fabrizio & Karlie Woodard & Jasmine C. Turner & Jeri-Carol Crump, 2023. "Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    2. Gita Naseri, 2023. "A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    3. Neng Xia & Dongdong Jin & Chengfeng Pan & Jiachen Zhang & Zhengxin Yang & Lin Su & Jinsheng Zhao & Liu Wang & Li Zhang, 2022. "Dynamic morphological transformations in soft architected materials via buckling instability encoded heterogeneous magnetization," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    4. John D. Graham & Jonathan B. Wiener, 2008. "The precautionary principle and risk--risk tradeoffs: a comment," Journal of Risk Research, Taylor & Francis Journals, vol. 11(4), pages 465-474, June.
    5. Kshitij Wagh & Aatish Bhatia & Benjamin D Greenbaum & Gyan Bhanot, 2014. "Bird to Human Transmission Biases and Vaccine Escape Mutants in H5N1 Infections," PLOS ONE, Public Library of Science, vol. 9(7), pages 1-10, July.
    6. Akshay J. Maheshwari & Jonathan Calles & Sean K. Waterton & Drew Endy, 2023. "Engineering tRNA abundances for synthetic cellular systems," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    7. Bo Qin & Ziheng Li & Kaiming Tang & Tongyun Wang & Yubin Xie & Sylvain Aumonier & Meitian Wang & Shuofeng Yuan & Sheng Cui, 2023. "Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    8. Jamie K. Wardman & Ragnar Löfstedt, 2018. "Anticipating or Accommodating to Public Concern? Risk Amplification and the Politics of Precaution Reexamined," Risk Analysis, John Wiley & Sons, vol. 38(9), pages 1802-1819, September.
    9. Mansour Ebrahimi & Parisa Aghagolzadeh & Narges Shamabadi & Ahmad Tahmasebi & Mohammed Alsharifi & David L Adelson & Farhid Hemmatzadeh & Esmaeil Ebrahimie, 2014. "Understanding the Underlying Mechanism of HA-Subtyping in the Level of Physic-Chemical Characteristics of Protein," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-14, May.
    10. Jonathan Symons & Thomas A. Dixon & Jacqueline Dalziell & Natalie Curach & Ian T. Paulsen & Anthony Wiskich & Isak S. Pretorius, 2024. "Engineering biology and climate change mitigation: Policy considerations," Nature Communications, Nature, vol. 15(1), pages 1-9, December.
    11. Katherine A. Amato & Luis A. Haddock & Katarina M. Braun & Victoria Meliopoulos & Brandi Livingston & Rebekah Honce & Grace A. Schaack & Emma Boehm & Christina A. Higgins & Gabrielle L. Barry & Katia , 2022. "Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    12. Hanyong Jin & Ji-Hyun Yeom & Eunkyoung Shin & Yoonjie Ha & Haifeng Liu & Daeyoung Kim & Minju Joo & Yong-Hak Kim & Hak Kyun Kim & Minkyung Ryu & Hong-Man Kim & Jeongkyu Kim & Keun P. Kim & Yoonsoo Hah, 2024. "5′-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    13. Mutsaers, Inge, 2015. "One-health approach as counter-measure against “autoimmune” responses in biosecurity," Social Science & Medicine, Elsevier, vol. 129(C), pages 123-130.
    14. Yang Liu & Xianwen Zhang & Jianying Liu & Hongjie Xia & Jing Zou & Antonio E. Muruato & Sivakumar Periasamy & Chaitanya Kurhade & Jessica A. Plante & Nathen E. Bopp & Birte Kalveram & Alexander Bukrey, 2022. "A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    15. Xueqing Wang & Quanlong Jiang & Hongdao Zhang & Zhidong He & Yuanyuan Song & Yifan Chen & Na Tang & Yifei Zhou & Yiping Li & Adam Antebi & Ligang Wu & Jing-Dong J. Han & Yidong Shen, 2024. "Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    16. G. Tuba Barut & Nico Joel Halwe & Adriano Taddeo & Jenna N. Kelly & Jacob Schön & Nadine Ebert & Lorenz Ulrich & Christelle Devisme & Silvio Steiner & Bettina Salome Trüeb & Bernd Hoffmann & Inês Bere, 2022. "The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    17. Xi Zhang & Te Zhang & Xin Wei & Zhanpeng Xiao & Weiwen Zhang, 2024. "Reducing potential dual-use risks in synthetic biology laboratory research: a dynamic model of analysis," Palgrave Communications, Palgrave Macmillan, vol. 11(1), pages 1-14, December.
    18. Bin Yu & Hekai Li & Zhaowenbin Zhang & Peier Chen & Ling Wang & Xianglin Fan & Xiaodong Ning & Yuxuan Pan & Feiran Zhou & Xinyi Hu & Jiang Chang & Caiwen Ou, 2023. "Extracellular vesicles engineering by silicates-activated endothelial progenitor cells for myocardial infarction treatment in male mice," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
    19. Laura Matrajt & M Elizabeth Halloran & Ira M Longini Jr, 2013. "Optimal Vaccine Allocation for the Early Mitigation of Pandemic Influenza," PLOS Computational Biology, Public Library of Science, vol. 9(3), pages 1-15, March.
    20. Guilherme Dias de Melo & Victoire Perraud & Flavio Alvarez & Alba Vieites-Prado & Seonhee Kim & Lauriane Kergoat & Anthony Coleon & Bettina Salome Trüeb & Magali Tichit & Aurèle Piazza & Agnès Thierry, 2023. "Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33661-7. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.