IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i7p3803-d777593.html
   My bibliography  Save this article

The Effect of Deep Micro Vibrotactile Stimulation on Cognitive Function of Mild Cognitive Impairment and Mild Dementia

Author

Listed:
  • Ayuto Kodama

    (Advanced Research Center for Geriatric and Gerontology, Akita University, Akita 010-8543, Japan)

  • Yasuhiro Suzuki

    (Department of Complex Systems Science, Graduate School of Information Science, Nagoya University, Nagoya 464-8601, Japan)

  • Kazuki Sakuraba

    (Home-Visit Nursing Station Gotenmari, Yurihonjo 018-1301, Japan)

  • Yu Kume

    (Department of Occupational Therapy, Graduate school of Medicine, Akita University, Akita 010-8543, Japan)

  • Hidetaka Ota

    (Advanced Research Center for Geriatric and Gerontology, Akita University, Akita 010-8543, Japan)

Abstract

Background: The purpose of this study was to clarify the effect of Deep Micro Vibrotactile (DMV) stimulation on the cognitive functions in elderly people with mild cognitive impairment or mild dementia. Methods: A total of 35 participants with dementia from three nursing homes, who had completed treatment with DMV stimulation at 15–40 Hz (hereinafter, 15–40 Hz DMV stimulation) for a month were recruited for this study. The subjects had received continuous 15–40 Hz DMV stimulation for 24 h a day for 1 month. We assessed the effect of the treatment on the cognitive functions (by the word list memory (WM) test, trail making test-part A (TMT-A) and part B (TMT-B), and symbol digit substitution task (SDST)) and physical functions (grip strength (GS) and usual walking speed (UWS)), by comparing the results at the baseline and after the 1-month intervention (DMV stimulation). Results: The results revealed that the performances in the WM test ( p < 0.05), TMT-B ( p < 0.05), and SDST ( p < 0.01) improved significantly after the intervention. Conclusion: Our findings suggest that 15–40 Hz DMV stimulation is might be effective for improving the cognitive functions in elderly people with dementia. Furthermore, our novel findings showed the different effectiveness of the treatment depending on the stage of cognitive impairments.

Suggested Citation

  • Ayuto Kodama & Yasuhiro Suzuki & Kazuki Sakuraba & Yu Kume & Hidetaka Ota, 2022. "The Effect of Deep Micro Vibrotactile Stimulation on Cognitive Function of Mild Cognitive Impairment and Mild Dementia," IJERPH, MDPI, vol. 19(7), pages 1-10, March.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:7:p:3803-:d:777593
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/7/3803/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/19/7/3803/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Rebecca G. Canter & Jay Penney & Li-Huei Tsai, 2016. "The road to restoring neural circuits for the treatment of Alzheimer's disease," Nature, Nature, vol. 539(7628), pages 187-196, November.
    2. Hannah F. Iaccarino & Annabelle C. Singer & Anthony J. Martorell & Andrii Rudenko & Fan Gao & Tyler Z. Gillingham & Hansruedi Mathys & Jinsoo Seo & Oleg Kritskiy & Fatema Abdurrob & Chinnakkaruppan Ad, 2016. "Gamma frequency entrainment attenuates amyloid load and modifies microglia," Nature, Nature, vol. 540(7632), pages 230-235, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ana Sofía Ríos & Simón Oxenford & Clemens Neudorfer & Konstantin Butenko & Ningfei Li & Nanditha Rajamani & Alexandre Boutet & Gavin J. B. Elias & Jurgen Germann & Aaron Loh & Wissam Deeb & Fuyixue Wa, 2022. "Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer’s disease," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    2. Ankita Sengupta & Sanjna Banerjee & Suhas Ganesh & Shrey Grover & Devarajan Sridharan, 2024. "The right posterior parietal cortex mediates spatial reorienting of attentional choice bias," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    3. Daniela Rodrigues-Amorim & P. Lorenzo Bozzelli & TaeHyun Kim & Liwang Liu & Oliver Gibson & Cheng-Yi Yang & Mitchell H. Murdock & Fabiola Galiana-Melendez & Brooke Schatz & Alexis Davison & Md Rezaul , 2024. "Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    4. Amy Clements-Cortes & Lee Bartel, 2022. "Long-Term Multi-Sensory Gamma Stimulation of Dementia Patients: A Case Series Report," IJERPH, MDPI, vol. 19(23), pages 1-10, November.
    5. Koustav Roy & Xuzhao Zhou & Rintaro Otani & Ping-Chuan Yuan & Shuji Ioka & Kaspar E. Vogt & Tamae Kondo & Nouran H. T. Farag & Haruto Ijiri & Zhaofa Wu & Youhei Chitose & Mao Amezawa & David S. Uygun , 2024. "Optochemical control of slow-wave sleep in the nucleus accumbens of male mice by a photoactivatable allosteric modulator of adenosine A2A receptors," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    6. Li, Huixia & Zhao, Hongyong, 2022. "Mathematical model of Alzheimer’s disease with prion proteins interactions and treatment," Applied Mathematics and Computation, Elsevier, vol. 433(C).
    7. Lou T. Blanpain & Eric R. Cole & Emily Chen & James K. Park & Michael Y. Walelign & Robert E. Gross & Brian T. Cabaniss & Jon T. Willie & Annabelle C. Singer, 2024. "Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
    8. Qingtao Sun & Jianping Zhang & Anan Li & Mei Yao & Guangcai Liu & Siqi Chen & Yue Luo & Zhi Wang & Hui Gong & Xiangning Li & Qingming Luo, 2022. "Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer’s disease," Nature Communications, Nature, vol. 13(1), pages 1-22, December.
    9. Qian Wang & Yusheng Zhang & Haoyue Xue & Yushun Zeng & Gengxi Lu & Hongsong Fan & Laiming Jiang & Jiagang Wu, 2024. "Lead-free dual-frequency ultrasound implants for wireless, biphasic deep brain stimulation," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    10. Thenille Braun Janzen & Denise Paneduro & Larry Picard & Allan Gordon & Lee R Bartel, 2019. "A parallel randomized controlled trial examining the effects of rhythmic sensory stimulation on fibromyalgia symptoms," PLOS ONE, Public Library of Science, vol. 14(3), pages 1-19, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:7:p:3803-:d:777593. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.