IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v17y2020i6p1951-d333275.html
   My bibliography  Save this article

Simultaneous Analysis and Dietary Exposure Risk Assessment of Fomesafen, Clomazone, Clethodim and Its Two Metabolites in Soybean Ecosystem

Author

Listed:
  • Kyongjin Pang

    (School of Chemistry and Biological Engineering, University of Science Technology Beijing, Beijing 100083, China)

  • Jiye Hu

    (School of Chemistry and Biological Engineering, University of Science Technology Beijing, Beijing 100083, China)

Abstract

A commercial formulation, 37% dispersible oil suspension (DOS) (fomesafen, clomazone, and clethodim), is being registered in China to control annual or perennial weeds in soybean fields. In this paper, a liquid chromatography tandem mass spectrometry method with QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation was developed for the simultaneous determination of fomesafen, clomazone, clethodim, and its two metabolites (CSO and CSO 2 ) in soybean, green soybean, and soybean straw samples. The mean recoveries of our developed method for the five analytes in three matrices were ranged from 71% to 116% with relative standard deviations (RSDs) less than 12.6%. The limits of quantification (LOQs) were 0.01 mg/kg in soybean, 0.01 mg/kg in green soybean, and 0.02 mg/kg in soybean straw while the limits of detection (LODs) ranged from 0.018 to 0.125 μg/kg for these five analytes. The highest final residual amount of CSO 2 in green soybean samples (0.015 mg/kg) appeared in Anhui, and the highest in soybean straw samples was 0.029 mg/kg in Guangxi, whilst the terminal residues of fomesafen, clomazone, clethodim and CSO were lower than LOQs (0.01 mg/kg) in all samples. Furthermore, these terminal residues were all lower than the maximum residue limits (MRLs) set by China (0.1 mg/kg for fomesafen and clethodim, 0.05 mg/kg for clomazone) at harvest. Additional chronic dietary risk was evaluated using a risk quotients (RQs) method based on Chinese dietary habits. The chronic dietary exposure risk quotients were 4.3 for fomesafen, 0.12 for clomazone, and 19.3 for clethodim, respectively, which were significantly lower than 100. These results demonstrated that the dietary exposure risk of fomesafen, clomazone, and clethodim used in soybean according to good agricultural practices (GAP) was acceptable and would not pose an unacceptable health risk to Chinese consumers. These results not only offer insight with respect to the analytes, but also contribute to environmental protection and food safety.

Suggested Citation

  • Kyongjin Pang & Jiye Hu, 2020. "Simultaneous Analysis and Dietary Exposure Risk Assessment of Fomesafen, Clomazone, Clethodim and Its Two Metabolites in Soybean Ecosystem," IJERPH, MDPI, vol. 17(6), pages 1-14, March.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:6:p:1951-:d:333275
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/17/6/1951/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/17/6/1951/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Christos A. Damalas & Ilias G. Eleftherohorinos, 2011. "Pesticide Exposure, Safety Issues, and Risk Assessment Indicators," IJERPH, MDPI, vol. 8(5), pages 1-18, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mingyue Li & Jingjing Wang & Kai Chen & Lianbei Wu, 2020. "Willingness and Behaviors of Farmers’ Green Disposal of Pesticide Packaging Waste in Henan, China: A Perceived Value Formation Mechanism Perspective," IJERPH, MDPI, vol. 17(11), pages 1-18, May.
    2. Ivana Doležalová & Irena Petrželová & Martin Duchoslav, 2020. "Selectivity and efficacy of herbicides dimethachlor and pethoxamid in rocket crop," Plant Protection Science, Czech Academy of Agricultural Sciences, vol. 56(4), pages 305-316.
    3. Vdovenko, Natalia & Tomilin, Oleksii & Kovalenko, Liubov & Badri, Gechbaia & Konchakovskiy, Eugen, 2022. "Global trends and development prospects of the market of plant protection products," Agricultural and Resource Economics: International Scientific E-Journal, Agricultural and Resource Economics: International Scientific E-Journal, vol. 8(2), June.
    4. Liza Oates & Marc Cohen, 2011. "Assessing Diet as a Modifiable Risk Factor for Pesticide Exposure," IJERPH, MDPI, vol. 8(6), pages 1-13, May.
    5. Salvatore Privitera & Emanuele Cerruto & Giuseppe Manetto & Sebastian Lupica & David Nuyttens & Donald Dekeyser & Ingrid Zwertvaegher & Marconi Ribeiro Furtado Júnior & Beatriz Costalonga Vargas, 2024. "Comparison between Liquid Immersion, Laser Diffraction, PDPA, and Shadowgraphy in Assessing Droplet Size from Agricultural Nozzles," Agriculture, MDPI, vol. 14(7), pages 1-21, July.
    6. Xiaolong Sun & Jing Lyu & Candi Ge, 2022. "Knowledge and Farmers’ Adoption of Green Production Technologies: An Empirical Study on IPM Adoption Intention in Major Indica-Rice-Producing Areas in the Anhui Province of China," IJERPH, MDPI, vol. 19(21), pages 1-16, November.
    7. Carina Lackmann & Antonio Šimić & Sandra Ečimović & Alma Mikuška & Thomas-Benjamin Seiler & Henner Hollert & Mirna Velki, 2023. "Subcellular Responses and Avoidance Behavior in Earthworm Eisenia andrei Exposed to Pesticides in the Artificial Soil," Agriculture, MDPI, vol. 13(2), pages 1-15, January.
    8. M. Imran Ganaie & Manzoor A. Wani & Aisha Dev & Ishtiaq A. Mayer, 2022. "Pesticide exposure of farm community causing illness symptoms in upper Jhelum Basin of Kashmir Himalaya, India," Environment, Development and Sustainability: A Multidisciplinary Approach to the Theory and Practice of Sustainable Development, Springer, vol. 24(12), pages 13771-13785, December.
    9. Wijdane Rhioui & Jamila Al Figuigui & Rachid Lahlali & Salah-Eddine Laasli & Abdellatif Boutagayout & Moussa El Jarroudi & Saâdia Belmalha, 2023. "Towards Sustainable Vegetable Farming: Exploring Agroecological Alternatives to Chemical Products in the Fez-Meknes Region of Morocco," Sustainability, MDPI, vol. 15(9), pages 1-23, April.
    10. Marina Teófilo Pignati & Juarez Carlos Brito Pezzuti & Larissa Costa de Souza & Marcelo De Oliveira Lima & Wanderlei Antonio Pignati & Rosivaldo De Alcântara Mendes, 2018. "Assessment of Mercury Concentration in Turtles ( Podocnemis unifilis ) in the Xingu River Basin, Brazil," IJERPH, MDPI, vol. 15(6), pages 1-11, June.
    11. Shah Rome Khan & Muhammad Imran Khan & Dr. Sardar Javaid Iqbal Khan, 2023. "An Investigation into the Statistical Significance of Labor Force Longevity in Brick Kilns and Marble Industry: A Case Study of Peshawar," Journal of Policy Research (JPR), Research Foundation for Humanity (RFH), vol. 9(2), pages 679-688.
    12. Benjamin Ndayambaje & Hellen Amuguni & Jeanne Coffin-Schmitt & Nancy Sibo & Martin Ntawubizi & Elizabeth VanWormer, 2019. "Pesticide Application Practices and Knowledge among Small-Scale Local Rice Growers and Communities in Rwanda: A Cross-Sectional Study," IJERPH, MDPI, vol. 16(23), pages 1-11, November.
    13. Asghar Bagheri & Naier Emami & Christos A. Damalas, 2023. "Monitoring point source pollution by pesticide use: an analysis of farmers’ environmental behavior in waste disposal," Environment, Development and Sustainability: A Multidisciplinary Approach to the Theory and Practice of Sustainable Development, Springer, vol. 25(7), pages 6711-6726, July.
    14. Ming Ye & Jeremy Beach & Jonathan W. Martin & Ambikaipakan Senthilselvan, 2013. "Occupational Pesticide Exposures and Respiratory Health," IJERPH, MDPI, vol. 10(12), pages 1-30, November.
    15. Maryam Pishgar & Salah Fuad Issa & Margaret Sietsema & Preethi Pratap & Houshang Darabi, 2021. "REDECA: A Novel Framework to Review Artificial Intelligence and Its Applications in Occupational Safety and Health," IJERPH, MDPI, vol. 18(13), pages 1-42, June.
    16. Huaquan Zhang & Zhenyao Yang & Yidan Wang & Martinson Ankrah Twumasi & Abbas Ali Chandio, 2023. "Impact of Agricultural Mechanization Level on Farmers’ Health Status in Western China: Analysis Based on CHARLS Data," IJERPH, MDPI, vol. 20(5), pages 1-20, March.
    17. Ishmael Kosamu & Chikumbusko Kaonga & Wells Utembe, 2020. "A Critical Review of the Status of Pesticide Exposure Management in Malawi," IJERPH, MDPI, vol. 17(18), pages 1-13, September.
    18. Joel Salazar-Flores & Sarah M. Lomelí-Martínez & Hazael R. Ceja-Gálvez & Juan H. Torres-Jasso & Luis A. Torres-Reyes & Erandis D. Torres-Sánchez, 2022. "Impacts of Pesticides on Oral Cavity Health and Ecosystems: A Review," IJERPH, MDPI, vol. 19(18), pages 1-20, September.
    19. Lisa Chedik & Dominique Mias-Lucquin & Arnaud Bruyere & Olivier Fardel, 2017. "In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans," IJERPH, MDPI, vol. 14(7), pages 1-17, June.
    20. Ratana Sapbamrer & Jiraporn Chittrakul, 2022. "Determinants of Consumers’ Behavior in Reducing Pesticide Residues in Vegetables and Fruits, Northern Thailand," IJERPH, MDPI, vol. 19(20), pages 1-11, October.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:17:y:2020:i:6:p:1951-:d:333275. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.