IDEAS home Printed from https://ideas.repec.org/a/eee/stapro/v136y2018icp30-33.html
   My bibliography  Save this article

Big data and biostatistics: The death of the asymptotic Valhalla

Author

Listed:
  • Wit, Ernst C.

Abstract

Despite the ubiquity of Big Data in the modern scientific discourse, most references describe storage and query considerations and rarely full-flexed analyses. In this article, we propose another definition with particular relevance to biometrics. We argue that the complexity of the generating measure of biological process means that the model complexity of any statistical model will have to be smaller. Only, when the model is used for prediction can we have any hope that the number of available features reasonably outnumbers the desired complexity of the model.

Suggested Citation

  • Wit, Ernst C., 2018. "Big data and biostatistics: The death of the asymptotic Valhalla," Statistics & Probability Letters, Elsevier, vol. 136(C), pages 30-33.
    • Handle: RePEc:eee:stapro:v:136:y:2018:i:c:p:30-33
    DOI: 10.1016/j.spl.2018.02.039
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167715218300841
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.spl.2018.02.039?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Luigi Augugliaro & Angelo M. Mineo & Ernst C. Wit, 2016. "A differential-geometric approach to generalized linear models with grouped predictors," Biometrika, Biometrika Trust, vol. 103(3), pages 563-577.
    2. Fan J. & Li R., 2001. "Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1348-1360, December.
    3. Ernst Wit & Edwin van den Heuvel & Jan-Willem Romeijn, 2012. "‘All models are wrong...’: an introduction to model uncertainty," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 66(3), pages 217-236, August.
    4. Hui Zou & Trevor Hastie, 2005. "Addendum: Regularization and variable selection via the elastic net," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 67(5), pages 768-768, November.
    5. Hui Zou & Trevor Hastie, 2005. "Regularization and variable selection via the elastic net," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 67(2), pages 301-320, April.
    6. Luigi Augugliaro & Angelo M. Mineo & Ernst C. Wit, 2013. "Differential geometric least angle regression: a differential geometric approach to sparse generalized linear models," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 75(3), pages 471-498, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Tutz, Gerhard & Pößnecker, Wolfgang & Uhlmann, Lorenz, 2015. "Variable selection in general multinomial logit models," Computational Statistics & Data Analysis, Elsevier, vol. 82(C), pages 207-222.
    2. Shuichi Kawano, 2014. "Selection of tuning parameters in bridge regression models via Bayesian information criterion," Statistical Papers, Springer, vol. 55(4), pages 1207-1223, November.
    3. Qianyun Li & Runmin Shi & Faming Liang, 2019. "Drug sensitivity prediction with high-dimensional mixture regression," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-18, February.
    4. Soave, David & Lawless, Jerald F., 2023. "Regularized regression for two phase failure time studies," Computational Statistics & Data Analysis, Elsevier, vol. 182(C).
    5. Zemin Zheng & Jie Zhang & Yang Li, 2022. "L 0 -Regularized Learning for High-Dimensional Additive Hazards Regression," INFORMS Journal on Computing, INFORMS, vol. 34(5), pages 2762-2775, September.
    6. Umberto Amato & Anestis Antoniadis & Italia De Feis & Irene Gijbels, 2021. "Penalised robust estimators for sparse and high-dimensional linear models," Statistical Methods & Applications, Springer;Società Italiana di Statistica, vol. 30(1), pages 1-48, March.
    7. Zichen Zhang & Ye Eun Bae & Jonathan R. Bradley & Lang Wu & Chong Wu, 2022. "SUMMIT: An integrative approach for better transcriptomic data imputation improves causal gene identification," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    8. Wang, Christina Dan & Chen, Zhao & Lian, Yimin & Chen, Min, 2022. "Asset selection based on high frequency Sharpe ratio," Journal of Econometrics, Elsevier, vol. 227(1), pages 168-188.
    9. Bartosz Uniejewski, 2024. "Regularization for electricity price forecasting," Papers 2404.03968, arXiv.org.
    10. Peter Bühlmann & Jacopo Mandozzi, 2014. "High-dimensional variable screening and bias in subsequent inference, with an empirical comparison," Computational Statistics, Springer, vol. 29(3), pages 407-430, June.
    11. Capanu, Marinela & Giurcanu, Mihai & Begg, Colin B. & Gönen, Mithat, 2023. "Subsampling based variable selection for generalized linear models," Computational Statistics & Data Analysis, Elsevier, vol. 184(C).
    12. Ander Wilson & Brian J. Reich, 2014. "Confounder selection via penalized credible regions," Biometrics, The International Biometric Society, vol. 70(4), pages 852-861, December.
    13. Loann David Denis Desboulets, 2018. "A Review on Variable Selection in Regression Analysis," Econometrics, MDPI, vol. 6(4), pages 1-27, November.
    14. Zeyu Bian & Erica E. M. Moodie & Susan M. Shortreed & Sahir Bhatnagar, 2023. "Variable selection in regression‐based estimation of dynamic treatment regimes," Biometrics, The International Biometric Society, vol. 79(2), pages 988-999, June.
    15. Lee, Ji Hyung & Shi, Zhentao & Gao, Zhan, 2022. "On LASSO for predictive regression," Journal of Econometrics, Elsevier, vol. 229(2), pages 322-349.
    16. Ian W. McKeague & Min Qian, 2015. "An Adaptive Resampling Test for Detecting the Presence of Significant Predictors," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 110(512), pages 1422-1433, December.
    17. Victor Chernozhukov & Christian Hansen & Yuan Liao, 2015. "A lava attack on the recovery of sums of dense and sparse signals," CeMMAP working papers CWP56/15, Centre for Microdata Methods and Practice, Institute for Fiscal Studies.
    18. Simona Buscemi & Antonella Plaia, 2020. "Model selection in linear mixed-effect models," AStA Advances in Statistical Analysis, Springer;German Statistical Society, vol. 104(4), pages 529-575, December.
    19. Yongjin Li & Qingzhao Zhang & Qihua Wang, 2017. "Penalized estimation equation for an extended single-index model," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 69(1), pages 169-187, February.
    20. Yang, Yanlin & Hu, Xuemei & Jiang, Huifeng, 2022. "Group penalized logistic regressions predict up and down trends for stock prices," The North American Journal of Economics and Finance, Elsevier, vol. 59(C).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:stapro:v:136:y:2018:i:c:p:30-33. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/wps/find/journaldescription.cws_home/622892/description#description .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.