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Theoretical biophysical approach to cross-linking effects on eyes pressure

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  • Lucia, Umberto
  • Grisolia, Giulia
  • Francia, Sabrina
  • Astori, Mariarosa

Abstract

In 1998, corneal collagen cross-linking was first proposed as a treatment modality to stabilize the ectatic cornea. The pressure inside the eyes anterior chamber (IOP), the elastic properties of the cornea, and the related refractive properties of the eye were demonstrated to be dependent on the temperature of the ocular anterior chamber. In this paper the IOP related to the cross linking therapy is analysed in order to understand the possible consequences of the UV irradiation of the cornea in relation to any possible increase of the IOP. The results obtained highlight that an increase of the IOP occurs, but it returns back to the patients normal values.

Suggested Citation

  • Lucia, Umberto & Grisolia, Giulia & Francia, Sabrina & Astori, Mariarosa, 2019. "Theoretical biophysical approach to cross-linking effects on eyes pressure," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 534(C).
    • Handle: RePEc:eee:phsmap:v:534:y:2019:i:c:s0378437119312555
    DOI: 10.1016/j.physa.2019.122163
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    References listed on IDEAS

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    1. Lucia, Umberto & Grisolia, Giulia & Ponzetto, Antonio & Deisboeck, Thomas S., 2018. "Thermodynamic considerations on the role of heat and mass transfer in biochemical causes of carcinogenesis," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 490(C), pages 1164-1170.
    2. Razmara, M. & Bidarvatan, M. & Shahbakhti, M. & Robinett, R.D., 2016. "Optimal exergy-based control of internal combustion engines," Applied Energy, Elsevier, vol. 183(C), pages 1389-1403.
    3. Hajmohammadi, M.R. & Haji Molla Ali Tork, M.H., 2019. "Effects of the magnetic field on the cylindrical Couette flow and heat transfer of a nanofluid," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 523(C), pages 234-245.
    4. Hajmohammadi, M.R. & Toghraei, I., 2018. "Optimal design and thermal performance improvement of a double-layered microchannel heat sink by introducing Al2O3 nano-particles into the water," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 505(C), pages 328-344.
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