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Structural brain imaging correlates of general intelligence in UK Biobank

Author

Listed:
  • Cox, S.R.
  • Ritchie, S.J.
  • Fawns-Ritchie, C.
  • Tucker-Drob, E.M.
  • Deary, I.J.

Abstract

The associations between indices of brain structure and measured intelligence are unclear. This is partly because the evidence to-date comes from mostly small and heterogeneous studies. Here, we report brain structure-intelligence associations on a large sample from the UK Biobank study. The overall N = 29,004, with N = 18,426 participants providing both brain MRI and at least one cognitive test, and a complete four-test battery with MRI data available in a minimum N = 7201, depending upon the MRI measure. Participants' age range was 44–81 years (M = 63.13, SD = 7.48). A general factor of intelligence (g) was derived from four varied cognitive tests, accounting for one third of the variance in the cognitive test scores. The association between (age- and sex- corrected) total brain volume and a latent factor of general intelligence is r = 0.276, 95% C.I. = [0.252, 0.300]. A model that incorporated multiple global measures of grey and white matter macro- and microstructure accounted for more than double the g variance in older participants compared to those in middle-age (13.6% and 5. 4%, respectively). There were no sex differences in the magnitude of associations between g and total brain volume or other global aspects of brain structure. The largest brain regional correlates of g were volumes of the insula, frontal, anterior/superior and medial temporal, posterior and paracingulate, lateral occipital cortices, thalamic volume, and the white matter microstructure of thalamic and association fibres, and of the forceps minor. Many of these regions exhibited unique contributions to intelligence, and showed highly stable out of sample prediction.

Suggested Citation

  • Cox, S.R. & Ritchie, S.J. & Fawns-Ritchie, C. & Tucker-Drob, E.M. & Deary, I.J., 2019. "Structural brain imaging correlates of general intelligence in UK Biobank," Intelligence, Elsevier, vol. 76(C), pages 1-1.
    • Handle: RePEc:eee:intell:v:76:y:2019:i:c:9
    DOI: 10.1016/j.intell.2019.101376
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    1. Donald M Lyall & Breda Cullen & Mike Allerhand & Daniel J Smith & Daniel Mackay & Jonathan Evans & Jana Anderson & Chloe Fawns-Ritchie & Andrew M McIntosh & Ian J Deary & Jill P Pell, 2016. "Cognitive Test Scores in UK Biobank: Data Reduction in 480,416 Participants and Longitudinal Stability in 20,346 Participants," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-10, April.
    2. MacPherson, Sarah E. & Allerhand, Michael & Cox, Simon R. & Deary, Ian J., 2019. "Individual differences in cognitive processes underlying Trail Making Test-B performance in old age: The Lothian Birth Cohort 1936," Intelligence, Elsevier, vol. 75(C), pages 23-32.
    3. Gignac, Gilles E. & Bates, Timothy C., 2017. "Brain volume and intelligence: The moderating role of intelligence measurement quality," Intelligence, Elsevier, vol. 64(C), pages 18-29.
    4. Joseph Henrich & Steven J. Heine & Ara Norenzayan, 2010. "Most people are not WEIRD," Nature, Nature, vol. 466(7302), pages 29-29, July.
    5. Rogier A. Kievit & Simon W. Davis & Daniel J. Mitchell & Jason R. Taylor & John Duncan & Richard N.A. Henson, 2014. "Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking," Nature Communications, Nature, vol. 5(1), pages 1-10, December.
    6. Rosseel, Yves, 2012. "lavaan: An R Package for Structural Equation Modeling," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 48(i02).
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    1. de Souza, Erick Almeida & Silva, Stéphanie Andrade & Vieira, Bruno Hebling & Salmon, Carlos Ernesto Garrido, 2023. "fMRI functional connectivity is a better predictor of general intelligence than cortical morphometric features and ICA parcellation order affects predictive performance," Intelligence, Elsevier, vol. 97(C).
    2. Bruton, Oliver J., 2021. "Is there a “g-neuron”? Establishing a systematic link between general intelligence (g) and the von Economo neuron," Intelligence, Elsevier, vol. 86(C).
    3. Hilger, Kirsten & Spinath, Frank M. & Troche, Stefan & Schubert, Anna-Lena, 2022. "The biological basis of intelligence: Benchmark findings," Intelligence, Elsevier, vol. 93(C).
    4. Vieira, Bruno Hebling & Pamplona, Gustavo Santo Pedro & Fachinello, Karim & Silva, Alice Kamensek & Foss, Maria Paula & Salmon, Carlos Ernesto Garrido, 2022. "On the prediction of human intelligence from neuroimaging: A systematic review of methods and reporting," Intelligence, Elsevier, vol. 93(C).
    5. Danni A. Gadd & Robert F. Hillary & Daniel L. McCartney & Liu Shi & Aleks Stolicyn & Neil A. Robertson & Rosie M. Walker & Robert I. McGeachan & Archie Campbell & Shen Xueyi & Miruna C. Barbu & Claire, 2022. "Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health," Nature Communications, Nature, vol. 13(1), pages 1-14, December.

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