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Convincing the “Herd” of immunity: Lessons from smallpox vaccination in 19th century Germany

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  • Mühlhoff, Katharina

Abstract

Although vaccination is a cost-effective way to control infectious diseases, it is often met with popular resistance. Studying smallpox in 19th century Germany, this paper explores how economic incentives contribute to this phenomenon. The paper adds to the literature by combining mathematical epidemiology and unpublished archival evidence from two German states - Baden and Wurttemberg. The two states are an intriguing case because their initial conditions and vaccination laws were similar. Despite this, Baden experienced lower smallpox prevalence and higher vaccination uptake than Wurttemberg. The epidemiological model predicts that incentives to vaccinate decline rapidly when immunization reduces prevalence. The archival evidence reveals that Baden offset this decline by creating a public vaccination system which reduced costs for vaccinees and vaccinators alike. This suggests that the high fixed costs of centralized immunization policies can be compensated by economies of scale and popular acceptance.

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  • Mühlhoff, Katharina, 2022. "Convincing the “Herd” of immunity: Lessons from smallpox vaccination in 19th century Germany," Economics & Human Biology, Elsevier, vol. 47(C).
  • Handle: RePEc:eee:ehbiol:v:47:y:2022:i:c:s1570677x22000892
    DOI: 10.1016/j.ehb.2022.101193
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    References listed on IDEAS

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    1. Philipp Ager & Casper Worm Hansen & Peter Sandholt Jensen, 2018. "Fertility and Early-Life Mortality: Evidence from Smallpox Vaccination in Sweden," Journal of the European Economic Association, European Economic Association, vol. 16(2), pages 487-521.
    2. Sara Lowes & Eduardo Montero, 2021. "The Legacy of Colonial Medicine in Central Africa," American Economic Review, American Economic Association, vol. 111(4), pages 1284-1314, April.
    3. Mark Gersovitz & Jeffrey S. Hammer, 2004. "The Economical Control of Infectious Diseases," Economic Journal, Royal Economic Society, vol. 114(492), pages 1-27, January.
    4. Olga Krylova & David J D Earn, 2020. "Patterns of smallpox mortality in London, England, over three centuries," PLOS Biology, Public Library of Science, vol. 18(12), pages 1-27, December.
    5. Bonu, Sekhar & Rani, Manju & Baker, Timothy D., 2003. "The impact of the national polio immunization campaign on levels and equity in immunization coverage: evidence from rural North India," Social Science & Medicine, Elsevier, vol. 57(10), pages 1807-1819, November.
    6. Verelst, Frederik & Willem, Lander & Kessels, Roselinde & Beutels, Philippe, 2018. "Individual decisions to vaccinate one's child or oneself: A discrete choice experiment rejecting free-riding motives," Social Science & Medicine, Elsevier, vol. 207(C), pages 106-116.
    7. Mark Gersovitz & Jeffrey S. Hammer, 2003. "Infectious Diseases, Public Policy, and the Marriage of Economics and Epidemiology," The World Bank Research Observer, World Bank, vol. 18(2), pages 129-157.
    8. Wooyoung Lim & Pengfei Zhang, 2020. "Herd immunity and a vaccination game: An experimental study," PLOS ONE, Public Library of Science, vol. 15(5), pages 1-16, May.
    9. Blume, Stuart, 2006. "Anti-vaccination movements and their interpretations," Social Science & Medicine, Elsevier, vol. 62(3), pages 628-642, February.
    10. Gauri, Varun & Khaleghian, Peyvand, 2002. "Immunization in Developing Countries: Its Political and Organizational Determinants," World Development, Elsevier, vol. 30(12), pages 2109-2132, December.
    11. Courtney J. Ward, 2014. "Influenza Vaccination Campaigns: Is an Ounce of Prevention Worth a Pound of Cure?," American Economic Journal: Applied Economics, American Economic Association, vol. 6(1), pages 38-72, January.
    12. Brito, Dagobert L. & Sheshinski, Eytan & Intriligator, Michael D., 1991. "Externalities and compulsary vaccinations," Journal of Public Economics, Elsevier, vol. 45(1), pages 69-90, June.
    13. Colvin, Christopher L. & McLaughlin, Eoin, 2021. "Death, demography and the denominator: Age-adjusted Influenza-18 mortality in Ireland," Economics & Human Biology, Elsevier, vol. 41(C).
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    More about this item

    Keywords

    Health externalities; Vaccination; Smallpox; Vaccine resistance; Regulation; Historical institutions;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health
    • I38 - Health, Education, and Welfare - - Welfare, Well-Being, and Poverty - - - Government Programs; Provision and Effects of Welfare Programs
    • N33 - Economic History - - Labor and Consumers, Demography, Education, Health, Welfare, Income, Wealth, Religion, and Philanthropy - - - Europe: Pre-1913
    • N43 - Economic History - - Government, War, Law, International Relations, and Regulation - - - Europe: Pre-1913

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