IDEAS home Printed from https://ideas.repec.org/a/eee/chsofr/v91y2016icp702-708.html
   My bibliography  Save this article

Dynamic transition on the seizure-like neuronal activity by astrocytic calcium channel block

Author

Listed:
  • Li, Jiajia
  • Wang, Rong
  • Du, Mengmeng
  • Tang, Jun
  • Wu, Ying

Abstract

The involvement of astrocytes in neuronal firing dynamics is becoming increasingly evident. In this study, we used a classical hippocampal tripartite synapse model consisting of soma-dendrite coupled neuron models and a Hodgkin–Huxley-like astrocyte model, to investigate the seizure-like firing in the somatic neuron induced by the over-expressed neuronal N-methyl-d-aspartate (NMDA) receptors. Based on this model, we further investigated the effect of the astrocytic channel block on the neuronal firing through a bifurcation analysis. Results show that blocking inositol-1,4,5-triphosphate(IP3)-dependent calcium channel in astrocytes efficiently suppresses the astrocytic calcium oscillation, which in turn suppresses the seizure-like firing in the neuron.

Suggested Citation

  • Li, Jiajia & Wang, Rong & Du, Mengmeng & Tang, Jun & Wu, Ying, 2016. "Dynamic transition on the seizure-like neuronal activity by astrocytic calcium channel block," Chaos, Solitons & Fractals, Elsevier, vol. 91(C), pages 702-708.
    • Handle: RePEc:eee:chsofr:v:91:y:2016:i:c:p:702-708
    DOI: 10.1016/j.chaos.2016.08.009
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0960077916302466
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.chaos.2016.08.009?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. X. J. Sun & J. Z. Lei & M. Perc & Q. S. Lu & S. J. Lv, 2011. "Effects of channel noise on firing coherence of small-world Hodgkin-Huxley neuronal networks," The European Physical Journal B: Condensed Matter and Complex Systems, Springer;EDP Sciences, vol. 79(1), pages 61-66, January.
    2. Schmid, Gerhard & Goychuk, Igor & Hänggi, Peter, 2004. "Controlling the spiking activity in excitable membranes via poisoning," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 344(3), pages 665-670.
    3. Wang, Qingyun & Perc, Matjaž & Duan, Zhisheng & Chen, Guanrong, 2010. "Impact of delays and rewiring on the dynamics of small-world neuronal networks with two types of coupling," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 389(16), pages 3299-3306.
    4. Wang, Qingyun & Lu, Qishao & Chen, GuanRong & feng, Zhaosheng & Duan, LiXia, 2009. "Bifurcation and synchronization of synaptically coupled FHN models with time delay," Chaos, Solitons & Fractals, Elsevier, vol. 39(2), pages 918-925.
    5. Uzuntarla, Muhammet & Uzun, Rukiye & Yilmaz, Ergin & Ozer, Mahmut & Perc, Matjaž, 2013. "Noise-delayed decay in the response of a scale-free neuronal network," Chaos, Solitons & Fractals, Elsevier, vol. 56(C), pages 202-208.
    6. Ghanim Ullah & Steven J Schiff, 2010. "Assimilating Seizure Dynamics," PLOS Computational Biology, Public Library of Science, vol. 6(5), pages 1-12, May.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Erkan, Erdem & Erkan, Yasemin, 2024. "Effect of autaptic synapse on signal transmission performance of dressed Hodgkin–Huxley neuron," Chaos, Solitons & Fractals, Elsevier, vol. 188(C).
    2. Zhou, Ping & Yao, Zhao & Ma, Jun & Zhu, Zhigang, 2021. "A piezoelectric sensing neuron and resonance synchronization between auditory neurons under stimulus," Chaos, Solitons & Fractals, Elsevier, vol. 145(C).
    3. Li, Xiang & Zhang, Suxia & Liu, Xijun & Wang, Xiaojing & Zhou, Anqi & Liu, Peng, 2018. "Important role of MAMs in bifurcation and coherence resonance of calcium oscillations," Chaos, Solitons & Fractals, Elsevier, vol. 106(C), pages 131-140.
    4. Xiao, Fangli & Fu, Ziying & Jia, Ya & Yang, Lijian, 2023. "Resonance effects in neuronal-astrocyte model with ion channel blockage," Chaos, Solitons & Fractals, Elsevier, vol. 166(C).
    5. Yu, Yangyang & Yuan, Zhixuan & Li, Jiajia & Wu, Ying, 2023. "Dynamic analysis of epileptic seizures caused by energy failure after ischemic stroke," Chaos, Solitons & Fractals, Elsevier, vol. 176(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wu, Hao & Jiang, Huijun & Hou, Zhonghuai, 2011. "Spatiotemporal dynamics on small-world neuronal networks: The roles of two types of time-delayed coupling," Chaos, Solitons & Fractals, Elsevier, vol. 44(10), pages 836-844.
    2. Wang, Qingyun & Zheng, Yanhong & Ma, Jun, 2013. "Cooperative dynamics in neuronal networks," Chaos, Solitons & Fractals, Elsevier, vol. 56(C), pages 19-27.
    3. Uzun, Rukiye & Yilmaz, Ergin & Ozer, Mahmut, 2017. "Effects of autapse and ion channel block on the collective firing activity of Newman–Watts small-world neuronal networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 386-396.
    4. Hao, Yinghang & Gong, Yubing & Wang, Li & Ma, Xiaoguang & Yang, Chuanlu, 2011. "Single or multiple synchronization transitions in scale-free neuronal networks with electrical or chemical coupling," Chaos, Solitons & Fractals, Elsevier, vol. 44(4), pages 260-268.
    5. Xie, Huijuan & Gong, Yubing & Wang, Baoying, 2018. "Spike-timing-dependent plasticity optimized coherence resonance and synchronization transitions by autaptic delay in adaptive scale-free neuronal networks," Chaos, Solitons & Fractals, Elsevier, vol. 108(C), pages 1-7.
    6. Xie, Huijuan & Gong, Yubing, 2017. "Multiple coherence resonances and synchronization transitions by time delay in adaptive scale-free neuronal networks with spike-timing-dependent plasticity," Chaos, Solitons & Fractals, Elsevier, vol. 94(C), pages 80-85.
    7. Uzun, Rukiye, 2017. "Influences of autapse and channel blockage on multiple coherence resonance in a single neuron," Applied Mathematics and Computation, Elsevier, vol. 315(C), pages 203-210.
    8. Yu, Haitao & Wang, Jiang & Liu, Chen & Deng, Bin & Wei, Xile, 2014. "Delay-induced synchronization transitions in modular scale-free neuronal networks with hybrid electrical and chemical synapses," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 405(C), pages 25-34.
    9. Jun Wang & Yongqiang Tian & Lanfeng Hua & Kaibo Shi & Shouming Zhong & Shiping Wen, 2023. "New Results on Finite-Time Synchronization Control of Chaotic Memristor-Based Inertial Neural Networks with Time-Varying Delays," Mathematics, MDPI, vol. 11(3), pages 1-18, January.
    10. Chunni Wang & Shengli Guo & Ying Xu & Jun Ma & Jun Tang & Faris Alzahrani & Aatef Hobiny, 2017. "Formation of Autapse Connected to Neuron and Its Biological Function," Complexity, Hindawi, vol. 2017, pages 1-9, February.
    11. Yu, Haitao & Wang, Jiang & Liu, Qiuxiang & Sun, Jianbing & Yu, Haifeng, 2013. "Delay-induced synchronization transitions in small-world neuronal networks with hybrid synapses," Chaos, Solitons & Fractals, Elsevier, vol. 48(C), pages 68-74.
    12. Suresh, R. & Senthilkumar, D.V. & Lakshmanan, M. & Kurths, J., 2016. "Emergence of a common generalized synchronization manifold in network motifs of structurally different time-delay systems," Chaos, Solitons & Fractals, Elsevier, vol. 93(C), pages 235-245.
    13. Ramírez-Piscina, L. & Sancho, J.M., 2018. "Periodic spiking by a pair of ionic channels," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 505(C), pages 345-354.
    14. Arthur, Joseph & Attarian, Adam & Hamilton, Franz & Tran, Hien, 2018. "Nonlinear Kalman filtering for censored observations," Applied Mathematics and Computation, Elsevier, vol. 316(C), pages 155-166.
    15. Wang, Zhizhi & Hu, Bing & Zhou, Weiting & Xu, Minbo & Wang, Dingjiang, 2023. "Hopf bifurcation mechanism analysis in an improved cortex-basal ganglia network with distributed delays: An application to Parkinson’s disease," Chaos, Solitons & Fractals, Elsevier, vol. 166(C).
    16. Yu, Haitao & Zhang, Lianghao & Guo, Xinmeng & Wang, Jiang & Cao, Yibin & Liu, Jing, 2018. "Effect of inhibitory firing pattern on coherence resonance in random neural networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 490(C), pages 1201-1210.
    17. Gong, Yubing & Xie, Yanhang & Lin, Xiu & Hao, Yinghang & Ma, Xiaoguang, 2010. "Ordering chaos and synchronization transitions by chemical delay and coupling on scale-free neuronal networks," Chaos, Solitons & Fractals, Elsevier, vol. 43(1), pages 96-103.
    18. Guo, Xinmeng & Wang, Jiang & Liu, Jing & Yu, Haitao & Galán, Roberto F. & Cao, Yibin & Deng, Bin, 2017. "Optimal time scales of input fluctuations for spiking coherence and reliability in stochastic Hodgkin–Huxley neurons," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 468(C), pages 381-390.
    19. Madineh Sedigh-Sarvestani & Steven J Schiff & Bruce J Gluckman, 2012. "Reconstructing Mammalian Sleep Dynamics with Data Assimilation," PLOS Computational Biology, Public Library of Science, vol. 8(11), pages 1-15, November.
    20. Rajagopal, Karthikeyan & Jafari, Sajad & Li, Chunbiao & Karthikeyan, Anitha & Duraisamy, Prakash, 2021. "Suppressing spiral waves in a lattice array of coupled neurons using delayed asymmetric synapse coupling," Chaos, Solitons & Fractals, Elsevier, vol. 146(C).

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:chsofr:v:91:y:2016:i:c:p:702-708. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Thayer, Thomas R. (email available below). General contact details of provider: https://www.journals.elsevier.com/chaos-solitons-and-fractals .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.