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Bayesian Modeling for Genetic Anticipation in Presence of Mutational Heterogeneity: A Case Study in Lynch Syndrome

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  • Philip S. Boonstra
  • Bhramar Mukherjee
  • Jeremy M. G. Taylor
  • Mef Nilbert
  • Victor Moreno
  • Stephen B. Gruber

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  • Philip S. Boonstra & Bhramar Mukherjee & Jeremy M. G. Taylor & Mef Nilbert & Victor Moreno & Stephen B. Gruber, 2011. "Bayesian Modeling for Genetic Anticipation in Presence of Mutational Heterogeneity: A Case Study in Lynch Syndrome," Biometrics, The International Biometric Society, vol. 67(4), pages 1627-1637, December.
    • Handle: RePEc:bla:biomet:v:67:y:2011:i:4:p:1627-1637
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    File URL: http://hdl.handle.net/10.1111/j.1541-0420.2011.01607.x
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    References listed on IDEAS

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    1. Verbeke, Geert & Lesaffre, Emmanuel, 1997. "The effect of misspecifying the random-effects distribution in linear mixed models for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 23(4), pages 541-556, February.
    2. Daowen Zhang & Marie Davidian, 2001. "Linear Mixed Models with Flexible Distributions of Random Effects for Longitudinal Data," Biometrics, The International Biometric Society, vol. 57(3), pages 795-802, September.
    3. Daniel Rabinowitz & Qiong Yang, 1999. "Testing for Age-at-Onset Anticipation with Affected Parent-Child Pairs," Biometrics, The International Biometric Society, vol. 55(3), pages 834-838, September.
    4. Hanson, Timothy E., 2006. "Inference for Mixtures of Finite Polya Tree Models," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 1548-1565, December.
    5. Charles E. McCulloch & John M. Neuhaus, 2011. "Prediction of Random Effects in Linear and Generalized Linear Models under Model Misspecification," Biometrics, The International Biometric Society, vol. 67(1), pages 270-279, March.
    6. Larsen Klaus & Petersen Janne & Bernstein Inge & Nilbert Mef, 2009. "A Parametric Model for Analyzing Anticipation in Genetically Predisposed Families," Statistical Applications in Genetics and Molecular Biology, De Gruyter, vol. 8(1), pages 1-13, June.
    7. David J. Spiegelhalter & Nicola G. Best & Bradley P. Carlin & Angelika Van Der Linde, 2002. "Bayesian measures of model complexity and fit," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(4), pages 583-639, October.
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