IDEAS home Printed from https://ideas.repec.org/a/taf/japsta/v39y2012i5p1087-1100.html
   My bibliography  Save this article

Bayesian analysis of longitudinal ordered data with flexible random effects using McMC: application to diabetic macular Edema data

Author

Listed:
  • Marjan Mansourian
  • Anoshirvan Kazemnejad
  • Iraj Kazemi
  • Farid Zayeri
  • Masoud Soheilian

Abstract

In the analysis of correlated ordered data, mixed-effect models are frequently used to control the subject heterogeneity effects. A common assumption in fitting these models is the normality of random effects. In many cases, this is unrealistic, making the estimation results unreliable. This paper considers several flexible models for random effects and investigates their properties in the model fitting. We adopt a proportional odds logistic regression model and incorporate the skewed version of the normal, Student's t and slash distributions for the effects. Stochastic representations for various flexible distributions are proposed afterwards based on the mixing strategy approach. This reduces the computational burden being performed by the McMC technique. Furthermore, this paper addresses the identifiability restrictions and suggests a procedure to handle this issue. We analyze a real data set taken from an ophthalmic clinical trial. Model selection is performed by suitable Bayesian model selection criteria.

Suggested Citation

  • Marjan Mansourian & Anoshirvan Kazemnejad & Iraj Kazemi & Farid Zayeri & Masoud Soheilian, 2012. "Bayesian analysis of longitudinal ordered data with flexible random effects using McMC: application to diabetic macular Edema data," Journal of Applied Statistics, Taylor & Francis Journals, vol. 39(5), pages 1087-1100, November.
  • Handle: RePEc:taf:japsta:v:39:y:2012:i:5:p:1087-1100
    DOI: 10.1080/02664763.2011.638367
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.1080/02664763.2011.638367
    Download Restriction: Access to full text is restricted to subscribers.

    File URL: https://libkey.io/10.1080/02664763.2011.638367?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Verbeke, Geert & Lesaffre, Emmanuel, 1997. "The effect of misspecifying the random-effects distribution in linear mixed models for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 23(4), pages 541-556, February.
    2. David J. Spiegelhalter & Nicola G. Best & Bradley P. Carlin & Angelika Van Der Linde, 2002. "Bayesian measures of model complexity and fit," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(4), pages 583-639, October.
    3. G. J. M. Rosa & D. Gianola & C. R. Padovani, 2004. "Bayesian Longitudinal Data Analysis with Mixed Models and Thick-tailed Distributions using MCMC," Journal of Applied Statistics, Taylor & Francis Journals, vol. 31(7), pages 855-873.
    4. A. Azzalini & A. Capitanio, 1999. "Statistical applications of the multivariate skew normal distribution," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 61(3), pages 579-602.
    5. Daowen Zhang & Marie Davidian, 2001. "Linear Mixed Models with Flexible Distributions of Random Effects for Longitudinal Data," Biometrics, The International Biometric Society, vol. 57(3), pages 795-802, September.
    6. Arellano-Valle, Reinaldo B. & Genton, Marc G., 2005. "On fundamental skew distributions," Journal of Multivariate Analysis, Elsevier, vol. 96(1), pages 93-116, September.
    7. Jara, Alejandro & Quintana, Fernando & San Marti­n, Ernesto, 2008. "Linear mixed models with skew-elliptical distributions: A Bayesian approach," Computational Statistics & Data Analysis, Elsevier, vol. 52(11), pages 5033-5045, July.
    8. Arslan, Olcay, 2008. "An alternative multivariate skew-slash distribution," Statistics & Probability Letters, Elsevier, vol. 78(16), pages 2756-2761, November.
    9. Gómez, Héctor W. & Quintana, Fernando A. & Torres, Francisco J., 2007. "A new family of slash-distributions with elliptical contours," Statistics & Probability Letters, Elsevier, vol. 77(7), pages 717-725, April.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Liao, Xin & Peng, Zuoxiang & Nadarajah, Saralees, 2013. "Asymptotic expansions for moments of skew-normal extremes," Statistics & Probability Letters, Elsevier, vol. 83(5), pages 1321-1329.
    2. Liao, Xin & Peng, Zuoxiang & Nadarajah, Saralees & Wang, Xiaoqian, 2014. "Rates of convergence of extremes from skew-normal samples," Statistics & Probability Letters, Elsevier, vol. 84(C), pages 40-47.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Jara, Alejandro & Quintana, Fernando & San Marti­n, Ernesto, 2008. "Linear mixed models with skew-elliptical distributions: A Bayesian approach," Computational Statistics & Data Analysis, Elsevier, vol. 52(11), pages 5033-5045, July.
    2. Reyhaneh Rikhtehgaran & Iraj Kazemi, 2013. "Semi-parametric Bayesian estimation of mixed-effects models using the multivariate skew-normal distribution," Computational Statistics, Springer, vol. 28(5), pages 2007-2027, October.
    3. Hanze Zhang & Yangxin Huang, 2020. "Quantile regression-based Bayesian joint modeling analysis of longitudinal–survival data, with application to an AIDS cohort study," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(2), pages 339-368, April.
    4. M. Teimourian & T. Baghfalaki & M. Ganjali & D. Berridge, 2015. "Joint modeling of mixed skewed continuous and ordinal longitudinal responses: a Bayesian approach," Journal of Applied Statistics, Taylor & Francis Journals, vol. 42(10), pages 2233-2256, October.
    5. Ye, Rendao & Wang, Tonghui & Gupta, Arjun K., 2014. "Distribution of matrix quadratic forms under skew-normal settings," Journal of Multivariate Analysis, Elsevier, vol. 131(C), pages 229-239.
    6. Lourdes Montenegro & Víctor Lachos & Heleno Bolfarine, 2010. "Inference for a skew extension of the Grubbs model," Statistical Papers, Springer, vol. 51(3), pages 701-715, September.
    7. F. Kahrari & C. S. Ferreira & R. B. Arellano-Valle, 2019. "Skew-Normal-Cauchy Linear Mixed Models," Sankhya B: The Indian Journal of Statistics, Springer;Indian Statistical Institute, vol. 81(2), pages 185-202, December.
    8. Kheradmandi, Ameneh & Rasekh, Abdolrahman, 2015. "Estimation in skew-normal linear mixed measurement error models," Journal of Multivariate Analysis, Elsevier, vol. 136(C), pages 1-11.
    9. Huang Yangxin & Chen Jiaqing & Yan Chunning, 2012. "Mixed-Effects Joint Models with Skew-Normal Distribution for HIV Dynamic Response with Missing and Mismeasured Time-Varying Covariate," The International Journal of Biostatistics, De Gruyter, vol. 8(1), pages 1-30, November.
    10. Reinaldo B. Arellano-Valle & Javier E. Contreras-Reyes & Freddy O. López Quintero & Abel Valdebenito, 2019. "A skew-normal dynamic linear model and Bayesian forecasting," Computational Statistics, Springer, vol. 34(3), pages 1055-1085, September.
    11. Yangxin Huang & Tao Lu, 2017. "Bayesian inference on partially linear mixed-effects joint models for longitudinal data with multiple features," Computational Statistics, Springer, vol. 32(1), pages 179-196, March.
    12. Philip S. Boonstra & Bhramar Mukherjee & Jeremy M. G. Taylor & Mef Nilbert & Victor Moreno & Stephen B. Gruber, 2011. "Bayesian Modeling for Genetic Anticipation in Presence of Mutational Heterogeneity: A Case Study in Lynch Syndrome," Biometrics, The International Biometric Society, vol. 67(4), pages 1627-1637, December.
    13. Huang, Pei & McCarl, Bruce A., 2014. "Estimating Decadal Climate Variability Effects on Crop Yields: A Bayesian Hierarchical Approach," 2014 Annual Meeting, July 27-29, 2014, Minneapolis, Minnesota 169828, Agricultural and Applied Economics Association.
    14. Zhongwei Zhang & Reinaldo B. Arellano‐Valle & Marc G. Genton & Raphaël Huser, 2023. "Tractable Bayes of skew‐elliptical link models for correlated binary data," Biometrics, The International Biometric Society, vol. 79(3), pages 1788-1800, September.
    15. Zeinolabedin Najafi & Karim Zare & Mohammad Reza Mahmoudi & Soheil Shokri & Amir Mosavi, 2022. "Inference and Local Influence Assessment in a Multifactor Skew-Normal Linear Mixed Model," Mathematics, MDPI, vol. 10(15), pages 1-21, August.
    16. Lin, Tsung I. & Ho, Hsiu J. & Chen, Chiang L., 2009. "Analysis of multivariate skew normal models with incomplete data," Journal of Multivariate Analysis, Elsevier, vol. 100(10), pages 2337-2351, November.
    17. Padilla, Juan L. & Azevedo, Caio L.N. & Lachos, Victor H., 2018. "Multidimensional multiple group IRT models with skew normal latent trait distributions," Journal of Multivariate Analysis, Elsevier, vol. 167(C), pages 250-268.
    18. Reinaldo B. Arellano-Valle & Marc G. Genton, 2010. "Multivariate extended skew-t distributions and related families," Metron - International Journal of Statistics, Dipartimento di Statistica, Probabilità e Statistiche Applicate - University of Rome, vol. 0(3), pages 201-234.
    19. Peng Zhang & Peter X.-K. Song & Annie Qu & Tom Greene, 2008. "Efficient Estimation for Patient-Specific Rates of Disease Progression Using Nonnormal Linear Mixed Models," Biometrics, The International Biometric Society, vol. 64(1), pages 29-38, March.
    20. Ali Genç, 2013. "A skew extension of the slash distribution via beta-normal distribution," Statistical Papers, Springer, vol. 54(2), pages 427-442, May.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:taf:japsta:v:39:y:2012:i:5:p:1087-1100. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Longhurst (email available below). General contact details of provider: http://www.tandfonline.com/CJAS20 .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.