IDEAS home Printed from https://ideas.repec.org/p/boc/usug19/02.html
   My bibliography  Save this paper

Developing a postestimation command for joint models in merlin

Author

Listed:
  • Nuzhat B. Ashra

    (Biostatistics Research Group, Department of Health Sciences, University of Leicester)

  • Michael Crowther

    (Biostatistics Research Group, Department of Health Sciences, University of Leicester)

Abstract

Joint longitudinal-survival models are now increasingly utilized to quantify the association between a repeatedly measured biomarker and time-to-event outcome. Where singular methods ignore the dependency between the biomarker and time-to-event outcome, joint models describe the association while accounting for possible measurement error and the intermittent nature of observations. Furthermore, extensions to these models can allow estimation of survival probabilities that are conditional on measurements to date and individual characteristic information. These probabilities give an up-to-date risk estimate for event occurrence tailored to the individual. Currently, there are two commands available in Stata, that are designed to fit these models. The command stjm was first on the scene and was specifically written to fit joint models. However, as the new kid on the block, merlin has greater flexibility than its predecessor. As a fairly recently established command, however, the postestimation command options are still a work in progress. The aim is to establish a command using both ado and Mata programming that will be able to produce a graphical illustration of individualized conditional survival probabilities. In this presentation, I will be talking about my coding journey to this end.

Suggested Citation

  • Nuzhat B. Ashra & Michael Crowther, 2019. "Developing a postestimation command for joint models in merlin," London Stata Conference 2019 02, Stata Users Group.
    • Handle: RePEc:boc:usug19:02
    as

    Download full text from publisher

    File URL: http://repec.org/usug2019/Ashra_uk19.pdf
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Dimitris Rizopoulos, 2011. "Dynamic Predictions and Prospective Accuracy in Joint Models for Longitudinal and Time-to-Event Data," Biometrics, The International Biometric Society, vol. 67(3), pages 819-829, September.
    2. Eleni†Rosalina Andrinopoulou & Paul H. C. Eilers & Johanna J. M. Takkenberg & Dimitris Rizopoulos, 2018. "Improved dynamic predictions from joint models of longitudinal and survival data with time†varying effects using P†splines," Biometrics, The International Biometric Society, vol. 74(2), pages 685-693, June.
    3. Michael J. Crowther & Keith R. Abrams & Paul C. Lambert, 2013. "Joint modeling of longitudinal and survival data," Stata Journal, StataCorp LP, vol. 13(1), pages 165-184, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Zhang, Zili & Charalambous, Christiana & Foster, Peter, 2023. "A Gaussian copula joint model for longitudinal and time-to-event data with random effects," Computational Statistics & Data Analysis, Elsevier, vol. 181(C).
    2. Wang, Shikun & Li, Zhao & Lan, Lan & Zhao, Jieyi & Zheng, W. Jim & Li, Liang, 2022. "GPU accelerated estimation of a shared random effect joint model for dynamic prediction," Computational Statistics & Data Analysis, Elsevier, vol. 174(C).
    3. Jahani, Salman & Zhou, Shiyu & Veeramani, Dharmaraj, 2021. "Stochastic prognostics under multiple time-varying environmental factors," Reliability Engineering and System Safety, Elsevier, vol. 215(C).
    4. Li, Kan & Luo, Sheng, 2019. "Bayesian functional joint models for multivariate longitudinal and time-to-event data," Computational Statistics & Data Analysis, Elsevier, vol. 129(C), pages 14-29.
    5. Marlena Maziarz & Patrick Heagerty & Tianxi Cai & Yingye Zheng, 2017. "On longitudinal prediction with time-to-event outcome: Comparison of modeling options," Biometrics, The International Biometric Society, vol. 73(1), pages 83-93, March.
    6. Rizopoulos, Dimitris, 2016. "The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data Using MCMC," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 72(i07).
    7. Eleni†Rosalina Andrinopoulou & Paul H. C. Eilers & Johanna J. M. Takkenberg & Dimitris Rizopoulos, 2018. "Improved dynamic predictions from joint models of longitudinal and survival data with time†varying effects using P†splines," Biometrics, The International Biometric Society, vol. 74(2), pages 685-693, June.
    8. Michael J. Crowther & Keith R. Abrams & Paul C. Lambert, 2013. "Joint modeling of longitudinal and survival data," Stata Journal, StataCorp LP, vol. 13(1), pages 165-184, March.
    9. Carles Serrat & Montserrat Ru� & Carmen Armero & Xavier Piulachs & H�ctor Perpi��n & Anabel Forte & �lvaro P�ez & Guadalupe G�mez, 2015. "Frequentist and Bayesian approaches for a joint model for prostate cancer risk and longitudinal prostate-specific antigen data," Journal of Applied Statistics, Taylor & Francis Journals, vol. 42(6), pages 1223-1239, June.
    10. Anirudh Tomer & Daan Nieboer & Monique J. Roobol & Ewout W. Steyerberg & Dimitris Rizopoulos, 2019. "Personalized schedules for surveillance of low‐risk prostate cancer patients," Biometrics, The International Biometric Society, vol. 75(1), pages 153-162, March.
    11. Dimitris Rizopoulos & Laura A. Hatfield & Bradley P. Carlin & Johanna J. M. Takkenberg, 2014. "Combining Dynamic Predictions From Joint Models for Longitudinal and Time-to-Event Data Using Bayesian Model Averaging," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 109(508), pages 1385-1397, December.
    12. Lisa M. McCrink & Adele H. Marshall & Karen J. Cairns, 2013. "Advances in Joint Modelling: A Review of Recent Developments with Application to the Survival of End Stage Renal Disease Patients," International Statistical Review, International Statistical Institute, vol. 81(2), pages 249-269, August.
    13. Qing Liu & Gong Tang & Joseph P. Costantino & Chung‐Chou H. Chang, 2020. "Landmark proportional subdistribution hazards models for dynamic prediction of cumulative incidence functions," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 69(5), pages 1145-1162, November.
    14. Janet Niekerk & Haakon Bakka & Håvard Rue, 2023. "Stable Non-Linear Generalized Bayesian Joint Models for Survival-Longitudinal Data," Sankhya A: The Indian Journal of Statistics, Springer;Indian Statistical Institute, vol. 85(1), pages 102-128, February.
    15. Paul Blanche & Cécile Proust-Lima & Lucie Loubère & Claudine Berr & Jean-François Dartigues & Hélène Jacqmin-Gadda, 2015. "Quantifying and comparing dynamic predictive accuracy of joint models for longitudinal marker and time-to-event in presence of censoring and competing risks," Biometrics, The International Biometric Society, vol. 71(1), pages 102-113, March.
    16. Philipson, Pete & Hickey, Graeme L. & Crowther, Michael J. & Kolamunnage-Dona, Ruwanthi, 2020. "Faster Monte Carlo estimation of joint models for time-to-event and multivariate longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 151(C).
    17. Kamaryn T. Tanner & Linda D. Sharples & Rhian M. Daniel & Ruth H. Keogh, 2021. "Dynamic survival prediction combining landmarking with a machine learning ensemble: Methodology and empirical comparison," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 184(1), pages 3-30, January.
    18. Zhang, Cuihong & Ning, Jing & Cai, Jianwen & Squires, James E. & Belle, Steven H. & Li, Ruosha, 2024. "Dynamic risk score modeling for multiple longitudinal risk factors and survival," Computational Statistics & Data Analysis, Elsevier, vol. 189(C).
    19. Syden Mishi & Weliswa Matekenya & Leward Jeke & Ronney M. Ncwadi & Roseline T. Karambakuwa, 2021. "Firm and product survival analysis: Evidence from South African tax administrative and products data," WIDER Working Paper Series wp-2021-107, World Institute for Development Economic Research (UNU-WIDER).
    20. Liang Li & Sheng Luo & Bo Hu & Tom Greene, 2017. "Dynamic Prediction of Renal Failure Using Longitudinal Biomarkers in a Cohort Study of Chronic Kidney Disease," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 9(2), pages 357-378, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:boc:usug19:02. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Christopher F Baum (email available below). General contact details of provider: https://edirc.repec.org/data/stataea.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.