IDEAS home Printed from https://ideas.repec.org/p/arx/papers/2403.01386.html
   My bibliography  Save this paper

Minimax-Regret Sample Selection in Randomized Experiments

Author

Listed:
  • Yuchen Hu
  • Henry Zhu
  • Emma Brunskill
  • Stefan Wager

Abstract

Randomized controlled trials are often run in settings with many subpopulations that may have differential benefits from the treatment being evaluated. We consider the problem of sample selection, i.e., whom to enroll in a randomized trial, such as to optimize welfare in a heterogeneous population. We formalize this problem within the minimax-regret framework, and derive optimal sample-selection schemes under a variety of conditions. Using data from a COVID-19 vaccine trial, we also highlight how different objectives and decision rules can lead to meaningfully different guidance regarding optimal sample allocation.

Suggested Citation

  • Yuchen Hu & Henry Zhu & Emma Brunskill & Stefan Wager, 2024. "Minimax-Regret Sample Selection in Randomized Experiments," Papers 2403.01386, arXiv.org, revised Jun 2024.
    • Handle: RePEc:arx:papers:2403.01386
    as

    Download full text from publisher

    File URL: http://arxiv.org/pdf/2403.01386
    File Function: Latest version
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Stoye, Jörg, 2009. "Minimax regret treatment choice with finite samples," Journal of Econometrics, Elsevier, vol. 151(1), pages 70-81, July.
    2. Keisuke Hirano & Jack R. Porter, 2009. "Asymptotics for Statistical Treatment Rules," Econometrica, Econometric Society, vol. 77(5), pages 1683-1701, September.
    3. Herve Moulin, 2004. "Fair Division and Collective Welfare," MIT Press Books, The MIT Press, edition 1, volume 1, number 0262633116, April.
    4. Toru Kitagawa & Aleksey Tetenov, 2018. "Who Should Be Treated? Empirical Welfare Maximization Methods for Treatment Choice," Econometrica, Econometric Society, vol. 86(2), pages 591-616, March.
    5. Charles F. Manski, 2004. "Statistical Treatment Rules for Heterogeneous Populations," Econometrica, Econometric Society, vol. 72(4), pages 1221-1246, July.
    6. Kaneko, Mamoru & Nakamura, Kenjiro, 1979. "The Nash Social Welfare Function," Econometrica, Econometric Society, vol. 47(2), pages 423-435, March.
    7. Susan Athey & Stefan Wager, 2021. "Policy Learning With Observational Data," Econometrica, Econometric Society, vol. 89(1), pages 133-161, January.
    8. Azevedo, Eduardo M. & Mao, David & Montiel Olea, José Luis & Velez, Amilcar, 2023. "The A/B testing problem with Gaussian priors," Journal of Economic Theory, Elsevier, vol. 210(C).
    9. Nathan Kallus, 2021. "On the optimality of randomization in experimental design: How to randomize for minimax variance and design‐based inference," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 83(2), pages 404-409, April.
    10. Imbens,Guido W. & Rubin,Donald B., 2015. "Causal Inference for Statistics, Social, and Biomedical Sciences," Cambridge Books, Cambridge University Press, number 9780521885881, October.
    11. Marcella Alsan & Maya Durvasula & Harsh Gupta & Joshua Schwartzstein & Heidi Williams, 2024. "Representation and Extrapolation: Evidence from Clinical Trials," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 139(1), pages 575-635.
    12. Eduardo M. Azevedo & Alex Deng & José Luis Montiel Olea & Justin Rao & E. Glen Weyl, 2020. "A/B Testing with Fat Tails," Journal of Political Economy, University of Chicago Press, vol. 128(12), pages 4614-4000.
    13. Stoye, Jörg, 2012. "Minimax regret treatment choice with covariates or with limited validity of experiments," Journal of Econometrics, Elsevier, vol. 166(1), pages 138-156.
    14. Charles F. Manski & Aleksey Tetenov, 2019. "Trial Size for Near-Optimal Choice Between Surveillance and Aggressive Treatment: Reconsidering MSLT-II," The American Statistician, Taylor & Francis Journals, vol. 73(S1), pages 305-311, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Manski, Charles F., 2023. "Probabilistic prediction for binary treatment choice: With focus on personalized medicine," Journal of Econometrics, Elsevier, vol. 234(2), pages 647-663.
    2. Charles F. Manski, 2021. "Econometrics for Decision Making: Building Foundations Sketched by Haavelmo and Wald," Econometrica, Econometric Society, vol. 89(6), pages 2827-2853, November.
    3. Yuehao Bai & Azeem M. Shaikh & Max Tabord-Meehan, 2024. "A Primer on the Analysis of Randomized Experiments and a Survey of some Recent Advances," Papers 2405.03910, arXiv.org.
    4. Kock, Anders Bredahl & Preinerstorfer, David & Veliyev, Bezirgen, 2023. "Treatment recommendation with distributional targets," Journal of Econometrics, Elsevier, vol. 234(2), pages 624-646.
    5. Susan Athey & Stefan Wager, 2021. "Policy Learning With Observational Data," Econometrica, Econometric Society, vol. 89(1), pages 133-161, January.
    6. Augustine Denteh & Helge Liebert, 2022. "Who Increases Emergency Department Use? New Insights from the Oregon Health Insurance Experiment," Papers 2201.07072, arXiv.org, revised Apr 2023.
    7. Kitagawa, Toru & Wang, Guanyi, 2023. "Who should get vaccinated? Individualized allocation of vaccines over SIR network," Journal of Econometrics, Elsevier, vol. 232(1), pages 109-131.
    8. Seungjin Han & Julius Owusu & Youngki Shin, 2022. "Statistical Treatment Rules under Social Interaction," Papers 2209.09077, arXiv.org, revised Nov 2022.
    9. Davide Viviano, 2019. "Policy Targeting under Network Interference," Papers 1906.10258, arXiv.org, revised Apr 2024.
    10. Toru Kitagawa & Sokbae Lee & Chen Qiu, 2022. "Treatment Choice with Nonlinear Regret," Papers 2205.08586, arXiv.org, revised Oct 2024.
    11. Eric Mbakop & Max Tabord‐Meehan, 2021. "Model Selection for Treatment Choice: Penalized Welfare Maximization," Econometrica, Econometric Society, vol. 89(2), pages 825-848, March.
    12. Garbero, Alessandra & Sakos, Grayson & Cerulli, Giovanni, 2023. "Towards data-driven project design: Providing optimal treatment rules for development projects," Socio-Economic Planning Sciences, Elsevier, vol. 89(C).
    13. Michael C Knaus, 2022. "Double machine learning-based programme evaluation under unconfoundedness [Econometric methods for program evaluation]," The Econometrics Journal, Royal Economic Society, vol. 25(3), pages 602-627.
    14. Azevedo, Eduardo M. & Mao, David & Montiel Olea, José Luis & Velez, Amilcar, 2023. "The A/B testing problem with Gaussian priors," Journal of Economic Theory, Elsevier, vol. 210(C).
    15. Shosei Sakaguchi, 2021. "Estimation of Optimal Dynamic Treatment Assignment Rules under Policy Constraints," Papers 2106.05031, arXiv.org, revised Aug 2024.
    16. Henrika Langen & Martin Huber, 2022. "How causal machine learning can leverage marketing strategies: Assessing and improving the performance of a coupon campaign," Papers 2204.10820, arXiv.org, revised Jun 2022.
    17. Keisuke Hirano & Jack R. Porter, 2016. "Panel Asymptotics and Statistical Decision Theory," The Japanese Economic Review, Japanese Economic Association, vol. 67(1), pages 33-49, March.
    18. Yu-Chang Chen & Haitian Xie, 2022. "Personalized Subsidy Rules," Papers 2202.13545, arXiv.org, revised Mar 2022.
    19. Thomas M. Russell, 2020. "Policy Transforms and Learning Optimal Policies," Papers 2012.11046, arXiv.org.
    20. Takanori Ida & Takunori Ishihara & Koichiro Ito & Daido Kido & Toru Kitagawa & Shosei Sakaguchi & Shusaku Sasaki, 2022. "Choosing Who Chooses: Selection-Driven Targeting in Energy Rebate Programs," NBER Working Papers 30469, National Bureau of Economic Research, Inc.

    More about this item

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:arx:papers:2403.01386. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: arXiv administrators (email available below). General contact details of provider: http://arxiv.org/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.