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Individual Preferences for Child and Adolescent Vaccine Attributes: A Systematic Review of the Stated Preference Literature

Author

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  • Christine Michaels-Igbokwe

    (University of Calgary)

  • Shannon MacDonald

    (University of Alberta
    University of Calgary)

  • Gillian R. Currie

    (University of Calgary)

Abstract

Background Discrete choice experiments are increasingly used to assess preferences for vaccines and vaccine service delivery. Objectives To synthesize and critically assess the application of discrete choice experiments in childhood/adolescent vaccines, to describe how discrete choice experiments have been applied to understand preferences, and to evaluate the use of discrete choice experiment data to inform estimates of vaccine uptake. Methods We conducted a systematic review of six electronic databases. Included studies were discrete choice experiments and conjoint analyses published from 2000 to 2016 related to childhood/adolescent vaccines where respondents were parents, children/adolescents, or service providers. Validity assessment was used to assess study quality and risk of bias. Results In total, 27 articles were included, representing 21 different studies. A majority of articles were published between 2011 and 2016. Vaccines studied included human papillomavirus (24%), influenza (19%), meningococcal vaccines (14%), childhood vaccines (14%), hypothetical vaccines (10%), hepatitis B (5%), and diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and Haemophilus influenzae type b (5%). Most studies assessed parent preferences (67%). The most common attributes were risk (24%), degree/duration of protection (21%), and cost (15%). Commonly reported outcome measures were estimates of uptake (33%), willingness-to-pay (22%), and other marginal rates of substitution (14%). Validity assessments yielded high scores overall. Areas of weakness included low response rates, inefficient experimental design, and failure to conduct formative qualitative work and a pilot of the discrete choice experiment. Conclusion This is the first systematic review of childhood/adolescent vaccine-related discrete choice experiments. In future, special attention should be paid to ensuring that choice context and discrete choice experiment design are compatible to generate reliable estimates of uptake.

Suggested Citation

  • Christine Michaels-Igbokwe & Shannon MacDonald & Gillian R. Currie, 2017. "Individual Preferences for Child and Adolescent Vaccine Attributes: A Systematic Review of the Stated Preference Literature," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 10(6), pages 687-700, December.
    • Handle: RePEc:spr:patien:v:10:y:2017:i:6:d:10.1007_s40271-017-0244-x
    DOI: 10.1007/s40271-017-0244-x
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    References listed on IDEAS

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    1. Hensher,David A. & Rose,John M. & Greene,William H., 2015. "Applied Choice Analysis," Cambridge Books, Cambridge University Press, number 9781107465923, October.
    2. Jane Hall & Patricia Kenny & Madeleine King & Jordan Louviere & Rosalie Viney & Angela Yeoh, 2002. "Using stated preference discrete choice modelling to evaluate the introduction of varicella vaccination," Health Economics, John Wiley & Sons, Ltd., vol. 11(5), pages 457-465, July.
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    Cited by:

    1. Minghuan Jiang & Yilin Gong & Yu Fang & Xuelin Yao & Liuxin Feng & Shan Zhu & Jin Peng & Xinke Shi, 2022. "Parental Preferences of Influenza Vaccination for Children in China: A National Survey with a Discrete Choice Experiment," IJERPH, MDPI, vol. 19(4), pages 1-14, February.
    2. Christine Michaels-Igbokwe & Gillian R. Currie & Bryanne L. Kennedy & Karen V. MacDonald & Deborah A. Marshall, 2021. "Methods for Conducting Stated Preference Research with Children and Adolescents in Health: A Scoping Review of the Application of Discrete Choice Experiments," The Patient: Patient-Centered Outcomes Research, Springer;International Academy of Health Preference Research, vol. 14(6), pages 741-758, November.
    3. William F. Vásquez & Jennifer M. Trudeau & Jessica Alicea‐Planas, 2021. "Immediate and informative feedback during a pandemic: Using stated preference analysis to predict vaccine uptake rates," Health Economics, John Wiley & Sons, Ltd., vol. 30(12), pages 3123-3137, December.
    4. Vikas Soekhai & Esther W. Bekker-Grob & Alan R. Ellis & Caroline M. Vass, 2019. "Discrete Choice Experiments in Health Economics: Past, Present and Future," PharmacoEconomics, Springer, vol. 37(2), pages 201-226, February.
    5. Luyten, Jeroen & Beutels, Philippe & Vandermeulen, Corinne & Kessels, Roselinde, 2022. "Social preferences for adopting new vaccines in the national immunization program: A discrete choice experiment," Social Science & Medicine, Elsevier, vol. 303(C).
    6. Gemma Lasseter & Hareth Al-Janabi & Caroline L Trotter & Fran E Carroll & Hannah Christensen, 2018. "The views of the general public on prioritising vaccination programmes against childhood diseases: A qualitative study," PLOS ONE, Public Library of Science, vol. 13(6), pages 1-18, June.

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