IDEAS home Printed from https://ideas.repec.org/a/spr/lifeda/v27y2021i1d10.1007_s10985-020-09507-z.html
   My bibliography  Save this article

EM algorithm for the additive risk mixture cure model with interval-censored data

Author

Listed:
  • Xiaoguang Wang

    (Dalian University of Technology)

  • Ziwen Wang

    (Dalian University of Technology)

Abstract

Interval-censored failure time data arise in a number of fields and many authors have recently paid more attention to their analysis. However, regression analysis of interval-censored data under the additive risk model can be challenging in maximizing the complex likelihood, especially when there exists a non-ignorable cure fraction in the population. For the problem, we develop a sieve maximum likelihood estimation approach based on Bernstein polynomials. To relieve the computational burden, an expectation–maximization algorithm by exploiting a Poisson data augmentation is proposed. Under some mild conditions, the asymptotic properties of the proposed estimator are established. The finite sample performance of the proposed method is evaluated by extensive simulations, and is further illustrated through a real data set from the smoking cessation study.

Suggested Citation

  • Xiaoguang Wang & Ziwen Wang, 2021. "EM algorithm for the additive risk mixture cure model with interval-censored data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(1), pages 91-130, January.
    • Handle: RePEc:spr:lifeda:v:27:y:2021:i:1:d:10.1007_s10985-020-09507-z
    DOI: 10.1007/s10985-020-09507-z
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s10985-020-09507-z
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s10985-020-09507-z?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. D. Ghosh, 2001. "Efficiency Considerations in the Additive Hazards Model with Current Status Data," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 55(3), pages 367-376, November.
    2. Yu Shen & S. C. Cheng, 1999. "Confidence Bands for Cumulative Incidence Curves Under the Additive Risk Model," Biometrics, The International Biometric Society, vol. 55(4), pages 1093-1100, December.
    3. Sudipto Banerjee & Bradley P. Carlin, 2004. "Parametric Spatial Cure Rate Models for Interval-Censored Time-to-Relapse Data," Biometrics, The International Biometric Society, vol. 60(1), pages 268-275, March.
    4. Hu, Tao & Xiang, Liming, 2013. "Efficient estimation for semiparametric cure models with interval-censored data," Journal of Multivariate Analysis, Elsevier, vol. 121(C), pages 139-151.
    5. Liu, Hao & Shen, Yu, 2009. "A Semiparametric Regression Cure Model for Interval-Censored Data," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1168-1178.
    6. Yingwei Peng & Keith B. G. Dear, 2000. "A Nonparametric Mixture Model for Cure Rate Estimation," Biometrics, The International Biometric Society, vol. 56(1), pages 237-243, March.
    7. Hu, Tao & Xiang, Liming, 2016. "Partially linear transformation cure models for interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 257-269.
    8. Torben Martinussen, 2002. "Efficient estimation in additive hazards regression with current status data," Biometrika, Biometrika Trust, vol. 89(3), pages 649-658, August.
    9. Yeqian Liu & Tao Hu & Jianguo Sun, 2017. "Regression analysis of current status data in the presence of a cured subgroup and dependent censoring," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 23(4), pages 626-650, October.
    10. Judy P. Sy & Jeremy M. G. Taylor, 2000. "Estimation in a Cox Proportional Hazards Cure Model," Biometrics, The International Biometric Society, vol. 56(1), pages 227-236, March.
    11. Li, Chin-Shang & Taylor, Jeremy M. G. & Sy, Judy P., 2001. "Identifiability of cure models," Statistics & Probability Letters, Elsevier, vol. 54(4), pages 389-395, October.
    12. Yuan Wu & Christina D. Chambers & Ronghui Xu, 2019. "Semiparametric sieve maximum likelihood estimation under cure model with partly interval censored and left truncated data for application to spontaneous abortion," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(3), pages 507-528, July.
    13. Shuangge Ma, 2011. "Additive risk model for current status data with a cured subgroup," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 63(1), pages 117-134, February.
    14. Hanin, Leonid & Huang, Li-Shan, 2014. "Identifiability of cure models revisited," Journal of Multivariate Analysis, Elsevier, vol. 130(C), pages 261-274.
    15. Mao, Meng & Wang, Jane-Ling, 2010. "Semiparametric Efficient Estimation for a Class of Generalized Proportional Odds Cure Models," Journal of the American Statistical Association, American Statistical Association, vol. 105(489), pages 302-311.
    16. Osman, Muhtarjan & Ghosh, Sujit K., 2012. "Nonparametric regression models for right-censored data using Bernstein polynomials," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 559-573.
    17. Ying Zhang & Lei Hua & Jian Huang, 2010. "A Spline‐Based Semiparametric Maximum Likelihood Estimation Method for the Cox Model with Interval‐Censored Data," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 37(2), pages 338-354, June.
    18. Lianming Wang & Christopher S. McMahan & Michael G. Hudgens & Zaina P. Qureshi, 2016. "A flexible, computationally efficient method for fitting the proportional hazards model to interval-censored data," Biometrics, The International Biometric Society, vol. 72(1), pages 222-231, March.
    19. Yu, Binbing & Peng, Yingwei, 2008. "Mixture cure models for multivariate survival data," Computational Statistics & Data Analysis, Elsevier, vol. 52(3), pages 1524-1532, January.
    20. Xue H. & Lam K.F. & Li G., 2004. "Sieve Maximum Likelihood Estimator for Semiparametric Regression Models With Current Status Data," Journal of the American Statistical Association, American Statistical Association, vol. 99, pages 346-356, January.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Hu, Tao & Xiang, Liming, 2013. "Efficient estimation for semiparametric cure models with interval-censored data," Journal of Multivariate Analysis, Elsevier, vol. 121(C), pages 139-151.
    2. Hu, Tao & Xiang, Liming, 2016. "Partially linear transformation cure models for interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 257-269.
    3. Li, Shuwei & Hu, Tao & Zhao, Xingqiu & Sun, Jianguo, 2019. "A class of semiparametric transformation cure models for interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 133(C), pages 153-165.
    4. Frederico Machado Almeida & Enrico Antônio Colosimo & Vinícius Diniz Mayrink, 2021. "Firth adjusted score function for monotone likelihood in the mixture cure fraction model," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 27(1), pages 131-155, January.
    5. Liu, Xiaoyu & Xiang, Liming, 2021. "Generalized accelerated hazards mixture cure models with interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 161(C).
    6. Guoqing Diao & Ao Yuan, 2019. "A class of semiparametric cure models with current status data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(1), pages 26-51, January.
    7. Shuangge Ma, 2011. "Additive risk model for current status data with a cured subgroup," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 63(1), pages 117-134, February.
    8. Yuan Wu & Christina D. Chambers & Ronghui Xu, 2019. "Semiparametric sieve maximum likelihood estimation under cure model with partly interval censored and left truncated data for application to spontaneous abortion," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(3), pages 507-528, July.
    9. N. Balakrishnan & M. V. Koutras & F. S. Milienos & S. Pal, 2016. "Piecewise Linear Approximations for Cure Rate Models and Associated Inferential Issues," Methodology and Computing in Applied Probability, Springer, vol. 18(4), pages 937-966, December.
    10. Xu, Yang & Zhao, Shishun & Hu, Tao & Sun, Jianguo, 2021. "Variable selection for generalized odds rate mixture cure models with interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 156(C).
    11. Chen, Chyong-Mei & Lu, Tai-Fang C., 2012. "Marginal analysis of multivariate failure time data with a surviving fraction based on semiparametric transformation cure models," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 645-655.
    12. Han, Bo & Wang, Xiaoguang, 2020. "Semiparametric estimation for the non-mixture cure model in case-cohort and nested case-control studies," Computational Statistics & Data Analysis, Elsevier, vol. 144(C).
    13. Niu, Yi & Peng, Yingwei, 2014. "Marginal regression analysis of clustered failure time data with a cure fraction," Journal of Multivariate Analysis, Elsevier, vol. 123(C), pages 129-142.
    14. Hanin, Leonid & Huang, Li-Shan, 2014. "Identifiability of cure models revisited," Journal of Multivariate Analysis, Elsevier, vol. 130(C), pages 261-274.
    15. Ana López-Cheda & Yingwei Peng & María Amalia Jácome, 2023. "Nonparametric estimation in mixture cure models with covariates," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 32(2), pages 467-495, June.
    16. Bremhorst, Vincent & Lambert, Philippe, 2016. "Flexible estimation in cure survival models using Bayesian P-splines," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 270-284.
    17. López-Cheda, Ana & Cao, Ricardo & Jácome, M. Amalia & Van Keilegom, Ingrid, 2017. "Nonparametric incidence estimation and bootstrap bandwidth selection in mixture cure models," Computational Statistics & Data Analysis, Elsevier, vol. 105(C), pages 144-165.
    18. Li, Jinqing & Ma, Jun, 2019. "Maximum penalized likelihood estimation of additive hazards models with partly interval censoring," Computational Statistics & Data Analysis, Elsevier, vol. 137(C), pages 170-180.
    19. Zhiguo Li & Kouros Owzar, 2016. "Fitting Cox Models with Doubly Censored Data Using Spline-Based Sieve Marginal Likelihood," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 43(2), pages 476-486, June.
    20. Baihua He & Yanyan Liu & Yuanshan Wu & Xingqiu Zhao, 2020. "Semiparametric efficient estimation for additive hazards regression with case II interval-censored survival data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(4), pages 708-730, October.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:lifeda:v:27:y:2021:i:1:d:10.1007_s10985-020-09507-z. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.