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Socio-economic determinants of Chronic Kidney Diseases of uncertain etiology (CKDu) in the Uva Province, Sri Lanka: a cross-sectional study

Author

Listed:
  • I. D. U. H. Piyathilake

    (Sabaragamuwa University of Sri Lanka)

  • J. L. P. C. Randika

    (Sabaragamuwa University of Sri Lanka)

  • R. M. K. T. Rathnayaka

    (Sabaragamuwa University of Sri Lanka)

  • E. P. N. Udayakumara

    (Sabaragamuwa University of Sri Lanka)

  • L. V. Ranaweera

    (Sabaragamuwa University of Sri Lanka)

  • S. K. Gunatilake

    (Sabaragamuwa University of Sri Lanka)

  • C. B. Dissanayake

    (University of Peradeniya)

Abstract

CKDu is one of the most serious health problems in Sri Lanka. The country’s Uva Province (UP) faces an increasing number of CKDu patients. Therefore, this study develops a statistical model to identify the socio-economic determinants of CKDu in UP, Sri Lanka. This cross-sectional study draws on a questionnaire survey conducted with 229 farmers, of which 24% were CKDu patients, to ascertain the socio-economic predictors that contribute to CKDu. The relationship between socio-economic risk factors and CKDu was delineated using a logistic regression model and by analyzing odds ratios. The highest risk of CKDu was observed among participants who consume agrochemical-applied foods (OR 7.9657, 95% CI = 2.2205, 28.5755) and potentially contaminated drinking water (OR 3.3693, 95% CI = 1.5540, 7.3053). Furthermore, age (OR 1.1097 95% CI = 1.0542, 1.1680), gender (OR 4.4980, 95% CI = 1.1406, 17.7382), and education level (OR 21.1018, 95% CI = 1.7753, 250.8250) were also identified as significant risk factors.

Suggested Citation

  • I. D. U. H. Piyathilake & J. L. P. C. Randika & R. M. K. T. Rathnayaka & E. P. N. Udayakumara & L. V. Ranaweera & S. K. Gunatilake & C. B. Dissanayake, 2022. "Socio-economic determinants of Chronic Kidney Diseases of uncertain etiology (CKDu) in the Uva Province, Sri Lanka: a cross-sectional study," Journal of Environmental Studies and Sciences, Springer;Association of Environmental Studies and Sciences, vol. 12(4), pages 782-793, December.
    • Handle: RePEc:spr:jenvss:v:12:y:2022:i:4:d:10.1007_s13412-022-00780-y
    DOI: 10.1007/s13412-022-00780-y
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    References listed on IDEAS

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    1. Noble, Andrew, 2014. "Review of literature on chronic kidney disease of unknown etiology (CKDu) in Sri Lanka," IWMI Working Papers H046435, International Water Management Institute.
    2. Channa Jayasumana & Sarath Gunatilake & Priyantha Senanayake, 2014. "Glyphosate, Hard Water and Nephrotoxic Metals: Are They the Culprits Behind the Epidemic of Chronic Kidney Disease of Unknown Etiology in Sri Lanka?," IJERPH, MDPI, vol. 11(2), pages 1-23, February.
    3. Hansani Madushika Abeywickrama & Swarna Wimalasiri & Yu Koyama & Mieko Uchiyama & Utako Shimizu & Nahoko Kakihara & Rohana Chandrajith & Nishantha Nanayakkara, 2020. "Quality of Life and Symptom Burden among Chronic Kidney Disease of Uncertain Etiology (CKDu) Patients in Girandurukotte, Sri Lanka," IJERPH, MDPI, vol. 17(11), pages 1-16, June.
    4. Laila Fitria & Nurhayati Adnan Prihartono & Doni Hikmat Ramdhan & Tri Yunis Miko Wahyono & Pornpimol Kongtip & Susan Woskie, 2020. "Environmental and Occupational Risk Factors Associated with Chronic Kidney Disease of Unknown Etiology in West Javanese Rice Farmers, Indonesia," IJERPH, MDPI, vol. 17(12), pages 1-14, June.
    5. Titus Cooray & Yuansong Wei & Hui Zhong & Libing Zheng & Sujithra K. Weragoda & Rohan Weerasooriya, 2019. "Assessment of Groundwater Quality in CKDu Affected Areas of Sri Lanka: Implications for Drinking Water Treatment," IJERPH, MDPI, vol. 16(10), pages 1-16, May.
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