IDEAS home Printed from https://ideas.repec.org/a/spr/eujhec/v24y2023i3d10.1007_s10198-022-01478-2.html
   My bibliography  Save this article

A systematic review of the cost-effectiveness of renal replacement therapies, and consequences for decision-making in the end-stage renal disease treatment pathway

Author

Listed:
  • Ellen Busink

    (Fresenius Medical Care)

  • Dana Kendzia

    (Fresenius Medical Care)

  • Fatih Kircelli

    (Fresenius Medical Care)

  • Sophie Boeger

    (Fresenius Medical Care)

  • Jovana Petrovic

    (Fresenius Medical Care)

  • Helen Smethurst

    (Mtech Access Ltd)

  • Stephen Mitchell

    (Mtech Access Ltd)

  • Christian Apel

    (Fresenius Medical Care)

Abstract

Objectives Comparative economic assessments of renal replacement therapies (RRT) are common and often used to inform national policy in the management of end-stage renal disease (ESRD). This study aimed to assess existing cost-effectiveness analyses of dialysis modalities and consider whether the methods applied and results obtained reflect the complexities of the real-world treatment pathway experienced by ESRD patients. Methods A systematic literature review (SLR) was conducted to identify cost-effectiveness studies of dialysis modalities from 2005 onward by searching Embase, MEDLINE, EBM reviews, and EconLit. Economic evaluations were included if they compared distinct dialysis modalities (e.g. in-centre haemodialysis [ICHD], home haemodialysis [HHD] and peritoneal dialysis [PD]). Results In total, 19 cost-effectiveness studies were identified. There was considerable heterogeneity in perspectives, time horizon, discounting, utility values, sources of clinical and economic data, and extent of clinical and economic elements included. The vast majority of studies included an incident dialysis patient population. All studies concluded that home dialysis treatment options were cost-effective interventions. Conclusions Despite similar findings across studies, there are a number of uncertainties about which dialysis modalities represent the most cost-effective options for patients at different points in the care pathway. Most studies included an incident patient cohort; however, in clinical practice, patients may switch between different treatment modalities over time according to their clinical need and personal circumstances. Promoting health policies through financial incentives in renal care should reflect the cost-effectiveness of a comprehensive approach that considers different RRTs along the patient pathway; however, no such evidence is currently available.

Suggested Citation

  • Ellen Busink & Dana Kendzia & Fatih Kircelli & Sophie Boeger & Jovana Petrovic & Helen Smethurst & Stephen Mitchell & Christian Apel, 2023. "A systematic review of the cost-effectiveness of renal replacement therapies, and consequences for decision-making in the end-stage renal disease treatment pathway," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(3), pages 377-392, April.
    • Handle: RePEc:spr:eujhec:v:24:y:2023:i:3:d:10.1007_s10198-022-01478-2
    DOI: 10.1007/s10198-022-01478-2
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s10198-022-01478-2
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s10198-022-01478-2?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Naren Kumar Surendra & Mohd Rizal Abdul Manaf & Lai Seong Hooi & Sunita Bavanandan & Fariz Safhan Mohamad Nor & Shahnaz Shah Firdaus Khan & Ong Loke Meng & Abdul Halim Abdul Gafor, 2019. "Cost utility analysis of end stage renal disease treatment in Ministry of Health dialysis centres, Malaysia: Hemodialysis versus continuous ambulatory peritoneal dialysis," PLOS ONE, Public Library of Science, vol. 14(10), pages 1-16, October.
    2. Catrin Treharne & Frank Liu & Murat Arici & Lydia Crowe & Usman Farooqui, 2014. "Peritoneal Dialysis and In-Centre Haemodialysis: A Cost-Utility Analysis from a UK Payer Perspective," Applied Health Economics and Health Policy, Springer, vol. 12(4), pages 409-420, August.
    3. Kontodimopoulos, Nick & Niakas, Dimitris, 2008. "An estimate of lifelong costs and QALYs in renal replacement therapy based on patients' life expectancy," Health Policy, Elsevier, vol. 86(1), pages 85-96, April.
    4. Matthew J Page & Joanne E McKenzie & Patrick M Bossuyt & Isabelle Boutron & Tammy C Hoffmann & Cynthia D Mulrow & Larissa Shamseer & Jennifer M Tetzlaff & Elie A Akl & Sue E Brennan & Roger Chou & Jul, 2021. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-15, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Boglárka Anna Éliás & Attila Jámbor, 2021. "Food Security and COVID-19: A Systematic Review of the First-Year Experience," Sustainability, MDPI, vol. 13(9), pages 1-18, May.
    2. Omoyele, Olalekan & Hoffmann, Maximilian & Koivisto, Matti & Larrañeta, Miguel & Weinand, Jann Michael & Linßen, Jochen & Stolten, Detlef, 2024. "Increasing the resolution of solar and wind time series for energy system modeling: A review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 189(PB).
    3. Cala, Anggie & Maturana-Córdoba, Aymer & Soto-Verjel, Joseph, 2023. "Exploring the pretreatments' influence on pressure reverse osmosis: PRISMA review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 188(C).
    4. Ming Shan & Yu-Shan Li & Bon-Gang Hwang & Jia-En Chua, 2021. "Productivity Metrics and Its Implementations in Construction Projects: A Case Study of Singapore," Sustainability, MDPI, vol. 13(21), pages 1-19, November.
    5. Susca, T. & Zanghirella, F. & Colasuonno, L. & Del Fatto, V., 2022. "Effect of green wall installation on urban heat island and building energy use: A climate-informed systematic literature review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 159(C).
    6. Alexander P. L. Martindale & Carrie D. Llewellyn & Richard O. Visser & Benjamin Ng & Victoria Ngai & Aditya U. Kale & Lavinia Ferrante Ruffano & Robert M. Golub & Gary S. Collins & David Moher & Melis, 2024. "Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    7. Gizéh Rangel-de Lázaro & Josep M. Duart, 2023. "You Can Handle, You Can Teach It: Systematic Review on the Use of Extended Reality and Artificial Intelligence Technologies for Online Higher Education," Sustainability, MDPI, vol. 15(4), pages 1-23, February.
    8. Kim, Hyunil & Kim, Yun Young & Song, Eun-Jee & Windsor, Liliane, 2024. "Policies to reduce child poverty and child maltreatment: A scoping review and preliminary estimates of indirect effects," Children and Youth Services Review, Elsevier, vol. 156(C).
    9. Lee, Kuan-Ting & Chen, Yen-Chin & Yang, Yi-Ching & Wang, Wei-Li, 2024. "On practicing magicine, from wonder to care: A systematic review of studies that apply magic in healthcare," Social Science & Medicine, Elsevier, vol. 341(C).
    10. Deniz Dutz & Ingrid Huitfeldt & Santiago Lacouture & Magne Mogstad & Alexander Torgovitsky & Winnie van Dijk, 2021. "Selection in Surveys," NBER Working Papers 29549, National Bureau of Economic Research, Inc.
      • Deniz Dutz & Ingrid Huitfeldt & Santiago Lacouture & Magne Mogstad & Alexander Torgovitsky & Winnie van Dijk, 2021. "Selection in Surveys," Discussion Papers 971, Statistics Norway, Research Department.
    11. Wang, Nan & Wang, Julian & Feng, Yanxiao, 2022. "Systematic review: Acute thermal effects of artificial light in the daytime," Renewable and Sustainable Energy Reviews, Elsevier, vol. 165(C).
    12. Tania Mateos-Blanco & Encarnación Sánchez‐Lissen & Inés Gil‐Jaurena & Clara Romero‐Pérez, 2022. "Child‐Led Participation: A Scoping Review of Empirical Studies," Social Inclusion, Cogitatio Press, vol. 10(2), pages 32-42.
    13. O'Donnell, Aisling T. & Foran, Aoife-Marie, 2024. "The link between anticipated and internalized stigma and depression: A systematic review," Social Science & Medicine, Elsevier, vol. 349(C).
    14. Fosch-Villaronga, Eduard & Calleja, Carlos José & Drukarch, Hadassah & Torricelli, Diego, 2023. "How can ISO 13482:2014 account for the ethical and social considerations of robotic exoskeletons?," Technology in Society, Elsevier, vol. 75(C).
    15. Elisa Mancinelli & Giulia Bassi & Silvia Gabrielli & Silvia Salcuni, 2022. "The Efficacy of Digital Cognitive–Behavioral Interventions in Supporting the Psychological Adjustment and Sleep Quality of Pregnant Women with Sub-Clinical Symptoms: A Systematic Review and Meta-Analy," IJERPH, MDPI, vol. 19(15), pages 1-18, August.
    16. Najihah Ahmad Latif & Fatini Nadhirah Mohd Nain & Nurul Hashimah Ahamed Hassain Malim & Rosni Abdullah & Muhammad Farid Abdul Rahim & Mohd Nasruddin Mohamad & Nurul Syafika Mohamad Fauzi, 2021. "Predicting Heritability of Oil Palm Breeding Using Phenotypic Traits and Machine Learning," Sustainability, MDPI, vol. 13(22), pages 1-24, November.
    17. Thøgersen, John, 2023. "How does origin labelling on food packaging influence consumer product evaluation and choices? A systematic literature review," Food Policy, Elsevier, vol. 119(C).
    18. Bei, Eva & Morrison, Val & Zarzycki, Mikołaj & Vilchinsky, Noa, 2023. "Barriers, facilitators, and motives to provide distance care, and the consequences for distance caregivers: A mixed-methods systematic review," Social Science & Medicine, Elsevier, vol. 321(C).
    19. Jacinda K. Dariotis & Frances R. Chen & Ye Rang Park & Montana K. Nowak & Katherine M. French & Anisa M. Codamon, 2023. "Parentification Vulnerability, Reactivity, Resilience, and Thriving: A Mixed Methods Systematic Literature Review," IJERPH, MDPI, vol. 20(13), pages 1-66, June.
    20. Lippens, Louis & Vermeiren, Siel & Baert, Stijn, 2023. "The state of hiring discrimination: A meta-analysis of (almost) all recent correspondence experiments," European Economic Review, Elsevier, vol. 151(C).

    More about this item

    Keywords

    Systematic review; Renal replacement therapy; Patient pathway management; Patient choice; Economic evaluation; Healthcare policy;
    All these keywords.

    JEL classification:

    • I11 - Health, Education, and Welfare - - Health - - - Analysis of Health Care Markets
    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:eujhec:v:24:y:2023:i:3:d:10.1007_s10198-022-01478-2. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.