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Prescribing Patterns of Codeine and Alternative Medicines in Children in Europe

Author

Listed:
  • Kelly Plueschke

    (European Medicines Agency)

  • Robert Flynn

    (European Medicines Agency
    University of Dundee)

  • Karin Hedenmalm

    (European Medicines Agency)

  • Aikaterini-Christina Deli

    (European Medicines Agency)

  • Miguel-Angel Maciá-Martinez

    (Agencia Española de Medicamentos y Productos Sanitarios)

  • Patricia García-Poza

    (Agencia Española de Medicamentos y Productos Sanitarios)

  • David Olsen

    (Norwegian Medicines Agency (Legemiddelverket))

  • Pierre Nguyen

    (French National Health Insurance (CNAM))

  • Chantal Quinten

    (European Medicines Agency)

Abstract

Introduction Concerns over serious respiratory depression in children led to two European Union (EU) referral procedures (in 2013 and 2015) to review the benefit–risk balance of codeine in this population when used for pain relief, cough or cold. Consequently, codeine should no longer be used in children aged

Suggested Citation

  • Kelly Plueschke & Robert Flynn & Karin Hedenmalm & Aikaterini-Christina Deli & Miguel-Angel Maciá-Martinez & Patricia García-Poza & David Olsen & Pierre Nguyen & Chantal Quinten, 2022. "Prescribing Patterns of Codeine and Alternative Medicines in Children in Europe," Drug Safety, Springer, vol. 45(10), pages 1069-1081, October.
    • Handle: RePEc:spr:drugsa:v:45:y:2022:i:10:d:10.1007_s40264-022-01214-y
    DOI: 10.1007/s40264-022-01214-y
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    References listed on IDEAS

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    1. Ariel Linden, 2015. "Conducting interrupted time-series analysis for single- and multiple-group comparisons," Stata Journal, StataCorp LP, vol. 15(2), pages 480-500, June.
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