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The Pharma-biotech Complex and Interconnected Regional Innovation Arenas

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  • Christian Zeller

    (Department of Geography and Geology, University of Salzburg, Hellbrunnerstrasse 34, A-5020 Salzburg, Austria, christian.zeller@sbg.ac.at)

Abstract

Large pharmaceutical firms, biotechnology firms, publicly funded research organisations and financial organisations which are inseparably connected and located in a few key regions have built a hierarchical pharma-biotech complex. It is argued that large corporations establish networks to access regionally concentrated knowledge bases. These networks consist of money flows, knowledge and personnel. By establishing such networks, large firms considerably shape and interconnect the development dynamics in the regions in which they have strategic assets. The paper reveals how the economic development trajectories of the urban regions of Basel, New Jersey and Boston are connected by large pharmaceutical firms and the industrial dynamics of the combined pharmaceutical and biotechnology industries. Such strong corporate networks result in the globally combined and interdependent development of urban regions.

Suggested Citation

  • Christian Zeller, 2010. "The Pharma-biotech Complex and Interconnected Regional Innovation Arenas," Urban Studies, Urban Studies Journal Limited, vol. 47(13), pages 2867-2894, November.
    • Handle: RePEc:sae:urbstu:v:47:y:2010:i:13:p:2867-2894
    DOI: 10.1177/0042098010377370
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    References listed on IDEAS

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    1. Feldman, Maryann & Schreuder, Yda, 1996. "Initial Advantage: The Origins of the Geographic Concentration of the Pharmaceutical Industry in the Mid-Atlantic Region," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 5(3), pages 839-862.
    2. Walter Powell & Kenneth Koput & James Bowie & Laurel Smith-Doerr, 2002. "The Spatial Clustering of Science and Capital: Accounting for Biotech Firm-Venture Capital Relationships," Regional Studies, Taylor & Francis Journals, vol. 36(3), pages 291-305.
    3. Claude Serfati, 2008. "Financial dimensions of transnational corporations, global value chain and technological innovation," Journal of Innovation Economics, De Boeck Université, vol. 0(2), pages 35-61.
    4. Sharmistha Bagchi-Sen & Helen Lawton Smith & Linda Hall, 2004. "The US Biotechnology Industry: Industry Dynamics and Policy," Environment and Planning C, , vol. 22(2), pages 199-216, April.
    5. Ashish Arora & Robert P. Merges, 2004. "Specialized supply firms, property rights and firm boundaries," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 13(3), pages 451-475, June.
    6. repec:dau:papers:123456789/2020 is not listed on IDEAS
    7. Christian Zeller, 2004. "North Atlantic Innovative Relations of Swiss Pharmaceuticals and the Proximities with Regional Biotech Arenas," Economic Geography, Taylor & Francis Journals, vol. 80(1), pages 83-111, January.
    8. Susan Christopherson & Jennifer Clark, 2007. "Power in Firm Networks: What it Means for Regional Innovation Systems," Regional Studies, Taylor & Francis Journals, vol. 41(9), pages 1223-1236.
    9. Mowery,David C. & Nelson,Richard R. (ed.), 1999. "Sources of Industrial Leadership," Cambridge Books, Cambridge University Press, number 9780521645201, January.
    10. M Gray & E Parker, 1998. "Industrial Change and Regional Development: The Case of the US Biotechnology and Pharmaceutical Industries," Environment and Planning A, , vol. 30(10), pages 1757-1774, October.
    11. Andy Pike, 2006. "'Shareholder value' versus the regions: the closure of the Vaux Brewery in Sunderland," Journal of Economic Geography, Oxford University Press, vol. 6(2), pages 201-222, April.
    12. Y Schreuder, 1998. "The German-American Pharmaceutical Business Establishment in the New York Metropolitan Region," Environment and Planning A, , vol. 30(10), pages 1743-1756, October.
    13. Kean Birch, 2008. "Alliance-Driven Governance: Applying a Global Commodity Chains Approach to the U.K. Biotechnology Industry," Economic Geography, Taylor & Francis Journals, vol. 84(1), pages 83-103, January.
    14. Cooke, Phil, 2005. "Regionally asymmetric knowledge capabilities and open innovation: Exploring 'Globalisation 2'--A new model of industry organisation," Research Policy, Elsevier, vol. 34(8), pages 1128-1149, October.
    15. Gassmann, Oliver & von Zedtwitz, Maximilian, 1999. "New concepts and trends in international R&D organization," Research Policy, Elsevier, vol. 28(2-3), pages 231-250, March.
    16. Swann, G. M. Peter & Prevezer, Martha & Stout, David (ed.), 1998. "The Dynamics of Industrial Clustering: International Comparisons in Computing and Biotechnology," OUP Catalogue, Oxford University Press, number 9780198289593.
    17. Gambardella,Alfonso, 1995. "Science and Innovation," Cambridge Books, Cambridge University Press, number 9780521451185, January.
    18. Christian Zeller, 2002. "Project Teams as Means of Restructuring Research and Development in the Pharmaceutical Industry," Regional Studies, Taylor & Francis Journals, vol. 36(3), pages 275-289.
    19. Edward L. Glaeser, 2005. "Reinventing Boston: 1630--2003," Journal of Economic Geography, Oxford University Press, vol. 5(2), pages 119-153, April.
    20. Jason Owen-Smith & Walter W. Powell, 2004. "Knowledge Networks as Channels and Conduits: The Effects of Spillovers in the Boston Biotechnology Community," Organization Science, INFORMS, vol. 15(1), pages 5-21, February.
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    2. Guido Capaldo & Margarida Fontes & Lorella Cannavacciuolo & Pierluigi Rippa & Cristina Sousa, 2015. "Networks Mobilized to Access Key Resources at Early Stages of Biotech Firms: A Comparative Analysis in Two Moderately Innovative Countries," European Planning Studies, Taylor & Francis Journals, vol. 23(7), pages 1381-1400, July.
    3. Chenxi Liu & Zhenghong Peng & Lingbo Liu & Shixuan Li, 2023. "Innovation Networks of Science and Technology Firms: Evidence from China," Land, MDPI, vol. 12(7), pages 1-21, June.
    4. Stefan Krätke, 2014. "Global Pharmaceutical and Biotechnology Firms’ Linkages in the World City Network," Urban Studies, Urban Studies Journal Limited, vol. 51(6), pages 1196-1213, May.
    5. Evgeniya Lupova-Henry & Sam Blili & Cinzia Dal Zotto, 2021. "Clusters as institutional entrepreneurs: lessons from Russia," Journal of Innovation and Entrepreneurship, Springer, vol. 10(1), pages 1-27, December.

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