IDEAS home Printed from https://ideas.repec.org/a/bla/tvecsg/v100y2009i3p332-347.html
   My bibliography  Save this article

The Economic Geography Of Knowledge Flow Hierarchies Among Internationally Networked Medical Bioclusters: A Scientometric Analysis

Author

Listed:
  • PHILIP COOKE

Abstract

This paper builds on a suite of research studies examining the metamorphosis in industry organisation, as Penrose calls it, regarding the centrality of firm capabilities in biosciences. Whereas knowledge leadership capabilities used to be inside global corporations now they have given way to university laboratories and dedicated biotechnology firm networks to access innovative research. The basic argument is that research centre and small firm knowledge capabilities have generally outstripped those of the multinationals in knowledge‐intensive industry, a consequence of which is a re‐alignment in cause‐and‐effect outcomes shaping economic geography. This is particularly pronounced in biosciences and pharmaceuticals. The paper mobilises a new theoretical framework and new data that support the thesis that a realignment of industry organisation around knowledge capabilities was pioneered in biosciences, is active in other industries, and biosciences is now entering a new phase. This mirrors a rise in systems biology that re‐asserts the dominance of key nodes in global bioeconomy hierarchies.

Suggested Citation

  • Philip Cooke, 2009. "The Economic Geography Of Knowledge Flow Hierarchies Among Internationally Networked Medical Bioclusters: A Scientometric Analysis," Tijdschrift voor Economische en Sociale Geografie, Royal Dutch Geographical Society KNAG, vol. 100(3), pages 332-347, July.
  • Handle: RePEc:bla:tvecsg:v:100:y:2009:i:3:p:332-347
    DOI: 10.1111/j.1467-9663.2009.00506.x
    as

    Download full text from publisher

    File URL: https://doi.org/10.1111/j.1467-9663.2009.00506.x
    Download Restriction: no

    File URL: https://libkey.io/10.1111/j.1467-9663.2009.00506.x?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Philip Cooke, 2002. "Biotechnology Clusters as Regional, Sectoral Innovation Systems," International Regional Science Review, , vol. 25(1), pages 8-37, January.
    2. Feldman, Maryann P. & Audretsch, David B., 1999. "Innovation in cities:: Science-based diversity, specialization and localized competition," European Economic Review, Elsevier, vol. 43(2), pages 409-429, February.
    3. Cooke, Phil, 2005. "Regionally asymmetric knowledge capabilities and open innovation: Exploring 'Globalisation 2'--A new model of industry organisation," Research Policy, Elsevier, vol. 34(8), pages 1128-1149, October.
    4. Philip Cooke, 2005. "Rational drug design, the knowledge value chain and bioscience megacentres," Cambridge Journal of Economics, Cambridge Political Economy Society, vol. 29(3), pages 325-341, May.
    5. Glaeser, Edward L & Hedi D. Kallal & Jose A. Scheinkman & Andrei Shleifer, 1992. "Growth in Cities," Journal of Political Economy, University of Chicago Press, vol. 100(6), pages 1126-1152, December.
      • Edward L. Glaeser & Hedi D. Kallal & Jose A. Scheinkman & Andrei Shleifer, 1991. "Growth in Cities," NBER Working Papers 3787, National Bureau of Economic Research, Inc.
      • Glaeser, Edward Ludwig & Kallal, Hedi D. & Scheinkman, Jose A. & Shleifer, Andrei, 1992. "Growth in Cities," Scholarly Articles 3451309, Harvard University Department of Economics.
    6. Ron Boschma, 2005. "Proximity and Innovation: A Critical Assessment," Regional Studies, Taylor & Francis Journals, vol. 39(1), pages 61-74.
    7. Steven Klepper, 2002. "The capabilities of new firms and the evolution of the US automobile industry," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 11(4), pages 645-666, August.
    8. Jason Owen-Smith & Walter W. Powell, 2004. "Knowledge Networks as Channels and Conduits: The Effects of Spillovers in the Boston Biotechnology Community," Organization Science, INFORMS, vol. 15(1), pages 5-21, February.
    9. Philip Cooke, 2004. "The Molecular Biology Revolution and the Rise of Bioscience Megacentres in North America and Europe," Environment and Planning C, , vol. 22(2), pages 161-177, April.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. ., 2011. "Introduction to the Handbook of Regional Innovation and Growth," Chapters, in: Philip Cooke & Bjørn Asheim & Ron Boschma & Ron Martin & Dafna Schwartz & Franz Tödtling (ed.), Handbook of Regional Innovation and Growth, chapter 1, Edward Elgar Publishing.
    2. Stefan Hennemann & Diego Rybski & Ingo Liefner, 2011. "The Myth of Global Science," ERSA conference papers ersa10p246, European Regional Science Association.
    3. Markus M. Bugge & Teis Hansen & Antje Klitkou, 2016. "What Is the Bioeconomy? A Review of the Literature," Sustainability, MDPI, vol. 8(7), pages 1-22, July.
    4. Sylvie Benoit, 2022. "Industrial anchorage in bioeconomy: what role does logistics governance play? [Ancrage industriel en bioéconomie : quel rôle joue la gouvernance logistique ?]," Post-Print hal-03984202, HAL.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Benner, Maximilian, 2009. "What do we know about clusters? In search of effective cluster policies," MPRA Paper 43848, University Library of Munich, Germany, revised 2009.
    2. Abbasiharofteh, Milad & Kogler, Dieter F. & Lengyel, Balázs, 2023. "Atypical combinations of technologies in regional co-inventor networks," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, vol. 52(10), pages 1-1.
    3. Carbonara , Nunzia & Tavassoli, Sam, 2013. "The Role of Knowledge Heterogeneity on the Innovative Capability of Industrial Districts," Papers in Innovation Studies 2013/35, Lund University, CIRCLE - Centre for Innovation Research.
    4. Nunzia Carbonara, 2012. "Industrial district hetereogeneity and performance: evidence from Italy," Chapters, in: Charlie Karlsson & Börje Johansson & Roger R. Stough (ed.), Entrepreneurship, Social Capital and Governance, chapter 4, pages 83-101, Edward Elgar Publishing.
    5. Rosina Moreno & Ernest Miguélez, 2012. "A Relational Approach To The Geography Of Innovation: A Typology Of Regions," Journal of Economic Surveys, Wiley Blackwell, vol. 26(3), pages 492-516, July.
    6. Ron Boschma & Ron Martin, 2010. "The Aims and Scope of Evolutionary Economic Geography," Chapters, in: Ron Boschma & Ron Martin (ed.), The Handbook of Evolutionary Economic Geography, chapter 1, Edward Elgar Publishing.
    7. Roberto Ercole & Robert O'neill, 2017. "The Influence of Agglomeration Externalities on Manufacturing Growth Within Indonesian Locations," Growth and Change, Wiley Blackwell, vol. 48(1), pages 91-126, March.
    8. Ron Boschma & Simona Iammarino, 2009. "Related Variety, Trade Linkages, and Regional Growth in Italy," Economic Geography, Clark University, vol. 85(3), pages 289-311, July.
    9. Aurélie LALANNE & Guillaume POUYANNE, 2012. "Ten years of metropolization in economics: a bibliometric approach (In French)," Cahiers du GREThA (2007-2019) 2012-11, Groupe de Recherche en Economie Théorique et Appliquée (GREThA).
    10. Tubiana, Matteo & Miguelez, Ernest & Moreno, Rosina, 2022. "In knowledge we trust: Learning-by-interacting and the productivity of inventors," Research Policy, Elsevier, vol. 51(1).
    11. Christophe Carrincazeaux & Frédéric Gaschet, 2006. "Knowledge and the diversity of innovation systems: a comparative analysis of European regions," Post-Print hal-00257384, HAL.
    12. Delgado, Mercedes & Porter, Michael E. & Stern, Scott, 2014. "Clusters, convergence, and economic performance," Research Policy, Elsevier, vol. 43(10), pages 1785-1799.
    13. Feldman, Maryann P. & Kogler, Dieter F., 2010. "Stylized Facts in the Geography of Innovation," Handbook of the Economics of Innovation, in: Bronwyn H. Hall & Nathan Rosenberg (ed.), Handbook of the Economics of Innovation, edition 1, volume 1, chapter 0, pages 381-410, Elsevier.
    14. Haifeng Qian, 2018. "Knowledge-Based Regional Economic Development: A Synthetic Review of Knowledge Spillovers, Entrepreneurship, and Entrepreneurial Ecosystems," Economic Development Quarterly, , vol. 32(2), pages 163-176, May.
    15. Albin Skog & Örjan Sölvell, 2020. "The dark side of agglomeration, sustained wealth and transposition of trading institutions—the case of Bordeaux in the 18th and 19th centuries," Journal of Economic Geography, Oxford University Press, vol. 20(1), pages 67-91.
    16. Roberto Ganau & Eleonora Di Maria, 2014. "Determinants of technological innovation in SMEs. Firm-level factors, agglomeration economies and the role of KIBS providers," ERSA conference papers ersa14p820, European Regional Science Association.
    17. Breandán Ó hUallacháin, 2011. "Does inventive intensity affect urban prosperity?," Regional Science Policy & Practice, Wiley Blackwell, vol. 3(4), pages 401-420, November.
    18. Rammer, Christian & Kinne, Jan & Blind, Knut, 2016. "Microgeography of innovation in the city: Location patterns of innovative firms in Berlin," ZEW Discussion Papers 16-080, ZEW - Leibniz Centre for European Economic Research.
    19. Iritié, B. G. Jean-Jacques, 2014. "Enjeux des politiques industrielles basées sur les clusters d'innovation: cas des pôles de compétitivité [Issues of Innovative Clusters-based Industrial Policy: Case of Pole of Competitiveness]," MPRA Paper 54429, University Library of Munich, Germany.
    20. Rakas, Marija & Hain, Daniel S., 2019. "The state of innovation system research: What happens beneath the surface?," Research Policy, Elsevier, vol. 48(9), pages 1-1.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bla:tvecsg:v:100:y:2009:i:3:p:332-347. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Wiley Content Delivery (email available below). General contact details of provider: http://www.blackwellpublishing.com/journal.asp?ref=0040-747X .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.