IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0227472.html
   My bibliography  Save this article

Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis

Author

Listed:
  • Paulo Ruiz-Grosso
  • Rodrigo Cachay
  • Adriana de la Flor
  • Alvaro Schwalb
  • Cesar Ugarte-Gil

Abstract

Background: Depression is a common comorbidity of tuberculosis (TB) and is associated with poor adherence to treatment of multiple disorders. We conducted a systematic review to synthesize the existing evidence on the relationship between depression and negative outcomes of TB treatment. Methods: We systematically reviewed studies that evaluated depressive symptoms (DS) directly or indirectly through psychological distress (PD) and measured negative treatment outcomes of drug-sensitive pulmonary TB, defined as death, loss to follow-up, or non-adherence. Sources included PubMed, Global Health Library, Embase, Scopus and Web of Science from inception to August 2019. Results: Of the 2,970 studies initially identified, eight articles were eligible for inclusion and two were used for the primary outcome meta-analysis. We found a strong association between DS and negative TB treatment outcomes (OR = 4.26; CI95%:2.33–7.79; I2 = 0%). DS were also associated with loss to follow-up (OR = 8.70; CI95%:6.50–11.64; I2 = 0%) and death (OR = 2.85; CI95%:1.52–5.36; I2 = 0%). Non-adherence was not associated with DS and PD (OR = 1.34; CI95%:0.70–2.72; I2 = 94.36) or PD alone (OR = 0.92; CI95%:0.81–1.05; I2 = 0%). Conclusions: DS are associated with the negative TB treatment outcomes of death and loss to follow-up. Considerable heterogeneity exists in the definition of depression and outcomes such as non-adherence across the limited number of studies on this topic.

Suggested Citation

  • Paulo Ruiz-Grosso & Rodrigo Cachay & Adriana de la Flor & Alvaro Schwalb & Cesar Ugarte-Gil, 2020. "Association between tuberculosis and depression on negative outcomes of tuberculosis treatment: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(1), pages 1-13, January.
    • Handle: RePEc:plo:pone00:0227472
    DOI: 10.1371/journal.pone.0227472
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227472
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227472&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0227472?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Narges Alipanah & Leah Jarlsberg & Cecily Miller & Nguyen Nhat Linh & Dennis Falzon & Ernesto Jaramillo & Payam Nahid, 2018. "Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies," PLOS Medicine, Public Library of Science, vol. 15(7), pages 1-44, July.
    2. Salla A Munro & Simon A Lewin & Helen J Smith & Mark E Engel & Atle Fretheim & Jimmy Volmink, 2007. "Patient Adherence to Tuberculosis Treatment: A Systematic Review of Qualitative Research," PLOS Medicine, Public Library of Science, vol. 4(7), pages 1-16, July.
    3. Salla A Munro, 2007. "Patient Adherence to Tuberculosis Treatment: A Systematic Review of Qualitative Research," Working Papers id:1107, eSocialSciences.
    4. Cesar Ugarte-Gil & Paulo Ruiz & Carlos Zamudio & Luz Canaza & Larissa Otero & Hever Kruger & Carlos Seas, 2013. "Association of Major Depressive Episode with Negative Outcomes of Tuberculosis Treatment," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-7, July.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Halim Ismail & Naiemy Reffin & Sharifa Ezat Wan Puteh & Mohd Rohaizat Hassan, 2021. "Compliance of Healthcare Worker’s toward Tuberculosis Preventive Measures in Workplace: A Systematic Literature Review," IJERPH, MDPI, vol. 18(20), pages 1-21, October.
    2. Chih-An Wang & Chia-Hung Chen & Wen-Che Hsieh & Tzu-Ju Hsu & Chung-Y. Hsu & Yung-Chi Cheng & Chao-Yu Hsu, 2023. "Risk of Herpes Zoster in Patients with Pulmonary Tuberculosis—A Population-Based Cohort Study," IJERPH, MDPI, vol. 20(3), pages 1-9, February.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Shahed Hossain & Mohammad Abdul Quaiyum & Khalequ Zaman & Sayera Banu & Mohammad Ashaque Husain & Mohammad Akramul Islam & Erwin Cooreman & Martien Borgdorff & Knut Lönnroth & Abdul Hamid Salim & Fran, 2012. "Socio Economic Position in TB Prevalence and Access to Services: Results from a Population Prevalence Survey and a Facility-Based Survey in Bangladesh," PLOS ONE, Public Library of Science, vol. 7(9), pages 1-8, September.
    2. Francine Mwayuma Birungi & Stephen Michael Graham & Jeannine Uwimana & Angèle Musabimana & Brian van Wyk, 2019. "Adherence to isoniazid preventive therapy among child contacts in Rwanda: A mixed-methods study," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-16, February.
    3. Imad Cherkaoui & Radia Sabouni & Iraqi Ghali & Darya Kizub & Alexander C Billioux & Kenza Bennani & Jamal Eddine Bourkadi & Abderrahmane Benmamoun & Ouafae Lahlou & Rajae El Aouad & Kelly E Dooley, 2014. "Treatment Default amongst Patients with Tuberculosis in Urban Morocco: Predicting and Explaining Default and Post-Default Sputum Smear and Drug Susceptibility Results," PLOS ONE, Public Library of Science, vol. 9(4), pages 1-9, April.
    4. Pinho, S.T.R. & Rodrigues, P. & Andrade, R.F.S. & Serra, H. & Lopes, J.S. & Gomes, M.G.M., 2015. "Impact of tuberculosis treatment length and adherence under different transmission intensities," Theoretical Population Biology, Elsevier, vol. 104(C), pages 68-77.
    5. Thomas N Nissen & Michala V Rose & Godfather Kimaro & Ib C Bygbjerg & Sayoki G Mfinanga & Pernille Ravn, 2012. "Challenges of Loss to Follow-up in Tuberculosis Research," PLOS ONE, Public Library of Science, vol. 7(7), pages 1-8, July.
    6. de Vries, H. & van de Klundert, J.J. & Wagelmans, A.P.M., 2013. "Health Benets of Roadside Healthcare Services," Econometric Institute Research Papers EI 2014-01, Erasmus University Rotterdam, Erasmus School of Economics (ESE), Econometric Institute.
    7. Benissa E. Salem & Erin Klansek & Donald E. Morisky & Sanghyuk S. Shin & Kartik Yadav & Alicia H. Chang & Adeline M. Nyamathi, 2020. "Acceptability and Feasibility of a Nurse-Led, Community Health Worker Partnered Latent Tuberculosis Medication Adherence Model for Homeless Adults," IJERPH, MDPI, vol. 17(22), pages 1-14, November.
    8. Titilola Makanjuola & Henock B Taddese & Andrew Booth, 2014. "Factors Associated with Adherence to Treatment with Isoniazid for the Prevention of Tuberculosis amongst People Living with HIV/AIDS: A Systematic Review of Qualitative Data," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-13, February.
    9. Rosa van Hoorn & Ernesto Jaramillo & David Collins & Agnes Gebhard & Susan van den Hof, 2016. "The Effects of Psycho-Emotional and Socio-Economic Support for Tuberculosis Patients on Treatment Adherence and Treatment Outcomes – A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-27, April.
    10. Samanta Madeira de Oliveira & Stephan Altmayer & Matheus Zanon & Luzielio Alves Sidney-Filho & Ana Luiza Schneider Moreira & Paulo de Tarso Dalcin & Anderson Garcez & Bruno Hochhegger & José da Silva , 2018. "Predictors of noncompliance to pulmonary tuberculosis treatment: An insight from South America," PLOS ONE, Public Library of Science, vol. 13(9), pages 1-10, September.
    11. Núñez Ares, José & de Vries, Harwin & Huisman, Dennis, 2016. "A column generation approach for locating roadside clinics in Africa based on effectiveness and equity," European Journal of Operational Research, Elsevier, vol. 254(3), pages 1002-1016.
    12. HaiYang Zhang & John Ehiri & Huan Yang & Shenglan Tang & Ying Li, 2016. "Impact of Community-Based DOT on Tuberculosis Treatment Outcomes: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-19, February.
    13. Kim, Min Kyong & Bhattacharya, Jayanta & Bhattacharya, Joydeep, 2024. "Is income inequality linked to infectious disease prevalence? A hypothesis-generating study using tuberculosis," Social Science & Medicine, Elsevier, vol. 345(C).
    14. Natasha Chida & Zara Ansari & Hamidah Hussain & Maria Jaswal & Stephen Symes & Aamir J Khan & Shama Mohammed, 2015. "Determinants of Default from Tuberculosis Treatment among Patients with Drug-Susceptible Tuberculosis in Karachi, Pakistan: A Mixed Methods Study," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-14, November.
    15. Hugh Waddington & Birte Snilstveit & Jorge Garcia Hombrados & Martina Vojtkova & Jock Anderson & Howard White, 2012. "PROTOCOL: Farmer Field Schools for Improving Farming Practices and Farmer Outcomes in Low‐ and Middle‐income Countries: A Systematic Review," Campbell Systematic Reviews, John Wiley & Sons, vol. 8(1), pages 1-48.
    16. Hadley, Mary, 2011. "Does increase in utilisation rates alone indicate the success of a user fee removal policy? A qualitative case study from Zambia," Health Policy, Elsevier, vol. 103(2), pages 244-254.
    17. Lewin, Simon & Green, Judith, 2009. "Ritual and the organisation of care in primary care clinics in Cape Town, South Africa," Social Science & Medicine, Elsevier, vol. 68(8), pages 1464-1471, April.
    18. Wei, Xiaolin & Walley, John & Zhao, Jin & Yao, Hongyan & Liu, Jianjun & Newell, James, 2009. "Why financial incentives did not reach the poor tuberculosis patients? A qualitative study of a Fidelis funded project in Shanxi, China," Health Policy, Elsevier, vol. 90(2-3), pages 206-213, May.
    19. Minlan Xu & Urban Markström & Juncheng Lyu & Lingzhong Xu, 2017. "Detection of Low Adherence in Rural Tuberculosis Patients in China: Application of Morisky Medication Adherence Scale," IJERPH, MDPI, vol. 14(3), pages 1-10, March.
    20. Victoria A Wade & Jonathan Karnon & Jaklin A Eliott & Janet E Hiller, 2012. "Home Videophones Improve Direct Observation in Tuberculosis Treatment: A Mixed Methods Evaluation," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-13, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0227472. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.