The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study
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DOI: 10.1371/journal.pgen.1002003
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- Vivian G. Cheung & Richard S. Spielman & Kathryn G. Ewens & Teresa M. Weber & Michael Morley & Joshua T. Burdick, 2005. "Mapping determinants of human gene expression by regional and genome-wide association," Nature, Nature, vol. 437(7063), pages 1365-1369, October.
- Joseph K. Pickrell & John C. Marioni & Athma A. Pai & Jacob F. Degner & Barbara E. Engelhardt & Everlyne Nkadori & Jean-Baptiste Veyrieras & Matthew Stephens & Yoav Gilad & Jonathan K. Pritchard, 2010. "Understanding mechanisms underlying human gene expression variation with RNA sequencing," Nature, Nature, vol. 464(7289), pages 768-772, April.
- Stephen B. Montgomery & Micha Sammeth & Maria Gutierrez-Arcelus & Radoslaw P. Lach & Catherine Ingle & James Nisbett & Roderic Guigo & Emmanouil T. Dermitzakis, 2010. "Transcriptome genetics using second generation sequencing in a Caucasian population," Nature, Nature, vol. 464(7289), pages 773-777, April.
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- Zari Dastani & Marie-France Hivert & Nicholas Timpson & John R B Perry & Xin Yuan & Robert A Scott & Peter Henneman & Iris M Heid & Jorge R Kizer & Leo-Pekka Lyytikäinen & Christian Fuchsberger & Tosh, 2012. "Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals," PLOS Genetics, Public Library of Science, vol. 8(3), pages 1-23, March.
- Josine L Min & Jennifer M Taylor & J Brent Richards & Tim Watts & Fredrik H Pettersson & John Broxholme & Kourosh R Ahmadi & Gabriela L Surdulescu & Ernesto Lowy & Christian Gieger & Chris Newton-Cheh, 2011. "The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits," PLOS ONE, Public Library of Science, vol. 6(7), pages 1-14, July.
- Lina-Marcela Diaz-Gallo & Elena Sánchez & Norberto Ortego-Centeno & Jose Mario Sabio & Francisco J García-Hernández & Enrique de Ramón & Miguel A González-Gay & Torsten Witte & Hans-Joachim Anders & M, 2013. "Evidence of New Risk Genetic Factor to Systemic Lupus Erythematosus: The UBASH3A Gene," PLOS ONE, Public Library of Science, vol. 8(4), pages 1-5, April.
- Nicoló Fusi & Oliver Stegle & Neil D Lawrence, 2012. "Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies," PLOS Computational Biology, Public Library of Science, vol. 8(1), pages 1-9, January.
- Maggie C Y Ng & Daniel Shriner & Brian H Chen & Jiang Li & Wei-Min Chen & Xiuqing Guo & Jiankang Liu & Suzette J Bielinski & Lisa R Yanek & Michael A Nalls & Mary E Comeau & Laura J Rasmussen-Torvik &, 2014. "Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes," PLOS Genetics, Public Library of Science, vol. 10(8), pages 1-14, August.
- Diptavo Dutta & Yuan He & Ashis Saha & Marios Arvanitis & Alexis Battle & Nilanjan Chatterjee, 2022. "Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
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