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Integrative multi-omics analysis reveals genetic and heterotic contributions to male fertility and yield in potato

Author

Listed:
  • Dawei Li

    (Chinese Academy of Agricultural Sciences)

  • Zedong Geng

    (Huazhong Agricultural University)

  • Shixuan Xia

    (Chinese Academy of Agricultural Sciences
    Huazhong Agricultural University)

  • Hui Feng

    (Huazhong Agricultural University)

  • Xiuhan Jiang

    (Chinese Academy of Agricultural Sciences)

  • Hui Du

    (Chinese Academy of Agricultural Sciences)

  • Pei Wang

    (Chinese Academy of Agricultural Sciences)

  • Qun Lian

    (Chinese Academy of Agricultural Sciences)

  • Yanhui Zhu

    (Chinese Academy of Agricultural Sciences)

  • Yuxin Jia

    (Yunnan Normal University)

  • Yao Zhou

    (Chinese Academy of Agricultural Sciences)

  • Yaoyao Wu

    (Nanjing Agricultural University)

  • Chenglong Huang

    (Huazhong Agricultural University)

  • Guangtao Zhu

    (Yunnan Normal University)

  • Yi Shang

    (Yunnan Normal University)

  • Huihui Li

    (Chinese Academy of Agricultural Sciences
    Chinese Academy of Agricultural Sciences)

  • Thomas Städler

    (ETH Zurich)

  • Wanneng Yang

    (Huazhong Agricultural University)

  • Sanwen Huang

    (Chinese Academy of Agricultural Sciences
    Chinese Academy of Tropical Agricultural Sciences)

  • Chunzhi Zhang

    (Chinese Academy of Agricultural Sciences)

Abstract

The genetic analysis of potato is hampered by the complexity of tetrasomic inheritance. An ongoing effort aims to transform the clonally propagated tetraploid potato into a seed-propagated diploid crop, which would make genetic analyses much easier owing to disomic inheritance. Here, we construct and report the large-scale genetic and heterotic characteristics of a diploid F2 potato population derived from the cross of two highly homozygous inbred lines. We investigate 20,382 traits generated from multi-omics dataset and identify 25,770 quantitative trait loci (QTLs). Coupled with gene expression data, we construct a systems-genetics network for gene discovery in potatoes. Importantly, we explore the genetic basis of heterosis in this population, especially for yield and male fertility heterosis. We find that positive heterotic effects of yield-related QTLs and negative heterotic effects of metabolite QTLs (mQTLs) contribute to yield heterosis. Additionally, we identify a PME gene with a dominance heterotic effect that plays an important role in male fertility heterosis. This study provides genetic resources for the potato community and will facilitate the application of heterosis in diploid potato breeding.

Suggested Citation

  • Dawei Li & Zedong Geng & Shixuan Xia & Hui Feng & Xiuhan Jiang & Hui Du & Pei Wang & Qun Lian & Yanhui Zhu & Yuxin Jia & Yao Zhou & Yaoyao Wu & Chenglong Huang & Guangtao Zhu & Yi Shang & Huihui Li & , 2024. "Integrative multi-omics analysis reveals genetic and heterotic contributions to male fertility and yield in potato," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-53044-4
    DOI: 10.1038/s41467-024-53044-4
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    References listed on IDEAS

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