A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes
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DOI: 10.1038/s41467-024-51134-x
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- Ulrike Steffen & Carolien A. Koeleman & Maria V. Sokolova & Holger Bang & Arnd Kleyer & Jürgen Rech & Harald Unterweger & Martin Schicht & Fabian Garreis & Jonas Hahn & Fabian T. Andes & Fabian Hartma, 2020. "IgA subclasses have different effector functions associated with distinct glycosylation profiles," Nature Communications, Nature, vol. 11(1), pages 1-12, December.
- Woei-Yuh Saw & Erwin Tantoso & Husna Begum & Lihan Zhou & Ruiyang Zou & Cheng He & Sze Ling Chan & Linda Wei-Lin Tan & Lai-Ping Wong & Wenting Xu & Don Kyin Nwe Moong & Yenly Lim & Bowen Li & Nisha Es, 2017. "Establishing multiple omics baselines for three Southeast Asian populations in the Singapore Integrative Omics Study," Nature Communications, Nature, vol. 8(1), pages 1-11, December.
- Tianxiao Huan & Jian Rong & Chunyu Liu & Xiaoling Zhang & Kahraman Tanriverdi & Roby Joehanes & Brian H. Chen & Joanne M. Murabito & Chen Yao & Paul Courchesne & Peter J. Munson & Christopher J. O’Don, 2015. "Genome-wide identification of microRNA expression quantitative trait loci," Nature Communications, Nature, vol. 6(1), pages 1-9, May.
- Marjolein J. Peters & Roby Joehanes & Luke C. Pilling & Claudia Schurmann & Karen N. Conneely & Joseph Powell & Eva Reinmaa & George L. Sutphin & Alexandra Zhernakova & Katharina Schramm & Yana A. Wil, 2015. "The transcriptional landscape of age in human peripheral blood," Nature Communications, Nature, vol. 6(1), pages 1-14, December.
- Karsten Suhre & So-Youn Shin & Ann-Kristin Petersen & Robert P. Mohney & David Meredith & Brigitte Wägele & Elisabeth Altmaier & Panos Deloukas & Jeanette Erdmann & Elin Grundberg & Christopher J. Ham, 2011. "Human metabolic individuality in biomedical and pharmaceutical research," Nature, Nature, vol. 477(7362), pages 54-60, September.
- Karsten Suhre & Matthias Arnold & Aditya Mukund Bhagwat & Richard J. Cotton & Rudolf Engelke & Johannes Raffler & Hina Sarwath & Gaurav Thareja & Annika Wahl & Robert Kirk DeLisle & Larry Gold & Marij, 2017. "Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome," Nature Communications, Nature, vol. 8(1), pages 1-1, April.
- J. Oh & S. J. Matkovich & A. E. Riek & S. M. Bindom & J. S. Shao & R. D. Head & R. A. Barve & M. S. Sands & G. Carmeliet & P. Osei-Owusu & R. H. Knutsen & H. Zhang & K. J. Blumer & C. G. Nichols & R. , 2020. "Macrophage secretion of miR-106b-5p causes renin-dependent hypertension," Nature Communications, Nature, vol. 11(1), pages 1-12, December.
- Shaza B. Zaghlool & Brigitte Kühnel & Mohamed A. Elhadad & Sara Kader & Anna Halama & Gaurav Thareja & Rudolf Engelke & Hina Sarwath & Eman K. Al-Dous & Yasmin A. Mohamoud & Thomas Meitinger & Rory Wi, 2020. "Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits," Nature Communications, Nature, vol. 11(1), pages 1-12, December.
- Song Wu & Wei Zhu & Patricia Thompson & Yusuf A Hannun, 2018. "Evaluating intrinsic and non-intrinsic cancer risk factors," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Chengxin Dai & Anja Füllgrabe & Julianus Pfeuffer & Elizaveta M. Solovyeva & Jingwen Deng & Pablo Moreno & Selvakumar Kamatchinathan & Deepti Jaiswal Kundu & Nancy George & Silvie Fexova & Björn Grüni, 2021. "A proteomics sample metadata representation for multiomics integration and big data analysis," Nature Communications, Nature, vol. 12(1), pages 1-8, December.
- Arthur Gilly & Young-Chan Park & Grace Png & Andrei Barysenka & Iris Fischer & Thea Bjørnland & Lorraine Southam & Daniel Suveges & Sonja Neumeyer & N. William Rayner & Emmanouil Tsafantakis & Maria K, 2020. "Whole-genome sequencing analysis of the cardiometabolic proteome," Nature Communications, Nature, vol. 11(1), pages 1-9, December.
- Johannes Kettunen & Ayşe Demirkan & Peter Würtz & Harmen H.M. Draisma & Toomas Haller & Rajesh Rawal & Anika Vaarhorst & Antti J. Kangas & Leo-Pekka Lyytikäinen & Matti Pirinen & René Pool & Antti-Pek, 2016. "Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA," Nature Communications, Nature, vol. 7(1), pages 1-9, September.
- Karsten Suhre & Matthias Arnold & Aditya Mukund Bhagwat & Richard J. Cotton & Rudolf Engelke & Johannes Raffler & Hina Sarwath & Gaurav Thareja & Annika Wahl & Robert Kirk DeLisle & Larry Gold & Marij, 2017. "Connecting genetic risk to disease end points through the human blood plasma proteome," Nature Communications, Nature, vol. 8(1), pages 1-14, April.
- Shaza B. Zaghlool & Sapna Sharma & Megan Molnar & Pamela R. Matías-García & Mohamed A. Elhadad & Melanie Waldenberger & Annette Peters & Wolfgang Rathmann & Johannes Graumann & Christian Gieger & Hara, 2021. "Revealing the role of the human blood plasma proteome in obesity using genetic drivers," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
- Shaza B. Zaghlool & Anna Halama & Nisha Stephan & Valborg Gudmundsdottir & Vilmundur Gudnason & Lori L. Jennings & Manonanthini Thangam & Emma Ahlqvist & Rayaz A. Malik & Omar M. E. Albagha & Abdul Ba, 2022. "Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- M. Reza Sailani & Ahmed A. Metwally & Wenyu Zhou & Sophia Miryam Schüssler-Fiorenza Rose & Sara Ahadi & Kevin Contrepois & Tejaswini Mishra & Martin Jinye Zhang & Łukasz Kidziński & Theodore J. Chu & , 2020. "Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California," Nature Communications, Nature, vol. 11(1), pages 1-12, December.
- Tianxiao Huan & Roby Joehanes & Ci Song & Fen Peng & Yichen Guo & Michael Mendelson & Chen Yao & Chunyu Liu & Jiantao Ma & Melissa Richard & Golareh Agha & Weihua Guan & Lynn M. Almli & Karen N. Conne, 2019. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
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