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BaTwa populations from Zambia retain ancestry of past hunter-gatherer groups

Author

Listed:
  • Gwenna Breton

    (Uppsala University
    Sahlgrenska University Hospital)

  • Lawrence Barham

    (University of Liverpool)

  • George Mudenda

    (Livingstone Museum
    National Museums Board)

  • Himla Soodyall

    (University of the Witwatersrand and National Health Laboratory Service
    Academy of Science of South Africa)

  • Carina M. Schlebusch

    (Uppsala University
    University of Johannesburg
    SciLifeLab)

  • Mattias Jakobsson

    (Uppsala University
    University of Johannesburg
    SciLifeLab)

Abstract

Sub-equatorial Africa is today inhabited predominantly by Bantu-speaking groups of Western African descent who brought agriculture to the Luangwa valley in eastern Zambia ~2000 years ago. Before their arrival the area was inhabited by hunter-gatherers, who in many cases were subsequently replaced, displaced or assimilated. In Zambia, we know little about the genetic affinities of these hunter-gatherers. We examine ancestry of two isolated communities in Zambia, known as BaTwa and possible descendants of recent hunter-gatherers. We genotype over two million genome-wide SNPs from two BaTwa populations (total of 80 individuals) and from three comparative farming populations to: (i) determine if the BaTwa carry genetic links to past hunter-gatherer-groups, and (ii) characterise the genetic affinities of past Zambian hunter-gatherer-groups. The BaTwa populations do harbour a hunter-gatherer-like genetic ancestry and Western African ancestry. The hunter-gatherer component is a unique local signature, intermediate between current-day Khoe-San ancestry from southern Africa and central African rainforest hunter-gatherer ancestry.

Suggested Citation

  • Gwenna Breton & Lawrence Barham & George Mudenda & Himla Soodyall & Carina M. Schlebusch & Mattias Jakobsson, 2024. "BaTwa populations from Zambia retain ancestry of past hunter-gatherer groups," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-50733-y
    DOI: 10.1038/s41467-024-50733-y
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    References listed on IDEAS

    as
    1. Nick Patterson & Alkes L Price & David Reich, 2006. "Population Structure and Eigenanalysis," PLOS Genetics, Public Library of Science, vol. 2(12), pages 1-20, December.
    2. Rasmus Nielsen & Joshua M. Akey & Mattias Jakobsson & Jonathan K. Pritchard & Sarah Tishkoff & Eske Willerslev, 2017. "Tracing the peopling of the world through genomics," Nature, Nature, vol. 541(7637), pages 302-310, January.
    3. Mark Lipson & Elizabeth A. Sawchuk & Jessica C. Thompson & Jonas Oppenheimer & Christian A. Tryon & Kathryn L. Ranhorn & Kathryn M. Luna & Kendra A. Sirak & Iñigo Olalde & Stanley H. Ambrose & John W., 2022. "Ancient DNA and deep population structure in sub-Saharan African foragers," Nature, Nature, vol. 603(7900), pages 290-296, March.
    4. Maanasa Raghavan & Pontus Skoglund & Kelly E. Graf & Mait Metspalu & Anders Albrechtsen & Ida Moltke & Simon Rasmussen & Thomas W. Stafford Jr & Ludovic Orlando & Ene Metspalu & Monika Karmin & Kristi, 2014. "Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans," Nature, Nature, vol. 505(7481), pages 87-91, January.
    5. Cesar A. Fortes-Lima & Concetta Burgarella & Rickard Hammarén & Anders Eriksson & Mário Vicente & Cecile Jolly & Armando Semo & Hilde Gunnink & Sara Pacchiarotti & Leon Mundeke & Igor Matonda & Joseph, 2024. "The genetic legacy of the expansion of Bantu-speaking peoples in Africa," Nature, Nature, vol. 625(7995), pages 540-547, January.
    6. Mark Lipson & Isabelle Ribot & Swapan Mallick & Nadin Rohland & Iñigo Olalde & Nicole Adamski & Nasreen Broomandkhoshbacht & Ann Marie Lawson & Saioa López & Jonas Oppenheimer & Kristin Stewardson & R, 2020. "Ancient West African foragers in the context of African population history," Nature, Nature, vol. 577(7792), pages 665-670, January.
    7. Etienne Patin & Katherine J. Siddle & Guillaume Laval & Hélène Quach & Christine Harmant & Noémie Becker & Alain Froment & Béatrice Régnault & Laure Lemée & Simon Gravel & Jean-Marie Hombert & Lolke V, 2014. "The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists," Nature Communications, Nature, vol. 5(1), pages 1-10, May.
    8. Deepti Gurdasani & Tommy Carstensen & Fasil Tekola-Ayele & Luca Pagani & Ioanna Tachmazidou & Konstantinos Hatzikotoulas & Savita Karthikeyan & Louise Iles & Martin O. Pollard & Ananyo Choudhury & Gra, 2015. "The African Genome Variation Project shapes medical genetics in Africa," Nature, Nature, vol. 517(7534), pages 327-332, January.
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