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Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa

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  • Xiaoyun Xin

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Peirong Li

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Xiuyun Zhao

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Yangjun Yu

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Weihong Wang

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Guihua Jin

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science)

  • Jiao Wang

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science)

  • Liling Sun

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science)

  • Deshuang Zhang

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Fenglan Zhang

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Shuancang Yu

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

  • Tongbing Su

    (Beijing Academy of Agriculture and Forestry Science
    Beijing Academy of Agriculture and Forestry Science
    Beijing Key Laboratory of Vegetable Germplasms Improvement
    Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China))

Abstract

Global warming has a severe impact on the flowering time and yield of crops. Histone modifications have been well-documented for their roles in enabling plant plasticity in ambient temperature. However, the factor modulating histone modifications and their involvement in habitat adaptation have remained elusive. In this study, through genome-wide pattern analysis and quantitative-trait-locus (QTL) mapping, we reveal that BrJMJ18 is a candidate gene for a QTL regulating thermotolerance in thermotolerant B. rapa subsp. chinensis var. parachinensis (or Caixin, abbreviated to Par). BrJMJ18 encodes an H3K36me2/3 Jumonji demethylase that remodels H3K36 methylation across the genome. We demonstrate that the BrJMJ18 allele from Par (BrJMJ18Par) influences flowering time and plant growth in a temperature-dependent manner via characterizing overexpression and CRISPR/Cas9 mutant plants. We further show that overexpression of BrJMJ18Par can modulate the expression of BrFLC3, one of the five BrFLC orthologs. Furthermore, ChIP-seq and transcriptome data reveal that BrJMJ18Par can regulate chlorophyll biosynthesis under high temperatures. We also demonstrate that three amino acid mutations may account for function differences in BrJMJ18 between subspecies. Based on these findings, we propose a working model in which an H3K36me2/3 demethylase, while not affecting agronomic traits under normal conditions, can enhance resilience under heat stress in Brassica rapa.

Suggested Citation

  • Xiaoyun Xin & Peirong Li & Xiuyun Zhao & Yangjun Yu & Weihong Wang & Guihua Jin & Jiao Wang & Liling Sun & Deshuang Zhang & Fenglan Zhang & Shuancang Yu & Tongbing Su, 2024. "Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-49721-z
    DOI: 10.1038/s41467-024-49721-z
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