Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy
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DOI: 10.1038/s41467-024-48214-3
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- Sheila K. Singh & Cynthia Hawkins & Ian D. Clarke & Jeremy A. Squire & Jane Bayani & Takuichiro Hide & R. Mark Henkelman & Michael D. Cusimano & Peter B. Dirks, 2004. "Identification of human brain tumour initiating cells," Nature, Nature, vol. 432(7015), pages 396-401, November.
- Nicholas J. Fuda & M. Behfar Ardehali & John T. Lis, 2009. "Defining mechanisms that regulate RNA polymerase II transcription in vivo," Nature, Nature, vol. 461(7261), pages 186-192, September.
- Anastasios Liakos & Dimitris Konstantopoulos & Matthieu D. Lavigne & Maria Fousteri, 2020. "Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions," Nature Communications, Nature, vol. 11(1), pages 1-16, December.
- Zhiyuan Yang & Qingwei Zhu & Kunxin Luo & Qiang Zhou, 2001. "The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription," Nature, Nature, vol. 414(6861), pages 317-322, November.
- Joshua M. Dempster & Clare Pacini & Sasha Pantel & Fiona M. Behan & Thomas Green & John Krill-Burger & Charlotte M. Beaver & Scott T. Younger & Victor Zhivich & Hanna Najgebauer & Felicity Allen & Ema, 2019. "Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Jeremy Schwartzentruber & Andrey Korshunov & Xiao-Yang Liu & David T. W. Jones & Elke Pfaff & Karine Jacob & Dominik Sturm & Adam M. Fontebasso & Dong-Anh Khuong Quang & Martje Tönjes & Volker Hovesta, 2012. "Correction: Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma," Nature, Nature, vol. 484(7392), pages 130-130, April.
- Jian Chen & Yanjiao Li & Tzong-Shiue Yu & Renée M. McKay & Dennis K. Burns & Steven G. Kernie & Luis F. Parada, 2012. "A restricted cell population propagates glioblastoma growth after chemotherapy," Nature, Nature, vol. 488(7412), pages 522-526, August.
- Jeremy Schwartzentruber & Andrey Korshunov & Xiao-Yang Liu & David T. W. Jones & Elke Pfaff & Karine Jacob & Dominik Sturm & Adam M. Fontebasso & Dong-Anh Khuong Quang & Martje Tönjes & Volker Hovesta, 2012. "Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma," Nature, Nature, vol. 482(7384), pages 226-231, February.
- Tyler E. Miller & Brian B. Liau & Lisa C. Wallace & Andrew R. Morton & Qi Xie & Deobrat Dixit & Daniel C. Factor & Leo J. Y. Kim & James J. Morrow & Qiulian Wu & Stephen C. Mack & Christopher G. Huber, 2017. "Transcription elongation factors represent in vivo cancer dependencies in glioblastoma," Nature, Nature, vol. 547(7663), pages 355-359, July.
- Shideng Bao & Qiulian Wu & Roger E. McLendon & Yueling Hao & Qing Shi & Anita B. Hjelmeland & Mark W. Dewhirst & Darell D. Bigner & Jeremy N. Rich, 2006. "Glioma stem cells promote radioresistance by preferential activation of the DNA damage response," Nature, Nature, vol. 444(7120), pages 756-760, December.
- Lei Guo & Jia Li & Hongxiang Zeng & Anna G. Guzman & Tingting Li & Minjung Lee & Yubin Zhou & Margaret A. Goodell & Clifford Stephan & Peter J. A. Davies & Mark A Dawson & Deqiang Sun & Yun Huang, 2020. "A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells," Nature Communications, Nature, vol. 11(1), pages 1-16, December.
- Stephen P. Jackson & Jiri Bartek, 2009. "The DNA-damage response in human biology and disease," Nature, Nature, vol. 461(7267), pages 1071-1078, October.
- Christopher J. Lord & Alan Ashworth, 2012. "The DNA damage response and cancer therapy," Nature, Nature, vol. 481(7381), pages 287-294, January.
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